Protein Alignment GramD1B and gramd1a

DIOPT Version :9

• Sequence 1: NP_995623.2
• Gene: GramD1B / 33552
• FlyBaseID: FBgn0085423
• Length: 1249
• Species: Drosophila melanogaster
• Sequence 2: XP_031761291.1
• Gene: gramd1a / 100492510
• XenbaseID: XB-GENE-994631
• Length: 846
• Species: Xenopus tropicalis
• Alignment Length: 1197
• Identity: 284/1197 - (23%)
• Similarity: 457/1197 - (38%)
• Gaps: 408/1197 - (34%)

  Fly    66 TQPDQLQSQTQTQAQL----QPQSQSPSQCQQAQENP-EHLQQQSQPEEELQAEAPGSNAGDRRD 125
            |:|:......:|..||    .|:|.|.|....|:... :..:.|..||...:::|.||....|
 Frog     4 TRPNSFAVAMETLKQLPSLKPPESWSCSSTPSARRRRLKSKKGQRTPESGGRSDAEGSAVRGR-- 66

  Fly   126 SITE---EITITSTTN--SSQSTKLLTIQEAAGSFEQ--SSVSAVSTSSKQIASTTAGGSPPAAA 183
            |:..   |:|.:|...  |:.||...:.|...|.|.:  ....|.|.:......:|...||....
 Frog    67 SLKPPAIEVTPSSEDEAWSNCSTPSASPQRRRGLFRKWLKRREAKSCTGSITPRSTPSNSPAVRR 131

  Fly   184 APGANEFNGSVLRLTQAATSTSPGSISSAGNTATLGAAPSINIVSSESTRDQTQQPQSVDPNGVA 248
            ...::|.:..|.|.::.:...||.::     |.||                         |...|
 Frog   132 RLVSSEVDNMVERGSEGSAEQSPNTL-----TPTL-------------------------PQSAA 166

  Fly   249 APGDSPSSRKSSTSSKGKASQAKLSTSSSGRDEQDISQHRLSDLTQHELSLLRVDREQQVTSSSS 313
            .||           ::|.|.|...|.|..|           :.||            .|::....
 Frog   167 VPG-----------TQGNAQQPTQSNSQPG-----------TPLT------------AQLSGRGF 197

  Fly   314 TSNEKPAKTSRLSERAKKKSWYNVIYPNYKSRAEDFKKLFKDVPNDERLIVDYSCALQRDILVQG 378
            ..|.|           |.:|||:::.|.||.|.|||:|:||.:|:.||||||||||||:|||:||
 Frog   198 IRNSK-----------KMQSWYSMLSPTYKQRNEDFRKIFKKLPDSERLIVDYSCALQKDILLQG 251

  Fly   379 RLYVSQNYVCFHANIFSWETHVSIKWKDVTAITKEKTALVIPNAISISSGKDKYFFATFTSRDKS 443
            |||:|:|::||::|||.|||.:.|:.||:..|.|||||.:|||||.:.:..:|:||.:|.:||:|
 Frog   252 RLYLSENWICFYSNIFRWETTIMIQLKDIQCIKKEKTAKLIPNAIQVCTETEKHFFTSFGARDRS 316

  Fly   444 FLMLFRVWQNTLMNKQFSPQEIWQHVHTCYGDELGLTTDDEDYIDP--TLNKT-NEPDFDFQTAI 505
            ||::||:|||.|::|..||:|:|..||.|||.|||||::||||:.|  .||.. ...||...|.:
 Frog   317 FLLIFRLWQNALLDKTLSPRELWHIVHQCYGTELGLTSEDEDYVSPRDLLNGLGGSEDFPESTDL 381

  Fly   506 DDDSYSQRQSQQSNQSNQSNPLLPQSGNSSASSGGGVRASA-PRKSKTKYFFNSSKSSANASASG 569
            .|                            .||.|..:.|| |:...|..|  :|.:||:
 Frog   382 SD----------------------------TSSRGDTKLSASPQLPATDSF--TSLASAD----- 411

  Fly   570 SDNNKTRESSRKLNKKMKQNAKELTLSSVKPTELSVSVTMSAPNVSSSSTAGSTTASSSTIANHT 634
                                      |.:.|.|
 Frog   412 --------------------------SMIPPAE-------------------------------- 418

  Fly   635 GSGSGSGSLSGSNTAAASGSGSDKM---SAEKKVSTASNSAAVAAAEAAQSLASASSGSGSLESK 696
                        :.||.|.:.||..   |:.:.|:..|..|..|..::..:|....|
 Frog   419 ------------DAAAQSDAQSDSQLEGSSSQTVTPLSEMAGSALLDSLPALDLLPS-------- 463

  Fly   697 MEMKRKLGKMHRQREEGKNAAESVPTDVSDSS------DSEENNLP-FVPTTECTSTHEGRQIVH 754
                                 |.:|||.|::|      |.|.:..| ..|:::.|    ||..::
 Frog   464 ---------------------EELPTDPSNNSTPSSTQDEEASTAPKDTPSSDLT----GRLHIN 503

  Fly   755 TILPINVDTLFNLLFSKSKFITDFHAMRKSTDLVLGEWTKNEEGLQVRTVNVTVQLAASVGPKTS 819
            .:..|:.:.|.:.|.:.::|:.||...||.||:.:..|.::..|.|.|.:|.|:.:...:|||::
 Frog   504 AVYHISAEHLQHALTTDTQFMNDFMEQRKFTDITVNPWMRDGNGKQSRILNYTIPINNPLGPKSA 568

  Fly   820 KVTEYQTQRECSKPGELYSIDVNSVNAGIPYAESFSVLIHFCLARTVDDHTMLSIHTQIKYKKSI 884
            ...|  ||...|..|.:..:|...:..||||.:.|.....:|::....:...|.:.::|.|:|..
 Frog   569 PAIE--TQILHSVKGSVCVLDTQVITQGIPYQDYFYTSHRYCISSVGKNKARLRVSSEICYRKQP 631

  Fly   885 WGVVKGFIEKNTWAGLEDFFG--AQLHALQSETCIPPAKGKG----RRPRRGMNQQSATSTSTTS 943
            |.:|:..||||:|.|:|:.|.  |...|...::|.....|:.    ||.:|.::.:|
 Frog   632 WSLVRAIIEKNSWNGMEEHFSLLADAVAKLDQSCAEEMGGREKPALRRRKRTLSWKS-------- 688

  Fly   944 ITTGALHTATSTDNDSIQESRHPHQQDQHQHQHLHMHHHHHHHHGSQHHHHDARHSHHHHHQPLL 1008
                                                            ||:|..::
 Frog   689 ------------------------------------------------HHNDTNNT--------- 696

  Fly  1009 PHHQQQHPHHWHHRKALLQSGRGTATQIRPLEEAVGPAPAVDPLETQMLAAGGIPGAAVGAAAGH 1073
                                                   |...:|::.::...
 Frog   697 ---------------------------------------ASPQIESERVSRNS------------ 710

  Fly  1074 PLLLEGGKQQQLHHQQQMHHHHLQPHKQHLQQQQLHLGGGDGQPLASGQGSQGHRLRHKGLWLLV 1138
              .:.|....||............|:                                 .|:::.
 Frog   711 --RVSGSISSQLSQLSNRDTSSNIPN---------------------------------ALFVIS 740

  Fly  1139 ILLLCLMLALNVILLLKLWRLEERIDVDLNRRARMPSLAALSE--LPSTNQEWLELLRDQEMAHE 1201
            |:||.|:: ||::|..:||.||...     |..:.....|:|:  .|.::.:|.|:|..|:..|.
 Frog   741 IVLLVLVV-LNMMLFYRLWSLEHTA-----RTFQTWQNYAVSQGRFPQSSADWAEILELQKRFHN 799

  Fly  1202 NELHKWQQVLQTAIELLKKVSIVCEKI 1228
            .|:.||:|.|:.:::||.::.:..:::
 Frog   800 AEVQKWKQTLRASVQLLDEMRMSLQRL 826

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GramD1B	NP_995623.2	PH-GRAM_GRAMDC	358..451	CDD:275406	55/92 (60%)
		DUF4782	751..897	CDD:292635	41/145 (28%)
gramd1a	XP_031761291.1	PH-GRAM_GRAMDC	231..324	CDD:275406	55/92 (60%)
		fibronec_FbpA	<374..>495	CDD:411474	40/254 (16%)
		DUF4782	502..646	CDD:406424	42/145 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	153	1.000	Domainoid score	I4242
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	388	1.000	Inparanoid score	I1967
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D322809at33208
OrthoFinder	1	1.000	-	-		FOG0000885
OrthoInspector	1	1.000	-	-		otm49154
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X567
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.060