DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment kl-2 and Dnah17

DIOPT Version :9

Sequence 1:	NP_001015505.5	Gene:	kl-2 / 3355181	FlyBaseID:	FBgn0001313	Length:	4459	Species:	Drosophila melanogaster
Sequence 2:	XP_006534213.1	Gene:	Dnah17 / 69926	MGIID:	1917176	Length:	4459	Species:	Mus musculus

Alignment Length:	4653	Identity:	1432/4653 - (30%)
Similarity:	2360/4653 - (50%)	Gaps:	413/4653 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 ETDRGSEIAGLVEYVKKITFLYSLDHRDWNAKVINVISIWLINSTELVLTIFYDCDVLTGCLGFP 69
            :.|:..::.|..|.:..:|..:.        |:.|.:.:..:|:..:::.          |||||
Mouse    20 KADKWGKLIGAEENMALLTEFFD--------KIDNPVLVLTLNAAGMIIP----------CLGFP 66

  Fly    70 VAPVIDLCYFIRSSKEIISIHSFHDMVNFGTVQ-DDVDGCLLKILELIYAPI--FRNFMEWGDNV 131
            .:......|||:...|.|:..::...:.:|.:. ..||..:..:.|::|:.:  ..|...|...|
Mouse    67 ESLKSKGVYFIKMKPENITKDNYKTHLIYGDISPTTVDQLIAVVEEVLYSLLNQSENMDGWPRVV 131

  Fly   132 KQRFCTSLDKFLGILTAIYFKMSGMTVLYVPY-------VVKEIAKEISSYDREFVKNLECIAVS 189
            .:.....:.:....:..:..|:.|.|:|.:|.       .:..:.:..||.|...:.::|.|.:.
Mouse   132 SEDIVKQVHRLKNEMFVMGGKIKGKTLLPIPEHLGSLDGTLDSMERIPSSMDNSLLHSIETIIID 196

  Fly   190 WATLIRILLNDKTLTS------PNEYISVGDEFEFWLYRFEVLQGLNAQLDQVDVQQIIRVLRST 248
            |:..||.:|:..:..:      |...:    |||||..|...||.::.||::..|.:|:.:|...
Mouse   197 WSHQIRDVLSKDSAQALLDGLHPLPRV----EFEFWDARLMNLQCIHEQLNRPKVNKIVEILEKA 257

  Fly   249 HSVYIKQIDELIFESTHELMEA---MENIKFLHLLMQPCSQLDFSESPTFVSQLIPRTIHLIRFI 310
            .|.|...:..:....|..|.||   :..:|.|.:|::...|.||:..|:|    |.:.:..|.||
Mouse   258 KSCYWPALQNVYMNVTQGLKEANGIVLYLKPLRILLEEMEQADFTMLPSF----IVKVLSTICFI 318

  Fly   311 WLNSEQYNRRDLITGIFRNLSNQIIRFCTEKVNVEKILSG-SSRFGIKICNMCIDCCLTYKGI-- 372
            |..||.||....:..|.|...||||......::.:::|.| .......:.|:.:...: .||:
Mouse   319 WATSEHYNTPSRVIVILREFCNQIIEMTRTYLSPDEVLKGLQGEIEEVLGNISLSVSV-LKGLFQ 382

  Fly   373 -YDIM---SKTHAKINIRIGWSLDNAMIFNHVDAFMERLNDVIDICESMMVFGRLDESESIPKPQ 433
             ||..   .|...|....:.|...:::.|:.:::|..|:..:.|:.::.:.|.:|:      |.:
Mouse   383 AYDFCCANMKLFFKDRPPVPWEFPSSLAFSRMNSFFHRVQTIEDLYKTAIEFLKLE------KIE 441

  Fly   434 FGGTSGTEFEATADNVENEF--LVTLTALCTDSKEIILNVHKNEWYEEVIKYRRTVQSMEETVQR 496
            .||..|.........:.:|.  ||.:.|.|   |...|:...:.:.::...:...:|.::..:..
Mouse   442 LGGVWGNILGNLVTQIYDEVFELVKVFAEC---KYDPLDPGDSSFDDDYSDFETKIQDLDRRLAT 503

  Fly   497 LMSNVFQHICNVEEALESLNVMIFYSYRSTIRKTFLRQV----SSAWVFFSNEIDSSVHMLMDRS 557
            :....|.. ||   .:||...:::.......|...|.:|    |.....|:.|:|::  .||..:
Mouse   504 IFCQAFDD-CN---CMESSAKLLYMCGGLLERPLILVEVVPRYSVMLEMFNTELDNA--KLMYDA 562

  Fly   558 KM-----------HESWVPYYASRALGYRVHLDRLVW---LCNRLN-SSDWLPNVS-------EA 600
            :|           |::..|...           :|.|   |..||. |..:|.::.       ||
Mouse   563 QMAASADGQIPPIHKNMSPVSG-----------QLKWSLELQERLEVSMKYLKHIEHPVMSSMEA 616

  Fly   601 SVVLKKFESVRREFDKEVKKSFDEWQKNC---CSLLLNQKLDRYLLIRSKKKKGLIECNIDRTIL 662
            .::..|::.:.........|.:.:|.:..   |...|.|.     ||:......||:.|..:.::
Mouse   617 KLIYDKYDEMMGLLQSCRMKKYQQWVEGVDQDCHFNLGQP-----LIQRDPFTSLIQVNFSKALV 676

  Fly   663 TICEQAQHFE-RLGLGVPGMVRKIYEKHETLRFVYNSVVQVCLNYNHILSALSEQERKLFRALIQ 726
            .:..:.::.. :....:|....|::.::||.|....::..:...||.|.:.:.:.|..|.::.::
Mouse   677 AVLREVKYLNFQQQKEIPESAEKLFSENETFRKFVGNLELIVGWYNEIKTTVKDVEFPLIKSELE 741

  Fly   727 ACDRKIAPGVFKLTYGGELSDAYIADCAKHTNKLQETMDIYKRAIQNIARFCEKICDTPMLKFNF 791
            |.|.|:......|.:.||....||.:..:....||..:...|:.::.|.:..::....|:.:..
Mouse   742 AIDVKLLSAETTLFWNGENVMEYIQEMREMLYNLQNRIQKAKQNVEGITQAMQEWSANPLFERK- 805

  Fly   792 SGAVTISIFENHLSSYL---RRVSNILRGFYSTITDLIFAVFKEFQAVIEDMPIE---------- 843
                     :|...:.|   .||:|:.:.         :|..||....|:.|.:|
Mouse   806 ---------DNKKEALLDLDGRVANLNKR---------YAAVKEAGVRIQAMVVENAELFRADTT 852

  Fly   844 ---WYGFVNVFDDMLATAFLTSSKNSLNMLTNALHRDPDMAAAPILVMESDVRERCIVLTPDIDV 905
               |..:||..|.::...|....:.|||.|.:.:..|..:  ||:..:..::.:..:...|.:::
Mouse   853 SQSWKDYVNYIDTVVLDEFDRFIRKSLNYLMDNMTMDESI--APLFEIRMELDKDGLTYNPSLEM 915

  Fly   906 -----IANLLSGYIDRIHNILEQFPR-----------------------------IGIKMKLPKE 936
                 ..:|:.|.|:.::|:....||                             || .||:.:|
Mouse   916 GDEAGFLSLIEGLINDLYNVARLIPRLAKGRLNYKSDLEDITDLIEMREEVSSLVIG-AMKVAEE 979

  Fly   937 HQ--YESFSKAFLEDSESTQLICNIEAEINHEREEIDGYITFWNSHRMLWETTELEFTKRVKATQ 999
            :|  :|.:|..:::|.:                |.:..::.|  .|....|..:.:....:..|.
Mouse   980 YQDSFERYSYLWVDDLQ----------------EFMKNFLIF--GHAPTPEELDTKTDDTIPKTP 1026

  Fly  1000 MTADIFEASIEYYSAMADDISYVDAITHVY--FILMNQNYIKSSILDCIEKWQALNIKILLSHSF 1062
            .|...|:..|:.|..:.:::|..:. |.|:  ::..:....|.::|:.|::|..|..:.|.:|..
Mouse  1027 PTLAQFQQQIDSYEKLYEEVSSCEN-TKVFHGWLQCDCRPFKQTLLNTIKRWSFLFKRYLNNHVI 1090

  Fly  1063 SLIRAIYRYMRKNERKMMMVPRTLKESLLAKQFFERIIN------EVPLKQAG----FPPTLELF 1117
            :.:..:..:|.        :.||..:..|.:..::.::.      :|..:|..    |.|..:..
Mouse  1091 NSLADLESFMN--------ITRTALKKPLKEGDYDGLVEVMGHLMKVKERQVATDSMFEPLKQTI 1147

  Fly  1118 AILDKYQVEIPEEIRVKVIGLEAAWHHYLKRLG----------EADEMLDNNREEFKKILVQQAE 1172
            .:|..|..|:||||.:|:..|...|.: .|:|.          :|:|:         .||.::.:
Mouse  1148 ELLKSYGEEMPEEIYLKLQELPEQWTN-TKKLAIQVKQNVAPLQANEV---------NILRRKCQ 1202

  Fly  1173 KFKIILKEFLDDFFLKLPTSANINPRIALKFLRIIALKIEDCFTFEESLMRDLAVFNVNQPESID 1237
            :|::...||.:.|....|.|.: :|. ..|.|......|.......|:|.:..::|.|..|:...
Mouse  1203 QFELKQHEFREKFRRDAPFSFS-DPE-PYKSLNKQQKSISAMEGVMEALCKSASLFEVTVPDYKQ 1265

  Fly  1238 LRKLDFEVRIVKNIWELIFEWQTNWEGWKKGYFWKMNINEMEDTALNLYKEFTTLNKKFYDRHWE 1302
            |:....|||::|.:|::|....|:.:.||...:..:|:.:|:.......|:..:|:|:.  :.|:
Mouse  1266 LKACHREVRLLKELWDMIVMVNTSIDDWKTTKWKDINVEQMDIDCKKFAKDVRSLDKEM--KPWD 1328

  Fly  1303 M---LEATTKNVDSFRRTLPLITALKNPCMRERHWNRVRDVIHVNFDENSKNFTLELIINLDFQA 1364
            .   |:.|.||:.:   :|..::.|:||.:|:|||.::.....|.| |.|:..||..::.|:...
Mouse  1329 AFVGLDNTVKNMIT---SLRAVSELQNPAIRDRHWQQLMQATQVKF-EMSEETTLADLLQLNLHK 1389

  Fly  1365 FSEDIQDISNPATMELQIENSIKNIATIWKKQSFEMAFY-HDGIYRIKNVEDCFQLLEEHMVQIS 1428
            :.:::::|.:.|..|..:|..:|.:...|....||...: ..|...:|:.|...:.||::.||:.
Mouse  1390 YEDEVRNIVDKAVKESGMEKVLKTLDITWTTMEFEHELHPRTGTMMLKSDEVLVETLEDNQVQLQ 1454

  Fly  1429 AMKATRFVEPFITIVDYWEKTLSYISETLEKGLTVQRQWLYLENIFQG-DDIRKQLPEEAKRFAT 1492
            .:..::::..|:..|..|::.||.....:.....|||.|.:||:||.| :|||.||||::|||..
Mouse  1455 NLMMSKYLSHFLKEVTSWQQKLSTADSVISIWFEVQRTWSHLESIFIGSEDIRAQLPEDSKRFDA 1519

  Fly  1493 ITEEFRTISSKMFQAKTAVKATNLRPPPFLLNRFSRMDERLELIQRALEIYLEAKRQLFPRFYFI 1557
            |.:||:.:.....:....|:|||   .|.|.|:...:...|.:.::||..|||.||..||||||:
Mouse  1520 IDQEFKALMEDAVKTPNVVEATN---KPDLYNKLENLKMSLAVCEKALAEYLETKRLAFPRFYFV 1581

  Fly  1558 SNDDLLEILGNSKRPDLVQTHLKKLFDNLYKLE--LKRVGKTLSRWQASGMHSDDGEYVEFMMVI 1620
            |:.|||:||.|...|..|..||.||||:|.||:  |...||.|.  ...||:|.:.|:|:|....
Mouse  1582 SSADLLDILSNGNDPVEVSRHLSKLFDSLCKLKFRLDASGKPLK--FGLGMYSKEDEFVDFDKEC 1644

  Fly  1621 YIDGPSERWLKQVEEYMLVVMKEMLKLTRGSLKKLVGNREKWISLWPGQMVLTTAQIQWTTECTR 1685
            .:.|..|.||.:|.:.|...::.  ::....:......||:||..:|.|:.||..||.||||.
Mouse  1645 DLSGQVEVWLNRVLDRMRATLRH--EIPEAVVTYEEKPREQWIFDYPAQVALTCTQIWWTTEV-- 1705

  Fly  1686 SLIHCSMVD-QKKPLRKLKKKQIKVLSKLSEMSRKDLTKTMRLKVNTLITLEIHGRDVIERMYKS 1749
            .|....:.: .:..::...||||..|:.|..:...:||...|:|:.|:.|:::|.|||:.:|..:
Mouse  1706 GLAFARLEEGYENAIKDYNKKQISQLNALITLLIGNLTAGDRMKIMTICTIDVHARDVVAKMITA 1770

  Fly  1750 NCKDTGHFEWFSQLRFYWHRESELCVIRQTNTEHWYGYEYTGNSGRLVITPLTDRCYITLTTALH 1814
            ..:.:..|.|.||||..|..|.:.|.....:.:..|.|||.||:.||||||||||||||||.:||
Mouse  1771 KVESSQAFTWQSQLRHRWDEEKKHCFANICDAQIKYSYEYLGNTPRLVITPLTDRCYITLTQSLH 1835

  Fly  1815 LHRGGSPKGPAGTGKTETVKDLGKALGIWVIVTNCSEGLDYKSIGKNFSGLAQSGCWGCFDEFNR 1879
            |..||:|.||||||||||.||||:|||..|.|.||||.:||||.|..:.||||:|.|||||||||
Mouse  1836 LIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNR 1900

  Fly  1880 INIEVLSVVAQQIMSIMAALSTKALELMFEGQMIKLKHTVGLFITMNPGYAGRTELPDNLKSMFR 1944
            |::|||||:|.|:..:..|:..|..:..|.|::|.|..|||:|||||||||||||||:|||::||
Mouse  1901 ISVEVLSVIAVQVKCVQDAIRAKKKKFNFLGEIISLVPTVGIFITMNPGYAGRTELPENLKALFR 1965

  Fly  1945 PISMMVPDNIIIAENLLFSDGFTNTRNLARKVYTLYELAKQQLSKQYHYDFGLRSMVALLRYAGR 2009
            |.:|:|||..:|.|.:|.::||.:.|.||||..|||.|.|:.||||.|||:|||::.::|..||.
Mouse  1966 PCAMVVPDFELICEIMLVAEGFLDARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGS 2030

  Fly  2010 KRRQLPNTTEEEIVYLAMKDMNVARLTANDLPLFNGIMSDIFPGVSLPTIDYSEFNIAIYEEFRE 2074
            .:|..|...|::::..|::|.|:.::..:|||:|.|::.|:||.:.:|......|...|.:...|
Mouse  2031 LKRGDPTRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQSIVE 2095

  Fly  2075 AGLQPITIAVKKVIELFETKNSRHSVMIIGDTGTAKSVTWRTLQNCFYRMNSQRFSGWEAVTVYP 2139
            ..||.....|.||::|.|....||||.:||:.|:.||...::|...:  .|.:|    :.|.| .
Mouse  2096 LKLQAEDSFVLKVVQLEELLQVRHSVFVIGNAGSGKSQVLKSLNKTY--QNLKR----KPVAV-D 2153

  Fly  2140 VNPKALNLAELYGEYNLSTGEWLDGVLSSIMRIICGDEEPTQKWLLFDGPVDAVWIENMNSVMDD 2204
            ::|||:...||:|..|.:|.||.||:.|:|||.:........||::.||.:|.:|||::|:||||
Mouse  2154 LDPKAVTCDELFGIINPATREWKDGLFSTIMRDLANLTHEGPKWIVLDGDIDPMWIESLNTVMDD 2218

  Fly  2205 NKLLTLVNSERITMPVQVSLLFEVGDLAVASPATVSRCGMVYNDYNDWGWKPFVNSWLQRLRIKE 2269
            ||:|||.::|||.:...:.|:||:..|..|:||||||.|::|.:..|.||.|.|:||::|.:::.
Mouse  2219 NKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIERRKVQS 2283

  Fly  2270 FADFLRIHFDYMVPKILDFKRMRCKEPVRTNELNGVVSLCKLLEIFGTKVNGINPINLELLEEMT 2334
            ....|.|.||..:|..||..|:..|......|:..:.::..|||...|:.|.......||.|
Mouse  2284 EKANLIILFDKYLPTCLDKLRIGFKRITPVPEITVIQTILYLLECLLTEKNAPPDSPKELYE--- 2345

  Fly  2335 RLWFMFCLVWSICSSVDEDSRQRLDS-------FIRELESC-FPIKDTVFDYFVDPNERTFLPWD 2391
             |:|:|...|:...::.:|  |.:|.       :|.|.::. .|.:.|:|||::||..:.||||.
Mouse  2346 -LYFVFACFWAFGGAMFQD--QLIDYRVEFSKWWINEFKTIKLPSQGTIFDYYIDPETKKFLPWT 2407

  Fly  2392 SKLLSSWKCDFESPFYKIIVPTGDTVRYEYVVSKLLAEEYPVMLVGNVGTGKTSTAISVMEACDK 2456
            .| :.:::.|.:.|....:|.|.:|:|..|.:..|:.:.:|||||||.||||:......:|....
Mouse  2408 DK-VPNFELDPDIPLQASLVHTTETIRIRYFIDLLMEKAWPVMLVGNAGTGKSVLMGDKLENLST 2471

  Fly  2457 NKFCILAVNMSAQTTAAGLQESIENRTEKRTKTQFVPIGGKRMICFMDDFNMPAKDIYGSQPPLE 2521
            :.:.:.||..:..||:|.||..:|...||::...:.|.|.|::|.|:||.|||..|.||:..|..
Mouse  2472 DDYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLIYFIDDMNMPEVDKYGTVAPHT 2536

  Fly  2522 LIRQWIDYKYWFNRKTQQKIYVQNTLLMAAMGPPGGGRQTISSRTQSRFVLLNLTFPSQETIIRI 2586
            ||||.:|:::|::|:......|.|...:|.|.|..|. .||..|.|..|.:..::||.||.:..|
Mouse  2537 LIRQHMDHRHWYDRQKLTLKDVHNCQYVACMNPTSGS-FTIDPRLQRHFCVFAVSFPGQEALTSI 2600

  Fly  2587 FGTMLCQKL--ESYPNEVREMWLPITLCTINLYVSMISKMLPTPNKSHYLFNLRDISKVFQGLLR 2649
            :.|:|.|.|  .|.|..::.:...:....:.|:..:.:..|||..|.||:|||||:|.:|||:|.
Mouse  2601 YNTILAQHLSFRSAPLVIQRLSSHLVTAALALHQKVSATFLPTAIKFHYIFNLRDLSNIFQGILF 2665

  Fly  2650 SEKELQNKKNFFLRLWVHECFRVFSDRLVDDSDQFWFVNTINDILGKHFEVTFHSLCPSKVPPFF 2714
            |..|:.......:|||:||..||:.|::||:.||                .|.|.:..:.|..||
Mouse  2666 STAEILKTPLDLVRLWLHEAERVYGDKMVDEKDQ----------------ETLHRVTIASVKKFF 2714

  Fly  2715 GD------FAHP-------QG-----FYEDLQVDFLRTFMKNQLEEYNNFPGMTRMNLVFFREAI 2761
            .|      ||.|       ||     ::....|..|...:|:.|:.||....:  ||||.|.:|:
Mouse  2715 DDLGEENLFAKPNIFCHFTQGIGDPKYFPVTDVAQLNKLLKDVLDSYNEVNAV--MNLVLFEDAV 2777

  Fly  2762 EHIVRILRVISQPRGHILNMGIGGSGRQVLTKLAAFILEMAVFQIEVTKKYKTGDFREDLKNLYK 2826
            .||.:|.|::..|||:.|.:|:||||:|.|::|||:|..:.||||.:.|.|...|.:.||...|.
Mouse  2778 AHICKINRILESPRGNALLVGVGGSGKQSLSRLAAYISALDVFQITLKKGYAIPDLKMDLATQYI 2842

  Fly  2827 VTGIKQRLTIFIFSSDQIAEVSFLEITNNMLSTGEI-NLFKSDEFDELKPELERPAKKNGVLLTT 2890
            .:.:|...::|:.:..|:||..||.:.|::|::||| .||..::.:.:...:....|..|:..|.
Mouse  2843 KSAVKNVPSVFLMTDSQVAEEQFLVLINDLLASGEIPGLFGDEDLENIISSMRPQVKSLGIADTR 2907

  Fly  2891 EALYSYFILNVRDFLHVALCFSPIGENFRSYIRQYPALLSSTTPNWFRFWPQEALLEVASHFLIG 2955
            ||.:.:||..||..|.|.|||||:|...|...|::||:::.|..|||..||::||:.|::.||
Mouse  2908 EACWKFFIEKVRRQLKVILCFSPVGSVLRVRARKFPAVVNCTAINWFHEWPEDALVSVSARFL-- 2970

  Fly  2956 FPLNVVVSGKEDEKHRESLVISTEAILQRDIAYVFSVIHSSVAKMSENMYAEVKRYNYVTSPNYL 3020
                     :|.|        ..|..::..|:...:.:|::|.:||:......:||||.|...:|
Mouse  2971 ---------EETE--------GIEPEVKTSISLFMAYVHTTVNEMSKIYLTIERRYNYTTPKTFL 3018

  Fly  3021 QLVSGFKKLLEKKRLEVSTASNRLRNGLSKISETQEKVSLMSEELKASSEQVKILARECEDFISM 3085
            :.:..::.||.|||:|:.....||.|||.|:..|..:|..:..:|.....::|......:..|.:
Mouse  3019 EQIKLYQNLLAKKRMELVAKIERLENGLMKLQSTASQVDDLKAKLAVQETELKQKNENADKLIQV 3083

  Fly  3086 IEIQKSEATEQKEKVDAEAVLIRRDEII---CLELAATARADLEVVMPMIDAAVKALDALNKKDI 3147
            :.::..:.:::|...|.|.:.:   |:|   ..|.......||....|.:.||.:|||.|||.::
Mouse  3084 VGVETEKVSKEKAIADEEEMKV---EVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNL 3145

  Fly  3148 SEVKSYGRPPMKIEKVMEAVLIL------LGKEPTWENAKKVLSE-STFLNDLKNFDRDHISDKT 3205
            :|:||:|.||..:..|..||:||      :.|:.:|:.||.::.: .|||:.||.||::||.:..
Mouse  3146 TELKSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEAC 3210

  Fly  3206 LKRIAIYTKNPELEPDKVAVVSLACKSLMQWIMAIENYGKVYRIVAPKQEKLDSAMKSLEEKQAA 3270
            ||....|..||..:|:.:...|.|...|..|.:.|..:.:||..||||::.|:.|...|.|.|..
Mouse  3211 LKAFKPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEK 3275

  Fly  3271 LAAAKKKLEELQVVIEELYRQLEEKTNLLNELRAKEERLRKQLERAIILVESLSGERERWIETVN 3335
            |:..|.|:.||...:..|....|:.|....:.:.:.:...:.:..|..||..|:.|..||.|:|.
Mouse  3276 LSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEADATNRVISLANRLVGGLASENVRWAESVE 3340

  Fly  3336 QLDLSFEKLPGDCLLSVAFMSYLGAFDTKYREELLVK-WSLLIKDLL--IPATLELKVTYFLVDA 3397
            ........|.||.||..||:||:|.|..|||.||:.| |...|..|.  ||.|..|.....|.|.
Mouse  3341 NFKSQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYINKLKVPIPITEGLDPLTLLTDD 3405

  Fly  3398 VSIREWNIQGLPADDLSTENGVIVTQGSRWPLIIDPQMQANNWIKNMEERNQLMTLDFGMADYLR 3462
            ..:..||.||||:|.:||||..|:....|||||:|.|:|...|||| :..:.|..:..|...||.
Mouse  3406 ADVATWNNQGLPSDRMSTENATILCNTERWPLIVDAQLQGIKWIKN-KYGSDLQAIRLGQKSYLD 3469

  Fly  3463 QLERALKEGLPVLLQNVGEYLDQAINPILRQSFTIQSGERLLKFNDKYISYNNSFRFYITTKISN 3527
            .:|:|:..|..:|::|:||.:|..::|:|.:: ||:.| |.:|..||.:.|:.|||..:.||..|
Mouse  3470 IIEQAISAGDTLLIENIGETVDPVLDPLLGRN-TIKKG-RFIKIGDKEVEYHPSFRLILHTKYFN 3532

  Fly  3528 PHYPPEISSKTTIVNFALKQDGLEAQLLGIIVRKEKPALEEQKDELVMTIARNKRTLIDLDNEIL 3592
            |||.||:.::.|::||.:.:||||.|||..:|.||:|.||:.|..|..:....|..|.:|::.:|
Mouse  3533 PHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLKELEDSLL 3597

  Fly  3593 RLLNESRGSLLDDDELFSTLQKSRQTSVLVKESLSIAEVTEVEIDAARQEYKPASERASILFFVL 3657
            ..|:.:.|:.|.|..|...|:.::.|:..::|.:..|::|||:|:.||:.|:||:||||:|:|:|
Mouse  3598 ARLSAASGNFLGDTALVENLETTKHTANEIEEKVQEAKITEVKINEARENYRPAAERASLLYFIL 3662

  Fly  3658 MDMSKIDPMYVFSLAAYILLFTQSIERSPRNQLVHERIQNINEYHSYAVYRNTCRGLFERHKLLF 3722
            .|::||:|:|.|||.|:.::|.::|:::.....|.:|:.|:.:..:|:||..|.||||||.||:|
Mouse  3663 NDLNKINPIYQFSLKAFNVVFEKAIQKTAPADEVKQRVINLTDEITYSVYMYTARGLFERDKLIF 3727

  Fly  3723 SIHMTAKILSNAGKLLEEEYDFIL----KGGIVLDKLGQAPNPAPWWISEQNWDNITELDKVSGF 3783
            ...:|.::||...:|...|.||:|    |.|:|        :|.. ::..|:|..|..|.::..|
Mouse  3728 LAQVTFQVLSMKKELNPVELDFLLRFPFKAGVV--------SPVD-FLQHQSWGGIKALSEMDEF 3783

  Fly  3784 HGIIDSFEQHYKAWNGWYATTFPEQEDLVGEWNDKLTDFQKICVLRSLRPDRISFCLTQFIITKL 3848
            ..:....|...|.|.....:..||:|....||.:| |..||:|::|.:||||:::.:..|:..|:
Mouse  3784 KNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNK-TALQKLCMVRCMRPDRMTYAVKNFVEEKM 3847

  Fly  3849 GPRYVDPPVLDLKATFDESISQTPLIFVLSPGVDPAQSLISLSESVKMA---QRMYSLSLGQGQA 3910
            |.::|:...::...::.||...||:.|:|||||||.:.:.:|.:.:...   .:::::||||||.
Mouse  3848 GSKFVEGRSVEFSKSYKESSPSTPIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQE 3912

  Fly  3911 PIATKLIMDGIKDGNWVFLANCHLSLSWMPTLDKMIATMQSMKLHKKFRLWLSSSPHPD-----F 3970
            .:|...:....:.|:||.|.|.||...|:..|||.:....|.. |:.:|:::|:.|.|.     .
Mouse  3913 VVAENALDVAAEKGHWVILQNIHLVARWLGILDKKVERYSSGS-HEDYRVFISAEPAPTAETHII 3976

  Fly  3971 PISILQTSIKMTTEPPRGIKSNMKRLYNNINEANMENCSEPSKYKKLLFALCFFHTVLLERKKFL 4035
            |..||:.:||:|.|||.|:.:|:.:..:...:..:|.|::..::|.:|||||:||.|:.||:||.
Mouse  3977 PQGILENAIKITNEPPTGMYANLHKALDLFTQDTLEMCTKEIEFKCILFALCYFHAVVAERRKFG 4041

  Fly  4036 ELGWNVIYSFNDSDFEVSEILLLLYLNEYEDTPWGALKYLIAGVNYGGHITDDWDRRLLITYINQ 4100
            ..|||..|.||:.|..:|..:|..||......||..|:||...:.|||||||||||||..||:.:
Mouse  4042 AQGWNRSYPFNNGDLTISINVLYNYLEANSKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAE 4106

  Fly  4101 FFCDQALQTRKFRLSTLPNYFIPDDGDVQSYLDQIQMFPNFDKPDAFGQHSNADIASLIGETRML 4165
            :...:.|:.   .:...|.:.||.:.|.:.|.:.|......:.|..:|.|.||:|..|...:..|
Mouse  4107 YIRVEMLEG---EVLLAPGFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKL 4168

  Fly  4166 FEALLSMQ-VQTNS-TSSNENGETKVFDLAKEILMNTPDEINY-EQTAKIIGINRTPLEVVLLQE 4227
            |..:|.|| .:|:| ..:..:.|.||..:..:||...|:..|. |..||  ...:||..||..||
Mouse  4169 FRTVLEMQPKETDSGAGTGVSREEKVKAVLDDILEKIPETFNMAEIMAK--AAEKTPYVVVAFQE 4231

  Fly  4228 IERYNKLLVDMSTQLRDLRRGIQGLVVMSSDLEDIYLAVSEGRVPLQWL-KAYNSLKPLAAWARD 4291
            .||.|.|..:|...|::|..|::|.:.:::|:||:..|:....||..|: :||.|:..||||..|
Mouse  4232 CERMNILTNEMRRSLKELNLGLKGELTITTDMEDLSTALFYDTVPDTWVARAYPSMMGLAAWYAD 4296

  Fly  4292 LIHRVGHFNSWAKTLRPPILFWLAAYTFPTGFVTAVLQTSARATKTPIDELSWDFYVFVE--EDT 4354
            |:.|:....||......|...|||.:..|..|:||::|:.||..:.|:|::.....|..:  ||.
Mouse  4297 LLQRIRELESWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVTKKNREDM 4361

  Fly  4355 AAARIIREGGGVYIRSLFLEGGGWLRKNQCLQDPLPMELICPLPVIHFKPVENLKKRCRGVYQCP 4419
            .|..  |||.  |:..||:||..|..:...:.:....:|...:|||..|.:...:...:.:|:||
Mouse  4362 TAPP--REGS--YVYGLFMEGARWDTQTGVIAEARLKDLTPVMPVIFIKAIPVDRMETKNIYECP 4422

  Fly  4420 AYYYPVRSGSFVIAVDLKSGNEKADYWIKRGTALLLSL 4457
            .|...:|..::|...:||: .|||..||....||||.:
Mouse  4423 VYKTRIRGPTYVWTFNLKT-KEKAAKWILAAVALLLQV 4459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kl-2	NP_001015505.5	DHC_N1	178..749	CDD:285571	130/618 (21%)
		DHC_N2	1244..1646	CDD:285579	131/408 (32%)
		P-loop_NTPase	1785..2015	CDD:304359	141/229 (62%)
		P-loop_NTPase	2099..2242	CDD:304359	59/142 (42%)
		P-loop_NTPase	2401..2668	CDD:304359	95/268 (35%)
		P-loop_NTPase	2752..3030	CDD:304359	95/278 (34%)
		MT	3043..3373	CDD:289543	108/340 (32%)
		AAA_9	3402..3618	CDD:289547	85/215 (40%)
		Dynein_heavy	3760..4447	CDD:281078	229/700 (33%)
Dnah17	XP_006534213.1	DHC_N1	187..764	CDD:369845	130/616 (21%)
		DHC_N2	1266..1672	CDD:369852	132/418 (32%)
		DYN1	1493..4124	CDD:227570	996/2711 (37%)
		AAA_6	1806..2132	CDD:372306	172/325 (53%)
		AAA_8	2768..3027	CDD:372310	95/277 (34%)
		MT	3040..3383	CDD:289543	109/345 (32%)
		Dynein_C	4162..4457	CDD:375627	97/301 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1492at2759
OrthoFinder	1	1.000	-	-		FOG0000396
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100025
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820