DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment kl-2 and Dhc93AB

DIOPT Version :9

Sequence 1:	NP_001015505.5	Gene:	kl-2 / 3355181	FlyBaseID:	FBgn0001313	Length:	4459	Species:	Drosophila melanogaster
Sequence 2:	NP_001262793.1	Gene:	Dhc93AB / 42485	FlyBaseID:	FBgn0013812	Length:	4496	Species:	Drosophila melanogaster

Alignment Length:	4636	Identity:	1414/4636 - (30%)
Similarity:	2329/4636 - (50%)	Gaps:	413/4636 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 VISIWLINSTELVLTIFYDCDVLTGCLGFPVAPVIDLCYFIRS---SKEIISIHSF------HDM 95
            :|..:|..:|.:||.|     :||     |.|.::....|..|   ||.:..|..:      .|.
  Fly    52 IIKEFLDRNTPVVLII-----ILT-----PAAQLVPSTTFPLSQLKSKGVYFIKRYALPIPREDC 106

  Fly    96 VNF---GTVQDDVDGCLLKILELIYAPIFR---NFMEWGDNVKQRFCTSLDKFLGILTAIYFKMS 154
            .||   |.:.......|..::|.:..|:..   |:..|...|.|.....:......:..:..::|
  Fly   107 GNFIIYGDLATRTIDQLSALVEEVLVPLLSNEDNYRNWPIMVAQDVQKHVHSLKSTVHQVKGQVS 171

  Fly   155 GMTVLYVPYVVKEIAK--------EISSYDREFVKNLECIAVSWATLIRILLNDKTLTSPNEYIS 211
            |.|:|.:|..|::|.|        |...:|......:|.:.:.|||.|..::.:    ||:...:
  Fly   172 GETILAMPVGVEKIVKAAKELVETEQCQFDLYLKSAIEGVVIKWATQIHEVIKE----SPSNAFA 232

  Fly   212 VGD------EFEFWLYRFEVLQGLNAQLDQVDVQQIIRVLRSTHSVYIKQIDELIFESTHELMEA 270
            .|.      ||.||..|.:.|..:..||....::.:..:|..:.|.|......|.......|.||
  Fly   233 NGQNPTPHTEFTFWNNRLKNLSFIYDQLRNERIRAMALILEYSMSAYHPCFQTLFKNVVTALAEA 297

  Fly   271 MENIKFLHLLMQP---CSQLDFSESPTFVSQLIPRTIHLIRFIWLNSEQYNRRDLITGIFRNLSN 332
            .:...:|:.|.:|   ..::||:|....   ||| .::.:..:|.||..|.:...||.:.:.:.|
  Fly   298 KDITLYLNPLKRPLQHLEEIDFAECKPL---LIP-FMNTVGILWGNSRYYCQSAKITVLLQEICN 358

  Fly   333 QIIRFCTEKVNVEKILSGSSRFGIKICNMCIDCCLTYKGIYDIMSK------THAKINIRIGWSL 391
            .||......::...|........::...:.|.....::.::|...:      |..:....|.|:.
  Fly   359 LIIHQAKRYLDPSSIFHSDIDEAMQRLTLSIQILKFFRELFDYYKERLATFFTEPEERPPILWTF 423

  Fly   392 DNAMIFNHVDAFMERLNDVIDICESMMVFGRLDESESIPKPQFGGTSGTEFEATADNVENEFLVT 456
            ....:|...:||:|||..:      ...|..:.|...:.|.:.||..|.:......:|..||...
  Fly   424 HPNSVFKRFNAFLERLTTI------QWFFFTVIEFLKLEKVEIGGLRGRQLSTRITDVYVEFNQY 482

  Fly   457 LTALCTDSKEIILNVHKNEWYEEVIKYRRTVQSMEETVQRLMSNVFQHICNVEEALESLNVMIFY 521
            .||..:.|.: :|:...:|:.|:...::..:..::..:..::...|....|:|...:.::::...
  Fly   483 FTAFASKSYD-VLDPDDHEFDEDFKGFQTRILELDMKLAAILCQAFDDCHNLESIFKLISIVGSV 546

  Fly   522 SYRSTIRKTFLRQVSSAWVFFSNEI---DSSVHMLMDRSKMHESWVPYYASRALGYRVHLDRLVW 583
            ..|..|::.|.::.:.......:|:   :|.....|:..|:.::..|.|....:...:.     |
  Fly   547 LDRPKIKEEFTQRYAEIVRMLDDEMTICESIYDKQMELKKVGDNLYPNYNCPPVAAFIR-----W 606

  Fly   584 LCNRLNSSDWLPNVSEASVVLKKFESVRREFDKEVKKS--------------------FDEWQKN 628
             |::|.:....|        :|.|::::.|..|..|..                    ||:|...
  Fly   607 -CHQLETRITAP--------VKNFKALQHEITKTEKSQEIVERYEILMVKLGSCKTQFFDDWAGQ 662

  Fly   629 CCSLLLNQKLDRYLLIRSKKKKGLIECNIDRTILTICEQAQHFERLGL-GVPGMVRKIYEKHETL 692
            ... .:.:.|.:.|:.|.::...|| .|....:.:|..:..:.:::.: |:|.:.....||.:..
  Fly   663 LDG-QIEENLKKSLIARDRRHNSLI-LNFSAALFSILREVHYMQQMKIEGIPQIAIDFAEKSDVF 725

  Fly   693 RFVYNSVVQVCLNYNHILSALSEQERKLFRALIQACDRKIAPGVFKLTYGGELSDAYIADCAKHT 757
            |....::.:....||.|....|..|.:|....|:..|..:..||.:|.:......:|:....|..
  Fly   726 RSYTLNLEKTIDWYNSIQEGSSPVELRLIEPEIKMIDDLVEIGVNQLVWNSSDILSYLDKLRKPV 790

  Fly   758 NKLQETMDIYKRAIQNIARFCEKICDTPMLKFNFSGAVTISIFENHLSSYLRRVSNILRGFYSTI 822
            ..||..||..:..::.|.:........|:.:.......|:...:.......:|.:.|.
  Fly   791 AALQNRMDHTQGNLRQIRKIMGVWAKQPLFERRDCKKDTVLSIDERPDRTSKRYAEIQ------- 848

  Fly   823 TDLIFAVFKEFQAVIEDMPIE-----------WYGFVNVFDDMLATAFLTSSKNSLNMLTNALHR 876
                 |...|...:::|..::           |..:|:..|:::....|.:...|:..|  |.:.
  Fly   849 -----AASIEIHKLLQDNMLQFDMESKQDDAVWLSYVDFVDNIVYENILKTVGVSVGYL--AENM 906

  Fly   877 DPDMAAAPILVMESDVRERCIVLTPDIDVIANLLSGYIDRIHNILEQFPRIGIKMKLPKEHQYES 941
            ||:...||:.....::.|..:|..|.:|....:  |:.:.:..::....::|..:|..|.::..:
  Fly   907 DPENNYAPLFESRLELVEPNLVFVPSLDPEDPM--GFNNMLIELMRDIMKMGSLIKRLKPNEKRN 969

  Fly   942 FSKAFLEDSESTQLICNIEAEINHEREEIDGYITFWNSHRMLW-----ETTE--LEFTKRV---- 995
            :.:...|:.:...:...|...::...||...:...:..:..||     |..|  ||:.:.:
  Fly   970 YVEMIKENQDIIDMRREILNGVDLVMEEASRFCRQFERYSYLWLDDREECMEYFLEYGRMLDPDE 1034

  Fly   996 --------------KATQMTADIFEASIEYYSAMADDISYVDAITHVY--FILMNQNYIKSSILD 1044
                          :..|.|.:.|...|:.|.::.::|..:... .|:  :..::....:.::|:
  Fly  1035 IELILINDPNQPPPQPCQPTIEAFREQIDNYESLFNEIEDIGPF-QVFSSWFQVDVRPFRQALLN 1098

  Fly  1045 CIEKWQALNIKILLSHSFSLIRAIYRYMRKNERKMMMVPRTLKE-------SLLAKQFFERIINE 1102
            .:.||..:..:.|::...|.:..:..::||.:..::   :|:||       |::|  :..::...
  Fly  1099 TVCKWGNMFKEHLVTTVTSSLMNLSHFIRKADEGLL---QTVKEKDYEGLVSIMA--YLMQVKER 1158

  Fly  1103 VPLKQAGFPPTLELFAILDKYQVEIPEEIRVKVIGLEAAWHHYLKRLG----------EADEMLD 1157
            .......|.|..|...:|..|.::||||:.|.:..|...|.: .|::.          :|.|::.
  Fly  1159 AAKTDEMFEPMQETIQLLKYYDMDIPEEVNVLLQELPEQWAN-TKKIASTVKQQVSPLQATEVVS 1222

  Fly  1158 NNREEFKKILVQQA--EKFKIILKEFLDDFFLKLPTSANINPRIALKFLRIIALKIEDCFTFEES 1220
            ..    .||.:.::  :.|:.:.|.:  |||           |.......::..:|.|.....||
  Fly  1223 IR----NKIALFESHIQLFREVFKTY--DFF-----------RFDCYKPYLLMDRINDDMFLCES 1270

  Fly  1221 LMRDL----AVFNVNQPESIDLRKLDFEVRIVKNIWELIFEWQTNWEGWKKGYFWKMNINEMEDT 1281
            .|||:    ::|.||.||...|::...|:|::|.:|:.:....|:.:.||...:.|:::..|:..
  Fly  1271 EMRDIQESGSLFEVNIPEFKVLKQCRKELRMLKQLWDYVNIVATSIDDWKTTPWRKVDVENMDIE 1335

  Fly  1282 ALNLYKEFTTLNKKFYDRHWEM---LEATTKNVDSFRRTLPLITALKNPCMRERHWNRVRD---- 1339
            .....|:...|:|:.  |.|:.   ||:|.||:   ..:|..:..|:||.:||||||::.:
  Fly  1336 CKKFAKDIRLLDKEM--RPWDTFINLESTVKNM---LTSLRAVGELQNPAIRERHWNQLMNSTKS 1395

  Fly  1340 ------VIHVNFDENSKNFTLELIINLDFQAFSEDIQDISNPATMELQIENSIKNIATIWKKQSF 1398
                  .:.|.|..:.:. ||..::.|:.....|::::|.:.|..|:.:|..::::.|.|....|
  Fly  1396 LAALPKEVTVKFIMDHET-TLAELLGLNLHECEEEVKNIVDKAVKEMSMEKILRDLNTTWTVMEF 1459

  Fly  1399 EMAFY-HDGIYRIKNVEDCFQLLEEHMVQISAMKATRFVEPFITIVDYWEKTLSYISETLEKGLT 1462
            :...: ..|...:|..|:..:.||::.|.:..:..::::..|:..|..|:..|....:.:.....
  Fly  1460 DHELHPRTGCNLLKASEELIETLEDNQVCLQNLITSKYIAHFLEEVSTWQNKLMIADQVITVWFE 1524

  Fly  1463 VQRQWLYLENIF-QGDDIRKQLPEEAKRFATITEEFRTISSKMFQAKTAVKATNLRPPPFLLNRF 1526
            |||.|.:||:|| ..:|||||||.::.||..|..|||.:..:|..:...|.:||...   |:.|.
  Fly  1525 VQRTWTHLESIFMSSEDIRKQLPVDSDRFDNIDAEFRVLMDEMSVSSNVVASTNRSG---LIERL 1586

  Fly  1527 SRMDERLELIQRALEIYLEAKRQLFPRFYFISNDDLLEILGNSKRPDLVQTHLKKLFDNLYKLEL 1591
            ..:.:.|.|.::||..|||.||..||||||:|:.|||::|.|..:|::|..||.||||::.:|:.
  Fly  1587 EHLQKELTLCEKALAEYLETKRLAFPRFYFVSSADLLDVLSNGIQPEMVTKHLTKLFDSIARLKF 1651

  Fly  1592 KRVGKTLSRWQASGMHSDDGEYVEFMMVIYIDGPSERWLKQVEEYMLVVMKEMLKLTRGSLKKLV 1656
            .| .::.....||||::.|||||||..:..|.||.|.||.:::..|           |.||:..|
  Fly  1652 NR-DESNEINTASGMYAKDGEYVEFNELASIRGPVEVWLNRIQAAM-----------RASLRHYV 1704

  Fly  1657 ---------GNREKWISLWPGQMVLTTAQIQWTTECTRSLIHCSMVDQ--KKPLRKLKKKQIKVL 1710
                     ..||:|:..:|.|:.|..:||.|:||..   |..|.:::  ...::...||||..|
  Fly  1705 MEAVIAYEEKQREQWLFDYPAQVSLCGSQIWWSTEVN---IAFSRLEEGYDNAIKDYYKKQISQL 1766

  Fly  1711 SKLSEMSRKDLTKTMRLKVNTLITLEIHGRDVIERMYKSNCKDTGHFEWFSQLRFYWHRESEL-- 1773
            |.|..:...:|:|..|.|:.|:.|:::|.|||:.:|.::.......|.|.||||   ||..::
  Fly  1767 SLLITLLLGELSKGDRQKIMTICTIDVHSRDVVAKMIQAKLDSGSAFMWQSQLR---HRFDDVEK 1828

  Fly  1774 -CVIRQTNTEHWYGYEYTGNSGRLVITPLTDRCYITLTTALHLHRGGSPKGPAGTGKTETVKDLG 1837
             |.....:.|..|.:||.||:.||||||||||||||||.:|||..||:|.||||||||||.||||
  Fly  1829 DCFANICDAEFQYCHEYLGNTPRLVITPLTDRCYITLTQSLHLVMGGAPAGPAGTGKTETTKDLG 1893

  Fly  1838 KALGIWVIVTNCSEGLDYKSIGKNFSGLAQSGCWGCFDEFNRINIEVLSVVAQQIMSIMAALSTK 1902
            :|:||.|.|.||||.:||:|.|..:.||||:|.||||||||||.:|||||||.|:.|:..|:..|
  Fly  1894 RAIGISVYVFNCSEQMDYQSCGNIYKGLAQTGAWGCFDEFNRITVEVLSVVAVQVKSVQDAIRDK 1958

  Fly  1903 ALELMFEGQMIKLKHTVGLFITMNPGYAGRTELPDNLKSMFRPISMMVPDNIIIAENLLFSDGFT 1967
            ..:..|.|:||....|||:|||||||||||||||:|||::|||.:|:|||..:|.|.:|.::||.
  Fly  1959 KDKFNFMGEMISCVPTVGIFITMNPGYAGRTELPENLKALFRPCAMVVPDFELICEIMLVAEGFQ 2023

  Fly  1968 NTRNLARKVYTLYELAKQQLSKQYHYDFGLRSMVALLRYAGRKRRQLPNTTEEEIVYLAMKDMNV 2032
            :.|.||||..|||.|.|:.||||.|||:|||::.::|..||..:|..|...|||::..|::|.|:
  Fly  2024 DARVLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPGRPEEEVLMRALRDFNI 2088

  Fly  2033 ARLTANDLPLFNGIMSDIFPGVSLPTIDYSEFNIAIYEEFREAGLQPITIAVKKVIELFETKNSR 2097
            .::..:|:|:|.|::||:||.:.:|.....:|...:.:...:..|||....:.||::|.|....|
  Fly  2089 PKIITDDMPVFMGLISDLFPALDVPRKRDQDFERTVKQAASDLLLQPEDNFILKVVQLEELLEVR 2153

  Fly  2098 HSVMIIGDTGTAKSVTWRTLQNCFYRMNSQRFSGWEAVTVYPV----NPKALNLAELYGEYNLST 2158
            |||.|:|:.||.|:..|:||...:..:..:           |:    ||||:...||:|..|.:|
  Fly  2154 HSVFIVGNAGTGKTQVWKTLLRTYQNIKRK-----------PIFNDLNPKAVTNDELFGIINPAT 2207

  Fly  2159 GEWLDGVLSSIMR---IICGDEEPTQKWLLFDGPVDAVWIENMNSVMDDNKLLTLVNSERITMPV 2220
            .||.||:.|.:||   .|.||:   .||::.||.:|.:|||::|:||||||:|||.::|||.:..
  Fly  2208 REWKDGLFSVLMRDQANITGDQ---PKWIVLDGDIDPMWIESLNTVMDDNKVLTLASNERIALTP 2269

  Fly  2221 QVSLLFEVGDLAVASPATVSRCGMVYNDYNDWGWKPFVNSWLQRLRIKEFADFLRIHFDYMVPKI 2285
            .:.||||:.:|..|:||||||.|::|.:..|.||.|:|.||::..:|......|.:.||..:|..
  Fly  2270 SMRLLFEISNLRTATPATVSRAGILYINPQDLGWNPYVTSWVETRKIPAEKSNLVMLFDKYIPPS 2334

  Fly  2286 LDFKRMRCKEPVRTNELNGVVSLCKLLEIFGTKVNGINPIN--LELLEEMTRLWFMFCLVWSICS 2348
            |:..|:|.|:.....|:..:..||.||..|      :.|.|  .:..:|...|:|:|..:|:..|
  Fly  2335 LETIRVRFKKITPVAEMAHIQMLCHLLNCF------LIPANTPADCPKEWHELYFVFACIWAFGS 2393

  Fly  2349 SVDEDSRQRLDS-------FIRELESC-FPIKDTVFDYFVDPNERTFLPWDSKLLSSWKCDFESP 2405
            ::.:|  |.:|.       ::.|.::. ||...||||||:|...:|||||..| :..::.|.:.|
  Fly  2394 AMFQD--QAIDYRVEFSKWWVNEFKTVKFPPGGTVFDYFLDSETKTFLPWTEK-IPKFELDSDLP 2455

  Fly  2406 FYKIIVPTGDTVRYEYVVSKLLAEEYPVMLVGNVGTGKTSTAISVMEACDKNKFCILAVNMSAQT 2470
            ...:||.|.:::|..:.:..|:.:::|||||||.|.|||......:::..:| :.:..:..:..|
  Fly  2456 LQAVIVHTSESIRLRFFLDLLMDKKHPVMLVGNAGCGKTVLVNEKLQSLSEN-YAVTTIPFNYYT 2519

  Fly  2471 TAAGLQESIENRTEKRTKTQFVPIGGKRMICFMDDFNMPAKDIYGSQPPLELIRQWIDYKYWFNR 2535
            |:..||:.:|...||:....:.|.|.|.:..|:||.|||..|.||:..|..|:||.:||.:|::|
  Fly  2520 TSEMLQKILEKPLEKKAGRNYGPPGNKLLCYFVDDINMPEVDAYGTVQPHTLMRQHLDYGHWYDR 2584

  Fly  2536 KTQQKIYVQNTLLMAAMGPPGGGRQTISSRTQSRFVLLNLTFPSQETIIRIFGTMLCQKL----E 2596
            .......:.|...:|.|.|..|. .||:.|.|..|.:|.::||..|:|..::.::|.|..    :
  Fly  2585 NKLTLKDIHNCQYVACMNPTSGS-FTINPRLQRHFCVLAVSFPGPESITVMYSSILAQHFANAEQ 2648

  Fly  2597 SYPNEVREMWLPITLCTINLYVSMISKMLPTPNKSHYLFNLRDISKVFQGLLRSEKELQNKKNFF 2661
            .:...|..|...|...||.|:...:...|||..||||:|||||||.||||||.|..|........
  Fly  2649 KFTPIVTRMTPNIVAATIALHNKCLQVFLPTAIKSHYIFNLRDISNVFQGLLFSSTECLTGSTDL 2713

  Fly  2662 LRLWVHECFRVFSDRLVDDSDQFWFVNTINDILGKHFEVTFHSLC---PSKVPPFFGDFAHP--- 2720
            :|||.||..||:||:|.||.|...|....:||:.|.||....|:.   |:....|.|....|
  Fly  2714 IRLWQHETQRVYSDKLTDDKDIDSFTKMQHDIVKKSFEEIDESVIFDKPNIYCHFAGGIGDPKYM 2778

  Fly  2721 --QGFYEDLQVDFLRTFMKNQLEEYNNFPGMTRMNLVFFREAIEHIVRILRVISQPRGHILNMGI 2783
              :|:.|      |...::..:..||:.  :..||||.|.:|:.|:.||.|::..|||..|.:|:
  Fly  2779 PIKGWPE------LHKLLQEAMSSYNDL--VAAMNLVLFEDAMMHVCRINRILESPRGSALLVGV 2835

  Fly  2784 GGSGRQVLTKLAAFILEMAVFQIEVTKKYKTGDFREDLKNLYKVTGIKQRLTIFIFSSDQIAEVS 2848
            ||||:|.|.:|||||..:.|.||::.|.|...|.:.:...||...|:|....:|:.:..||....
  Fly  2836 GGSGKQSLARLAAFISSLEVVQIQLKKGYGVNDLKNEFSGLYLKAGLKNVGIMFLMTDAQIPSED 2900

  Fly  2849 FLEITNNMLSTGEI-NLFKSDEFDELKPELERPAKKNGVLLTTEALYSYFILNVRDFLHVALCFS 2912
            ||.:.|:||:|||| :||..||.:.:...:....|..|::.|.|..:.:||..||..|.:.||||
  Fly  2901 FLVLINDMLATGEIPDLFPDDEIENIIAGVRNEVKGAGLVDTRENCWKFFIDRVRKQLKIVLCFS 2965

  Fly  2913 PIGENFRSYIRQYPALLSSTTPNWFRFWPQEALLEVASHFLIGFPLNVVVSGKEDEKHRESLVIS 2977
            |:|...|...|::||::::|:.|||..||||||:.||.:||   ..|.|:    .|.||:|
  Fly  2966 PVGSTLRVRSRKFPAIINATSINWFHEWPQEALISVAMNFL---AQNKVL----PENHRDS---- 3019

  Fly  2978 TEAILQRDIAYVFSVIHSSVAKMSENMYAEVKRYNYVTSPNYLQLVSGFKKLLEKKRLEVSTASN 3042
                    :|...:.:|:||...|:......:||||.|..:||:.::.:.|||..|..::.:...
  Fly  3020 --------VAKFMAYVHTSVNTTSKVYLQNERRYNYTTPKSYLEQINLYIKLLNHKNEDLQSKIE 3076

  Fly  3043 RLRNGLSKISET-------QEKVSLMSEELKASSEQ----VKILARECEDFISMIEIQKSEATEQ 3096
            ||.|||.|:..|       :.|:::...|||..:|.    ::|:..|.|    .::.:|:.|.|:
  Fly  3077 RLENGLEKLRSTALQVADLKVKLAVQEIELKEKNEAADALIEIVGIETE----KVQTEKAVADEE 3137

  Fly  3097 KEKVDAEAVLIRRDEIICLELAATARADLEVVMPMIDAAVKALDALNKKDISEVKSYGRPPMKIE 3161
            :.||...|..:.:.:..|.|       ||....|.:.||..||:.|||.:::|:||:|.||..:.
  Fly  3138 EMKVALIADEVSKKQRDCEE-------DLLKAEPALMAAQDALNTLNKANLTELKSFGSPPGAVT 3195

  Fly  3162 KVMEAVLILL---GKEP---TWENAKKVLSE-STFLNDLKNFDRDHISDKTLKRIAIYTKNPELE 3219
            .|..||::||   ||.|   :|:.||..::: .|||:.|.|:|:::|..:..|.|..|.|:||.|
  Fly  3196 NVTAAVMVLLSQGGKVPKDRSWKAAKIAMAKVDTFLDSLINYDKENIHPEITKAIQPYLKDPEFE 3260

  Fly  3220 PDKVAVVSLACKSLMQWIMAIENYGKVYRIVAPKQEKLDSAMKSLEEKQAALAAAKKKLEELQVV 3284
            |:.|...|.|...|..|::.|..:.:||..|.||::.|.:|...|...|..||..|:|:..|:..
  Fly  3261 PEFVRSKSGAAAGLCAWVINIIKFYEVYCDVEPKRKALAAANAELAAAQDKLAGIKRKVMSLEEQ 3325

  Fly  3285 IEELYRQLEEKTNLLNELRAKEERLRKQLERAII--LVESLSGERERWIETVNQLDLSFEKLPGD 3347
            :.:|....|:.|  .::||.::|....|...|:.  ||..|:.|..||.|.||........||||
  Fly  3326 LGKLTADFEKAT--ADKLRCQQEADATQATIALANRLVGGLASENVRWAEAVNNFVKQGITLPGD 3388

  Fly  3348 CLLSVAFMSYLGAFDTKYREELLVK-WSLLIK--DLLIPATLELKVTYFLVDAVSIREWNIQGLP 3409
            .||..||:||:|.|...:|.:||:| |:..:|  |..||.|..|.....|.|..:|..|..:|||
  Fly  3389 ILLITAFISYVGCFTKGFRIDLLLKMWTPFLKSIDPPIPTTENLDPLSLLTDDTTIAIWTNEGLP 3453

  Fly  3410 ADDLSTENGVIVTQGSRWPLIIDPQMQANNWIKNMEERNQLMTLDFGMADYLRQLERALKEGLPV 3474
            :|.:|.||..|::...||||:||||:|...||| .:....|..:..|...||..:|:::..|..|
  Fly  3454 SDRMSIENATILSNSDRWPLMIDPQLQGVKWIK-QKYGEDLKVIRLGQRSYLDIIEKSINAGCNV 3517

  Fly  3475 LLQNVGEYLDQAINPILRQSFTIQSGERLLKFNDKYISYNNSFRFYITTKISNPHYPPEISSKTT 3539
            |::|:.|.||..::.:|.::. |:.| :.:|..||.|.||::||..:.||::||||.||:.::||
  Fly  3518 LIENIDENLDPVLDSLLGRNL-IKKG-KAIKIGDKEIEYNSNFRLILHTKLANPHYKPEMQAQTT 3580

  Fly  3540 IVNFALKQDGLEAQLLGIIVRKEKPALEEQKDELVMTIARNKRTLIDLDNEILRLLNESRGSLLD 3604
            ::||.:.:||||.|||..:|:.|:|.|||.|.:|.......|..|..|::::|..|:.:..::|.
  Fly  3581 LINFTVTRDGLEDQLLAEVVKAERPDLEELKADLTKQQNDFKIMLKKLEDDLLSRLSSAGENILG 3645

  Fly  3605 DDELFSTLQKSRQTSVLVKESLSIAEVTEVEIDAARQEYKPASERASILFFVLMDMSKIDPMYVF 3669
            |..|...|:.::.|:..:::.::.|::|..|||.||:.|:||:.|||:|:|:|.:::.|:|:|.|
  Fly  3646 DTALVENLETTKSTASEIEQKVAEAKITSKEIDKAREYYRPAAARASLLYFILNELNTINPIYQF 3710

  Fly  3670 SLAAYILLFTQSIERSPRNQLVHERIQNINEYHSYAVYRNTCRGLFERHKLLFSIHMTAKILSNA 3734
            ||.|:.::|.::|.::.....:..|:.|:.:..:|:|::.|.|||||..||:|:..||.:||...
  Fly  3711 SLKAFSVVFQKAIAKAEPGDTLDLRVSNLIDCITYSVFQYTSRGLFECDKLIFASQMTFQILLMN 3775

  Fly  3735 GKLLEEEYDFILKGGIVLDKLGQAPNPAPWWISEQNWDNITELDKVSGFHGIIDSFEQHYKAWNG 3799
            .::...|.||:|:..|    .....:|.. :::.|:|..|..|.....|..:....|...|.|..
  Fly  3776 EEVTSAELDFLLRFPI----KPHVTSPVD-FLTNQSWGGICSLASKDEFRNLDRDIETSSKRWKK 3835

  Fly  3800 WYATTFPEQEDLVGEWNDKLTDFQKICVLRSLRPDRISFCLTQFIITKLGPRYVDPPVLDLKATF 3864
            ...:..||:|....||.:| |..|::|::|:|||||:::.|..||..|||.:||:...::...::
  Fly  3836 LVESELPEKEKFPQEWKNK-TALQRLCMIRALRPDRMTYALADFIEEKLGSKYVESRAMEFAKSY 3899

  Fly  3865 DESISQTPLIFVLSPGVDPAQSLISLSESVKMAQ---RMYSLSLGQGQAPIATKLIMDGIKDGNW 3926
            :|:...||:.|:|||||:|.:.:.:|.:.:..:.   ..:::||||||..||...:....|.|:|
  Fly  3900 EEASPSTPIFFILSPGVNPLKDVEALGKQMGFSMDLGNFHNVSLGQGQEAIAEAAMDTAAKHGHW 3964

  Fly  3927 VFLANCHLSLSWMPTLDKMIATMQSMKLHKKFRLWLSSSPHPD-----FPISILQTSIKMTTEPP 3986
            |.|.|.||...|:|.|:|.: ...:...|..:|::||:.|...     .|..||::|||:|.|||
  Fly  3965 VVLQNIHLVRKWLPVLEKKL-EYYAEDSHPDYRMFLSAEPASTPSAHIIPQGILESSIKITNEPP 4028

  Fly  3987 RGIKSNMKRLYNNINEANMENCSEPSKYKKLLFALCFFHTVLLERKKFLELGWNVIYSFNDSDFE 4051
            .|:.:|:.:..:|..:..:|...:.:::|.:||:||:||.|:.||:||...|||.||.||..|..
  Fly  4029 TGMLANLHKALDNFTQETLEMSGKEAEFKAILFSLCYFHAVVAERRKFGPQGWNKIYPFNVGDLN 4093

  Fly  4052 VSEILLLLYLNEYEDTPWGALKYLIAGVNYGGHITDDWDRRLLITYINQFFCDQALQTRKFRLST 4116
            :|..:|..||......||..|:||...:.|||||||||||||.|||:.::.....:....|   .
  Fly  4094 ISVSVLYNYLEANAKVPWEDLRYLFGEIMYGGHITDDWDRRLCITYLEEYMQPDLVDGELF---L 4155

  Fly  4117 LPNYFIPDDGDVQSYLDQIQMFPNFDKPDAFGQHSNADIASLIGETRMLFEALLSMQVQTNST-- 4179
            .|::..|.:.|.|.|...:......:.|..:|.|.||:|..|......:|..:..||.:....
  Fly  4156 APSFPAPPNTDYQGYHTYVDEMMPAESPYLYGLHPNAEIGFLTTRAENIFRTVFEMQPRDAGAGG 4220

  Fly  4180 SSNENGETKVFDLAKEILMNTPDEINYEQTAKIIGINRTPLEVVLLQEIERYNKLLVDMSTQLRD 4244
            .:....|.||..:..||:...|:|.|..:....:. .|||..:|..||.||.|.|..:|...|::
  Fly  4221 GATVTREDKVKQIVDEIIEKLPEEFNMVEIMNKVE-ERTPYVIVAFQECERMNFLTSEMKRSLKE 4284

  Fly  4245 LRRGIQGLVVMSSDLEDIYLAVSEGRVPLQWL-KAYNSLKPLAAWARDLIHRVGHFNSWAKTLRP 4308
            |..|::|.:.::||:|.:..::...:||..|. :||.||..|..|..||..|:....:|:.....
  Fly  4285 LDLGLKGELTITSDMEVLENSLFLDQVPPIWTQRAYPSLLGLNNWFIDLCLRLRELETWSTDFVL 4349

  Fly  4309 PILFWLAAYTFPTGFVTAVLQTSARATKTPIDELSWDFYVF---VEEDTAAARIIREGGGVYIRS 4370
            |...|||.:..|...:||::|::||....|:|::.....|.   .||.|.|.|     .|..:..
  Fly  4350 PSCVWLAGFFNPQSLLTAIMQSTARRNDLPLDKMCLQCDVTKKQKEEFTTAPR-----DGCCVHG 4409

  Fly  4371 LFLEGGGWLRKNQCLQDPLPMELICPLPVIHFKPVENLKKRCRGVYQCPAYYYPVRS-GSFVIAV 4434
            :|:||..|..:...:.:....||...:|||:.:.:...|:..|.:|:||.|....|. .::|..:
  Fly  4410 IFMEGARWDIQQGIIMESRLKELYPSMPVINIRAITQDKQDLRNMYECPVYKTRTRGPTTYVSNL 4474

  Fly  4435 DLKSGNEKADYWIKRGTALLL 4455
            :||: .:|...||..|.||||
  Fly  4475 NLKT-KDKPGKWILAGVALLL 4494

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kl-2	NP_001015505.5	DHC_N1	178..749	CDD:285571	115/609 (19%)
		DHC_N2	1244..1646	CDD:285579	128/416 (31%)
		P-loop_NTPase	1785..2015	CDD:304359	141/229 (62%)
		P-loop_NTPase	2099..2242	CDD:304359	62/149 (42%)
		P-loop_NTPase	2401..2668	CDD:304359	94/270 (35%)
		P-loop_NTPase	2752..3030	CDD:304359	104/278 (37%)
		MT	3043..3373	CDD:289543	118/350 (34%)
		AAA_9	3402..3618	CDD:289547	80/215 (37%)
		Dynein_heavy	3760..4447	CDD:281078	221/701 (32%)
Dhc93AB	NP_001262793.1	DHC_N1	204..782	CDD:285571	115/608 (19%)
		DHC_N2	1295..1708	CDD:285579	132/433 (30%)
		P-loop_NTPase	1841..2071	CDD:304359	141/229 (62%)
		P-loop_NTPase	2155..2290	CDD:304359	61/148 (41%)
		P-loop_NTPase	2448..2720	CDD:304359	94/273 (34%)
		P-loop_NTPase	2797..3064	CDD:304359	106/287 (37%)
		MT	3076..3419	CDD:289543	119/355 (34%)
		AAA_9	3447..3659	CDD:289547	80/214 (37%)
		Dynein_heavy	3799..4486	CDD:281078	220/699 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450555
Domainoid	1	1.000	84	1.000	Domainoid score	I5259
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1492at2759
OrthoFinder	1	1.000	-	-		FOG0000396
OrthoInspector	1	1.000	-	-		otm47047
orthoMCL	1	0.900	-	-		OOG6_100025
Panther	1	1.100	-	-	P	PTHR10676
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.850