Protein Alignment kl-2 and sac

DIOPT Version :10

• Sequence 1: NP_001015505.5
• Gene: kl-2 / 3355181
• FlyBaseID: FBgn0001313
• Length: 4459
• Species: Drosophila melanogaster
• Sequence 2: NP_649475.3
• Gene: sac / 40568
• FlyBaseID: FBgn0037254
• Length: 1079
• Species: Drosophila melanogaster
• Alignment Length: 1070
• Identity: 188/1070 - (17%)
• Similarity: 367/1070 - (34%)
• Gaps: 364/1070 - (34%)

  Fly   293 PTFVSQLI----------PRTIHLIRFIWLNSEQYNRRDLITGIFR-NLSNQIIRFCTEKVNVEK 346
            ||.:.::|          |:.:.:.|    ...||.:.:|:..:.: .|::.:::...|:.||..
  Fly    97 PTILPKVIQTRYVPKRHLPKDVEVDR----RRRQYQKINLVNELAKAGLTDDVLQPTEEQYNVMS 157

  Fly   347 ILS----------GSSRFGIKICNMCIDCCLTYKGIYDIMSKTHAKIN---IRIGWSLDNAMIFN 398
            ..:          ..|.|.|.......:..:.....|.:.:|.:...|   :...|.: .|:..:
  Fly   158 EFAFPHKFPLSYFDDSNFDINSPAAWFELGVVGDAHYPLPAKAYLPYNQSLLNCQWGM-AAVTAH 221

  Fly   399 HVDAFMERLNDVIDICESMMVFGRLDESESIPKPQFGGTSGTEFE-------ATADNVENEFLVT 456
            |.|:.:..|..:.|.|           :.::||.||...:....:       |..:..:.|.|:.
  Fly   222 HEDSDLWTLLSLEDGC-----------TYTVPKLQFMFMAEDPHKYIKRLQAAVHERHKGEQLML 275

  Fly   457 LTALCTDSKEIILNVHKNEWYEEVIKYR-RTVQSM-------EETVQRLMSN---VFQHICNVEE 510
            :        |:|::...:|..|..:.|. :.::|:       |:..:||.|.   ||:.:..:.|
  Fly   276 M--------ELIVDCVLHEDIESTVFYSFKPIESVLQAAKVSEQCKRRLRSEVNLVFERLMALYE 332

  Fly   511 ALESLNVMI---FYSYRSTIRKTFLRQVSSAWVFFSNEIDSSVHMLMDRSKMHESWVPYYASRAL 572
             ||...:.:   |..:|:...|.||.:..:..|.....::.....:..:.|.::     |...:|
  Fly   333 -LEQFILKMPKEFPQFRNINLKEFLPRSFAVDVSGKERLELQALGITMQEKRYD-----YLKASL 391

  Fly   573 GYRV--------------HLDRL-VWLCN---RLNSSDWLPNVSEA-----SVVLK-----KFES 609
            .|.|              :::.| :::|:   .|...|:| ...||     :..||     :..:
  Fly   392 FYCVGGIEAMAGVAIECQYIETLSIFICSFSKPLALVDFL-QAQEAHSDNVATFLKVYWPQQLTT 455

  Fly   610 VRREFDKEVKKSFDEWQKNCCSLLLNQKLDRYLLIRSKKKKGLIECNIDRTILT----ICEQAQH 670
            |.....:.:.|.:.:...|..::.|..|:.|::|....:.:..:|..::.:::.    :|:....
  Fly   456 VITVVLRALGKGWLDISLNTWTVYLMCKISRFILQVKFRMQESMEVLLETSLMNFSHFVCDPCLQ 520

  Fly   671 FERL------------------------GLGV----------------PGMV---RKIYEKHETL 692
            |..|                        .||:                ||:|   :|..||...:
  Fly   521 FLELKSNYKWTNNYIDTEFPFQKPVFAMTLGISEDRKVFYSTDPDEFQPGLVEIFKKCLEKSSGV 585

  Fly   693 RFVYNSVVQVCLNYNHILSALSEQERKLFRALIQACDRKIAPGVFKLTYGGELSDAYIADCAKHT 757
            |.:..||:...                           |.||.::.||.  ||    |.|.....
  Fly   586 RCIDGSVMSFL---------------------------KFAPNLYILTV--EL----IEDRFLRE 617

  Fly   758 NKLQETMDIYKRAI---QNIARFCEKICDTPMLKFNF-----------SGAVTISIFENHLSSYL 808
            |:|.:  :.|.:|:   :..||..|:..|..:|..|.           |..|...|.||
  Fly   618 NELLK--NCYAKAVLPLRAYARLYERFIDFYLLNVNTYMQAYAQAHKPSSEVKRDILEN------ 674

  Fly   809 RRVSNILRGFYSTITDLIFAVFKEFQAVIEDMPIEWYGFVNVFDDMLATAFLTSSKNSLNMLTNA 873
            :|:...||                     |.:|                ||:|.....:|:.|
  Fly   675 KRLKEELR---------------------EILP----------------AFITIGPFYINVDT-- 700

  Fly   874 LHRDPDMAAAPILVMESDVRERCIVLTPDIDVIANLLSGYIDRIH--------NILEQFPRIGIK 930
                         :.:..:::|       |:|:..:...|:||::        ..||.|.||. :
  Fly   701 -------------MKQFMIKKR-------IEVVRRIFEYYVDRMYETNEVLLDRCLEMFRRIA-E 744

  Fly   931 MKLPKEHQYESFSKAFLEDSEST--QLICNIEAEIN---HEREEIDGYITFWNSHR--MLW---- 984
            ..:..||.||      :.|...|  .|:..::|:|.   .|.:.:|.:....:.|:  |.|
  Fly   745 RPISIEHLYE------IRDFAQTVPDLVDELKADIQVMWLEYDLLDSFFYNLSDHQFAMKWNVYA 803

  Fly   985 ---------------ETTELEFTKRVKATQMTADIFEASIEYYSAMADDISYVDAITHVYFILMN 1034
                           :..::|...|:.|::..|  ||..:|   ::.|::       ..|.:..|
  Fly   804 WPHQIMVRLSTLKDEQKVDIEDFLRLHASECQA--FEERLE---SLNDEV-------QAYSLAFN 856

  Fly  1035 QNYIKSSILDCIEKWQALNIKILLSHSFSLIRAIYRYMRKNERKMMMVPRTLKESLLAKQFFERI 1099
            .|..:.:.:|..:.|                 |:.:.:.|..:.:.......:...|:.:|.|.|
  Fly   857 TNRAQETSVDIKKTW-----------------ALIKELEKVSQTLQFRQELFELEPLSVEFLESI 904

  Fly  1100 INEVPLKQAGFPPTLEL------FAILDKYQVEIPEEIRVKVIGLEAAWHHYLKRLGEADEMLDN 1158
            |       |.|.|...|      |..|:...:..|    :..:.||..|::.::...|.:|.:
  Fly   905 I-------ASFTPYKNLWYGCANFLKLEDATLGNP----IAQLDLEDVWNNLMRLRDELNESM-- 956

  Fly  1159 NREEFKKILVQQAEKFKIILKEF---LDDF 1185
                  ||..::.| ...:.|.|   :|||
  Fly   957 ------KIFHEKVE-IMDVAKTFIAKIDDF 979

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kl-2	NP_001015505.5	DHC_N1	180..749	CDD:462457	96/575 (17%)
		DHC_N2	1238..1646	CDD:462462
		DYN1	<1478..4135	CDD:227570
		AAA_6	1785..2111	CDD:463697
		Dynein_C	4161..4455	CDD:465677
sac	NP_649475.3	DHC_N2	901..>1042	CDD:462462	23/99 (23%)