DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment kl-2 and Dnah3

DIOPT Version :9

Sequence 1:	NP_001015505.5	Gene:	kl-2 / 3355181	FlyBaseID:	FBgn0001313	Length:	4459	Species:	Drosophila melanogaster
Sequence 2:	NP_001357735.1	Gene:	Dnah3 / 381917	MGIID:	2683040	Length:	4072	Species:	Mus musculus

Alignment Length:	4178	Identity:	1382/4178 - (33%)
Similarity:	2166/4178 - (51%)	Gaps:	556/4178 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   583 WLCNRLNSSDWLPNVSEASVVLKKFESVRREFDKEVKKSFDEWQKNCCSLLLNQKLDRYLLIRSK 647
            ::| :.:||..:.|.:::||...:...:..|...:|              :|.|:::    |.||
Mouse   150 FVC-KFSSSLSIKNTTDSSVTHPESRPMSPEQQMDV--------------MLQQEME----IESK 195

  Fly   648 KKKGLIECNIDRTILTICEQAQHFERLGLGVPGMVRK---IYEKHETLRFVYNSV---------- 699
            ::|. .|.:::|          ::..|..|    :||   ..|..|.:..:|..:
Mouse   196 EQKP-SELDLER----------YYYYLTNG----IRKDMIAPENEEVMMRIYKLIPKTLLTTPAL 245

  Fly   700 --VQVCLN---------------YNHILSALSEQERKLFRALIQACDRKI--AP----GVFKLTY 741
              :||.|.               .::||....|::|...:::.:....::  ||    .:::.|
Mouse   246 EPLQVSLRSEKESDYYYSLMKSIVDYILMDPMEKKRLFIKSIPRLFPHRVIRAPVPWHNIYQST- 309

  Fly   742 GGELSDAYIADCAKHTNKLQETMDIYKRAIQNIARFCEKICD-----TPMLKFNFSGAVTISIFE 801
             .:.::.::........||:|   ::....||: ||. :..|     .|:|...:...|
Mouse   310 -KKWNEEHLHTVNPMMYKLKE---LWFAEFQNL-RFV-RTADLLAGKLPLLPHEYKEVV------ 362

  Fly   802 NHLSSYLRRVSNILRGFYSTITDLIFAVFKEFQAVIEDMPIEWYGFV--NVFDDMLATAFLTSSK 864
               ..:.|...:||...:......:|...||          .|..|.  |.:|         ||:
Mouse   363 ---QKHCREARHILLTKWIPTCAQLFVTQKE----------HWVHFAPKNDYD---------SSR 405

  Fly   865 N----------------------SLNMLTN--ALHRD----------PDMAAAPILVMESDVRER 895
            |                      ||..|.:  .:|:|          .|.....:::::.:||:.
Mouse   406 NIEEYFASVASFMSLQLRDLVIKSLRDLVSFFMIHKDGNDFKEPYQEMDFFIPQLIMIKLEVRDP 470

  Fly   896 CIVLTPDID------------VIANLLSGYIDRIHNILEQFPRI-GIKMKL----PKEHQYESFS 943
            .||..|..|            :|.|  |..|.::.:||  ||.: |..|.|    |:|.....|.
Mouse   471 IIVFNPTFDDCWQLIKNSFLEIIKN--SDGIPKVESIL--FPDLKGYNMILGTVNPEESLVSDFL 531

  Fly   944 KAFLEDSESTQ---------------LICNIE----AEINHEREEIDGYITFWNS-HRMLWETTE 988
            ...||..:..|               |:.|:.    :|...|:.||:.::|..|| .:...|...
Mouse   532 DQTLEVFKKNQVGPYKYLNVYKKYDDLLDNMAEKGISEFLKEKHEIEDFVTSINSIKKRKNEIAS 596

  Fly   989 LEFT------------------KRVKATQMTADIFEASI---------EYYSAMADDISYVDAIT 1026
            :..|                  :|.:..:....:::..:         ..||.:||.:|.:.|.|
Mouse   597 MHITVPLAMFCLDAVFLNYDLCERAQNLKDNLILYQVDVNRETNTSICNQYSTIADKVSEIPANT 661

  Fly  1027 HVYFILMNQNYIKSS-----------ILDCIEKWQAL-------NIKILLSHSFSL----IRAIY 1069
            .....|:  .|:|.|           :.|..|:.:.|       |..|.|:.:..|    |..::
Mouse   662 AELVALI--EYLKKSSDVTVFKLRRQLRDASERLEFLMDYADLPNEDIKLNSNLFLWPDQIEDVF 724

  Fly  1070 RYMRKNERKMMMVPRTLKESLLAKQFFERIINEVPLKQAGFPPTLELFAILDKYQVEIPEEIRVK 1134
                ::.|.::|..|...|..|.|:     .:|...:..|:...||:|.   |.:|...||::..
Mouse   725 ----ESSRNLLMSKRDQAEMDLIKR-----CSEFESRLEGYSKELEMFR---KREVMTTEEMKNN 777

  Fly  1135 VIGLEAAWHHYLKRLGEADEMLDNNREEFKKILVQQAEKFKIILKEFLDDFFLKLPTSANINPRI 1199
            |           ::|.:..:.||....|           |::|.||
Mouse   778 V-----------EKLHDLSKNLDLALTE-----------FELINKE------------------- 801

  Fly  1200 ALKFLRIIALKIEDCFTFEESLMRDLAVFNVNQPESIDLRKLDFEVRIVKNIWELIFEWQTNWEG 1264
                              ||.|.::.:.|.:.|  ::.:.|:.:|     .:|...:|:.|..|.
Mouse   802 ------------------EELLEKEKSSFPLLQ--TLMINKIPYE-----QLWVTAYEFSTKSEE 841

  Fly  1265 WKKGYFWKMNINEMEDTALNLYKEFTTLNKKFYD--RHWEMLEATTKNVDSFRRTLPLITALKNP 1327
            |..|..:.||..::.:...|:::....|.|...|  ....:.|.....::.|::.:|::....||
Mouse   842 WMNGPLYLMNAEQIAEEIGNMWRTTYKLTKTLIDVPAPKRLAENVKLKIEKFKQHIPILNIACNP 906

  Fly  1328 CMRERHWNRVRDVIHVNFDENSKNFTLELIINLDFQAFSEDIQDISNPATMELQIENSIKNIATI 1392
            .|::|||.::.|::.... :.::...|..::...|..|.:.::.|...|:.|..:|.:::.:...
Mouse   907 GMKDRHWQQISDIVGYEI-KPTETTCLANMLEYGFGKFVDKLEPIGAAASKEYSLEKNLEKMKAD 970

  Fly  1393 WKKQSFEMAFYHDGIYRIKNVEDCFQL-LEEHMVQISAMKATRFVEPFITIVDYWEKTLSYISET 1456
            |....|....|.|....|....|..|| |::|:::...|..:.|::|.......||:.|..:.|.
Mouse   971 WVNMCFSFVKYRDTDTSILCAVDDIQLILDDHVIKTQTMCGSVFIKPIEAECRKWEEKLVRVQEN 1035

  Fly  1457 LEKGLTVQRQWLYLENIFQGDDIRKQLPEEAKRFATITEEFRTISSKMFQAKTAVKATNLRPPPF 1521
            |:..|..|..|||||.||..:||..|:|||.|:|.|:...::::   |.||....:.......|.
Mouse  1036 LDAWLKCQVTWLYLEPIFSSEDIIAQMPEEGKKFTTVDTYWKSL---MAQAVNDTRVMVAADQPR 1097

  Fly  1522 LLNRFSRMDERLELIQRALEIYLEAKRQLFPRFYFISNDDLLEILGNSKRPDLVQTHLKKLFDNL 1586
            :..:....:..||.|||.|..|||.||..||||:|:|||:|||||..:|.|..||.||||.|:.:
Mouse  1098 MTEKLQEANVLLEDIQRGLNDYLEKKRLFFPRFFFLSNDELLEILSETKDPLRVQPHLKKCFEGI 1162

  Fly  1587 YKLELKRVGKTLSRWQASGMHSDDGEYVEFMMVIY---IDGPSERWLKQVEEYMLVVMKEMLKLT 1648
            .|||.      ....:..||.|.:.|.|.|:..||   ..|..|:||:|||:.||..|:::::
Mouse  1163 AKLEF------TDNLEIKGMISSEKETVPFIQTIYPVKAKGMVEKWLQQVEQVMLASMRQVIE-- 1219

  Fly  1649 RGSLKKLVGNREKWISLWPGQMVLTTAQIQWTTECTRSLIHCSMVDQKKPLRKLKKKQIKVLSKL 1713
            .|....:...|..|:..||||:|:..:.|.||.|.:.:|:..::.|       ..||....::::
Mouse  1220 NGIEAYVQVPRNAWVLEWPGQVVICVSSIFWTREVSEALVEDTLTD-------FLKKSNDQIAQI 1277

  Fly  1714 SEMSRKDLTKTMRLKVNTLITLEIHGRDVIERMYKSNCKDTGHFEWFSQLRFYWHRESELCVIRQ 1778
            .|:.|..|:...||.:..|..:::|.|||:.::...:......|:|.||||:||..::  ..::.
Mouse  1278 VELVRGKLSSGARLTLGALTVIDVHARDVVAKLRHDHINSLNDFQWISQLRYYWTEKN--VHVQM 1340

  Fly  1779 TNTEHWYGYEYTGNSGRLVITPLTDRCYITLTTALHLHRGGSPKGPAGTGKTETVKDLGKALGIW 1843
            ..||..|||||.|||.||||||||||||.||..||.|:.||:|:||||||||||.|||.|||...
Mouse  1341 ITTEALYGYEYLGNSPRLVITPLTDRCYRTLMGALKLNLGGAPEGPAGTGKTETTKDLAKALAKQ 1405

  Fly  1844 VIVTNCSEGLDYKSIGKNFSGLAQSGCWGCFDEFNRINIEVLSVVAQQIMSIMAALSTKALELMF 1908
            .:|.|||:|||||::||.|.||||:|.|.||||||||.:||||||||||:||..|:..|....:|
Mouse  1406 CVVFNCSDGLDYKAMGKFFKGLAQAGAWACFDEFNRIEVEVLSVVAQQILSIQQAIIRKLKRFIF 1470

  Fly  1909 EGQMIKLKHTVGLFITMNPGYAGRTELPDNLKSMFRPISMMVPDNIIIAENLLFSDGFTNTRNLA 1973
            ||..:.|..|..:|||||||||||.|||||||::||.::|||||..:|.|..|:|.||.::|:||
Mouse  1471 EGTELSLNPTCAVFITMNPGYAGRAELPDNLKALFRTVAMMVPDYALIGEISLYSMGFLDSRSLA 1535

  Fly  1974 RKVYTLYELAKQQLSKQYHYDFGLRSMVALLRYAGRKRRQLPNTTEEEIVYLAMKDMNVARLTAN 2038
            :|:...|.|..:|||.|:|||:|:|::.::|..||..:.:.|...|..::..|:.|:|:|:..|.
Mouse  1536 QKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPEENESVLLLRALLDVNLAKFLAQ 1600

  Fly  2039 DLPLFNGIMSDIFPGVSLPTIDYSEFNIAIYEEFREAGLQPITIAVKKVIELFETKNSRHSVMII 2103
            |:|||.||:||:||||.||..||..|..|:....|:..|||:...:.|:|:::|....||..||:
Mouse  1601 DVPLFQGIISDLFPGVVLPKPDYEVFLEALNNNIRKMKLQPVPWFIGKIIQIYEMMLVRHGYMIV 1665

  Fly  2104 GDTGTAKSVTWRTLQNCFYRMNSQRFSGWEAVTVYPVNPKALNLAELYGEYNLSTGEWLDGVLSS 2168
            ||....|:..::.|......:::.......||....:||||:.:.:|||.::..:.||.||||::
Mouse  1666 GDPMGGKTSAYKVLAAALGDLHAANQMEEFAVEFKIINPKAITMGQLYGCFDAVSHEWTDGVLAN 1730

  Fly  2169 IMRIICGDEEPTQKWLLFDGPVDAVWIENMNSVMDDNKLLTLVNSERITMPVQVSLLFEVGDLAV 2233
            ..|.........:||::||||||||||||||:|:||||.|.|::.|.|.|..::||:||..||..
Mouse  1731 AFREQASSITDDRKWIIFDGPVDAVWIENMNTVLDDNKKLCLMSGEIIQMSSKMSLIFEPADLEQ 1795

  Fly  2234 ASPATVSRCGMVYNDYNDWGWKPFVNSW---LQRLRIKEFADFLRIHFDYMVPKILDFKRMRCKE 2295
            |||||||||||:|.:.:..||||..:|:   |.|...||..:.:...|.::|...|||.|:.||.
Mouse  1796 ASPATVSRCGMIYMEAHQLGWKPLKDSYMDTLPRCLTKEHTELVEDMFTWLVQPCLDFSRLHCKF 1860

  Fly  2296 PVRTNELNGVVSLCKLLEIFGTKVNGINPINLELLEEMTR----LW----FMFCLVWSICSSVDE 2352
            .|:|:.::...|:.:|......::..|....:|:.|.::.    ||    |:|.|||::..:::.
Mouse  1861 VVQTSPIHLAFSMMRLYSSLLDEIRDIQEEEMEIYEGLSSQQIFLWLQGLFLFSLVWTLAGTINA 1925

  Fly  2353 DSRQRLDSFIREL------------------ESCFPIKDTVFDY---------------FVDPNE 2384
            :||::.|.|.|.|                  .:.||.:.:::|:               ::...|
Mouse  1926 ESRKKFDVFFRNLIMGMDDRNPRPKSVKLTKNNIFPERGSIYDFYFLKQGGGHWNAWTEYITKEE 1990

  Fly  2385 RTFLPWDSKLLSSWKCDFESPFYKIIVPTGDTVRYEYVVSKLLAEEYPVMLVGNVGTGKTSTAIS 2449
            .| :|.::|:..            :|:||.:|.|..:.:...|..|.|::.||..||||::....
Mouse  1991 ET-IPANAKVSD------------LIIPTMETARQSFFLKTYLDHEIPILFVGPTGTGKSAITND 2042

  Fly  2450 VMEACDKNKFCILAVNMSAQTTAAGLQESIENRTEKRTKTQFVPIGGKRMICFMDDFNMPAKDIY 2514
            .:....||.:....:|.||:|:|...|:.|.::.::|.|..|.|..||:.:.|:||.|||||::|
Mouse  2043 FLLHLPKNVYQPNFINFSARTSANQTQDIIMSKLDRRRKGLFGPPIGKKAVVFVDDLNMPAKEVY 2107

  Fly  2515 GSQPPLELIRQWIDYKYWFNRKTQQKIYVQNTLLMAAMGPPGGGRQTISSRTQSRFVLLNLTFPS 2579
            |:|||:||:|||||:.|||::|...::.:.:.||:.|||||||||..|:.|......::::....
Mouse  2108 GAQPPIELLRQWIDHGYWFDKKDTNRLDIVDVLLVTAMGPPGGGRNDITGRFTRHLNIISINAFE 2172

  Fly  2580 QETIIRIF-------------------GTMLCQKLESYPNEVREMWLPITLCTINLYVSMISKML 2625
            .|.:.:||                   |.||.|                  .|..:|.:.:...|
Mouse  2173 DEILTKIFSSIADWHFGKGFDVMFLRYGKMLVQ------------------ATQTIYRAAVENFL 2219

  Fly  2626 PTPNKSHYLFNLRDISKVFQG-LLRSEKELQNKKNFFLRLWVHECFRVFSDRLVDDSDQFWFVNT 2689
            |||:||||:|||||.|:|.|| ||.....||:.:. |:|||:||.:|||.|||:|:.|:..|.|.
Mouse  2220 PTPSKSHYVFNLRDFSRVIQGVLLCPHTHLQDLEK-FIRLWIHEVYRVFYDRLIDNDDRQTFFNL 2283

  Fly  2690 INDILGKHFEVTFHS----LCPS-KVPP------FFGDFAHP---QGFYEDLQVDF--LRTFMKN 2738
            :.:.....|:.|...    |.|: |:..      ||||:..|   |..|::: :|.  |...|:.
Mouse  2284 VKETTSNCFKQTMEKVLIHLSPTGKITDDNIRSLFFGDYLKPESDQKIYDEI-IDLRGLTVVMEY 2347

  Fly  2739 QLEEYNNFPGMTRMNLVFFREAIEHIVRILRVISQPRGHILNMGIGGSGRQVLTKLAAFILEMAV 2803
            .|:|:|:. ....|:||.|:.|||||.||.||:.|.:||:|.:||||||||..|||:.|:....:
Mouse  2348 YLDEFNSV-SKAPMSLVMFKFAIEHISRICRVLKQKKGHLLLVGIGGSGRQSATKLSTFMNSYEL 2411

  Fly  2804 FQIEVTKKYKTGDFREDLKNLYKVTGIKQRLTIFIFSSDQIAEVSFLEITNNMLSTGEI-NLFKS 2867
            :|||:||.|...|:|||||.:...:|:..:.|:|:||.:||...||:|..|.:|:||:: |:|.:
Mouse  2412 YQIEITKNYTNSDWREDLKKIMLQSGVATKSTVFLFSDNQIKHESFVEDINMLLNTGDVPNIFPA 2476

  Fly  2868 DEFDELKPELERPAKKNG--VLLTTEALYSYFILNVRDFLHVALCFSPIGENFRSYIRQYPALLS 2930
            ||..:|..:::..|:..|  |..|..::|::||..||..||:.|..||||:.||:.:|.:|:|::
Mouse  2477 DEKADLVEKMQTAARTEGEKVEATPLSMYNFFIERVRKNLHIVLAMSPIGDAFRTRLRMFPSLIN 2541

  Fly  2931 STTPNWFRFWPQEALLEVASHFLIGFPLNVVVSGKEDEKHRESLVISTEAILQRDIAYVFSVIHS 2995
            ..|.:||:.||.:||..||:.||            ||        :..:..::.::..:......
Mouse  2542 CCTIDWFQSWPTDALELVANKFL------------ED--------VELDDNIRAEVVSMCKYFQE 2586

  Fly  2996 SVAKMSENMYAEVKRYNYVTSPNYLQLVSGFKKLLEKKRLEVSTASNRLRNGLSKISETQEKVSL 3060
            ||.|:|.:.|..:.|:||||..:||:|:..||.||..||.||.|..||...||.|:.....:|::
Mouse  2587 SVKKLSVDYYNTLLRHNYVTPTSYLELILTFKTLLNSKRQEVDTIRNRYLAGLQKLEFASSQVAV 2651

  Fly  3061 MSEELKASSEQVKILARECEDFISM---IEIQKSEATEQKEKVDAEAVLIRRDEIICLELAATAR 3122
            |..||.|...|   |.:..||...|   ||::..||       ||:.:|::.||......||.::
Mouse  2652 MQVELTALQPQ---LIQTSEDTAMMMVKIELETKEA-------DAKKLLVQADEKEANAAAAISQ 2706

  Fly  3123 A-------DLEVVMPMIDAAVKALDALNKKDISEVKSYGRPPMKIEKVMEAVLILLGKEPT---- 3176
            |       ||...||.::||:.|||.||..||:.|||...||..::.|||::.::.|.:|.
Mouse  2707 AIKNECEGDLAEAMPALEAALAALDTLNPSDITLVKSMQNPPGPVKLVMESICVMKGLKPERKPD 2771

  Fly  3177 -----------WENAKKVLSESTFLNDLKNFDRDHISDKTLKRI-AIYTKNPELEPDKVAVVSLA 3229
                       |..::|:|.:..||..||.:|:|:|....:||| ..:..:|:.:|..:..||.|
Mouse  2772 PSGSGKMIEDYWGVSRKILGDLKFLESLKTYDKDNIPSVIMKRIRERFIDHPDFQPAVIKNVSSA 2836

  Fly  3230 CKSLMQWIMAIENYGKVYRIVAPKQE-------KLDSAMKSLEEKQAALAAAKKKLEELQVVIEE 3287
            |:.|.:|:.|:|.|.:|.::||||:|       ||:..|:.|.:|:|.|...:.:|::|....|.
Mouse  2837 CEGLCKWVRAMEVYDRVAKVVAPKRERLREAEGKLEIQMQKLNQKRAELKLVEDRLQDLNDEFEL 2901

  Fly  3288 LYRQLEEKTNLLNELRAKEERLRKQLERAIILVESLSGERERWIETVNQLDLSFEKLPGDCLLSV 3352
            :.|:       .|.|....|...::|.||..|:..|.||::||.|...||.:.::.|.||.||:.
Mouse  2902 MNRK-------KNSLEKNIEICSQKLVRAEKLISGLGGEKDRWTEAARQLGIRYDNLTGDVLLAS 2959

  Fly  3353 AFMSYLGAFDTKYREELLVKWSLLIKDLLIPATLELKVTYFLVDAVSIREWNIQGLPADDLSTEN 3417
            ..::|||||...||.:...:|.:..||.:||.:::..::..|.|.:.||.|.|.|||.|..|.:|
Mouse  2960 GTVAYLGAFTVDYRAQCQNEWLVSCKDKVIPGSVDFSLSNTLGDPIKIRAWQIAGLPVDSFSVDN 3024

  Fly  3418 GVIVTQGSRWPLIIDPQMQANNWIKNMEERNQLMTLDFGMADYLRQLERALKEGLPVLLQNVGEY 3482
            |:||:...||||:||||.|||.|:||||:.|:|..:.|...:|:|.||.||:.|.||||:||||.
Mouse  3025 GIIVSNSRRWPLMIDPQGQANKWVKNMEKTNKLSVIKFSDTNYVRTLENALQFGTPVLLENVGEE 3089

  Fly  3483 LDQAINPILRQSFTIQSGERLLKFNDKYISYNNSFRFYITTKISNPHYPPEISSKTTIVNFALKQ 3547
            ||..|.|||.::...|.|...::..:..|.|:..|:|||||::.||||.||::.|..::||.:..
Mouse  3090 LDAFIEPILLKATFKQQGVEYMRLGENIIEYSREFKFYITTRLRNPHYLPEVAVKVCLLNFMITP 3154

  Fly  3548 DGLEAQLLGIIVRKEKPALEEQKDELVMTIARNKRTLIDLDNEILRLLNESRGSLLDDDELFSTL 3612
            .||:.|||||:..||||.|||:|::|::..|:||:.|.:::::||.:|:...|::|:|:.....|
Mouse  3155 LGLQDQLLGIVAAKEKPELEEKKNKLILESAQNKKQLKEIEDKILEVLSLCEGNILEDETAIKIL 3219

  Fly  3613 QKSRQTSVLVKESLSIAEVTEVEIDAARQEYKPASERASILFFVLMDMSKIDPMYVFSLAAYILL 3677
            ..|:..|..:.|...||.|||.:||..|..|||.:..::.:||.:.|::.|:|||.:||..:|.|
Mouse  3220 SSSKVLSEEISEKQEIASVTETQIDETRMGYKPVAVHSAAIFFCISDLAHIEPMYQYSLTWFINL 3284

  Fly  3678 FTQSIERSPRNQLVHERIQNINEYHSYAVYRNTCRGLFERHKLLFSIHMTAKILSNAGKLLEEEY 3742
            :.||:..|.::..:..||:.|.|:.:.::|.|.||.|||:.|||||:.:|..:|.....:.||.:
Mouse  3285 YVQSLANSNKSDELDLRIEYIIEHFTLSIYNNVCRSLFEKDKLLFSLLLTVGLLKERKAIDEEVW 3349

  Fly  3743 DFILKGGIVLDKLGQAPNPAPWWISEQNWDNITELDKVSGFHGIIDSFEQHYKAWNGWYATTFPE 3807
            .|:|.||:.||  ...|||||.|:||::|..|.....:....|:::...|:.|.|...|.:.:|.
Mouse  3350 YFLLTGGVALD--NPFPNPAPEWLSEKSWGEIVRASSLQKLKGLMEDVMQNIKVWKDIYDSAWPH 3412

  Fly  3808 QEDLVGEWNDKLTDFQKICVLRSLRPDRISFCLTQFIITKLGPRYVDPPVLDLKATFDESISQTP 3872
            :|.|...| ..|...:||.:||.||||:|...:..||...:|..:::.|..||:.::.:|....|
Mouse  3413 EESLPSPW-FFLQTLEKIAILRCLRPDKIVPAIQNFICETMGKIFIEAPTFDLQGSYGDSSCCVP 3476

  Fly  3873 LIFVLSPGVDPAQSLISLSESVKM-AQRMYSLSLGQGQAPIATKLIMDGIKDGNWVFLANCHLSL 3936
            |||:||||.||...|:..::.|.| ..:..::||||||.|||..:|...|.:|.||.|.||||:.
Mouse  3477 LIFILSPGADPMAGLLKFADDVSMGGTKTQTISLGQGQGPIAANMINKAIHEGTWVVLQNCHLAT 3541

  Fly  3937 SWMPTLDKMI-ATMQSMKLHKKFRLWLSSSPHPDFPISILQTSIKMTTEPPRGIKSNMKRLYNN- 3999
            ||||.|:|:. ..:.....:.:|||||:|.|...||:||||..||||.|||:|:::|:.|.|.|
Mouse  3542 SWMPALEKICEEVIVPENTNSEFRLWLTSYPSEKFPVSILQNGIKMTNEPPKGLRANLLRSYLND 3606

  Fly  4000 --INEANMENCSEPSKYKKLLFALCFFHTVLLERKKFLELGWNVIYSFNDSDFEVSEILLLLYLN 4062
              .:....::|::|..::||||.|||||.::.||:.:..||||:.|.||:||..:|...:.::||
Mouse  3607 PISDPLFFQSCTKPVIWQKLLFGLCFFHAIVQERRNYGALGWNIPYEFNESDLRISMRQIQMFLN 3671

  Fly  4063 EYEDTPWGALKYLIAGVNYGGHITDDWDRRLLITYINQFFCDQALQTRKFRLSTLPNYFIPDDGD 4127
            :||:.|:.||.||....||||.:|||.|||||::.::.|:|.: ::|..:.::....|.||..|.
Mouse  3672 DYEEVPFEALTYLTGECNYGGRVTDDKDRRLLLSLLSMFYCKE-IETDNYHIAPGDAYVIPPYGS 3735

  Fly  4128 VQSYLDQIQMFPNFDKPDAFGQHSNADIASLIGETRMLFEALLSMQVQTNSTSSNENGETKVFDL 4192
            .|||::.::..|....|:.||.|.||||.....||..||:.:| :.:...|..|.::.:..|.:|
Mouse  3736 YQSYIEYLRTLPITAHPEVFGLHENADITKDNQETNQLFQGVL-LTLPRQSGGSGKSPQEVVEEL 3799

  Fly  4193 AKEILMNTPDEINYEQTAKIIG-INRTPLEVVLLQEIERYNKLLVDMSTQLRDLRRGIQGLVVMS 4256
            |::||...|::.|.|:..|... :.:..:..||.||:.|:|:|...:...|.||.|.|:|.|:||
Mouse  3800 AQDILSKLPNDFNLEEVMKKYPVVYKESMNTVLRQELIRFNRLTKVVRRSLIDLGRAIKGQVLMS 3864

  Fly  4257 SDLEDIYLAVSEGRVPLQW-LKAYNSLKPLAAWARDLIHRVGHFNSWAKTLRPPILFWLAAYTFP 4320
            |:||:::.::..|:||..| .|:|.|||||..:..||:.|:..|..|... .||::||::.:.|.
Mouse  3865 SELEEVFNSMLVGKVPAMWAAKSYPSLKPLGGYVADLLARLTFFQEWIDK-GPPVVFWISGFYFT 3928

  Fly  4321 TGFVTAVLQTSARATKTPIDELSWDFYVFVEEDTAAARIIREGGGVYIRSLFLEGGGWLRKNQCL 4385
            ..|:|.|.|..||....|||.:.::|.|..:|.|  ...|.| .|.||:.|||||..|.|....:
Mouse  3929 QSFLTGVSQNYARKYTIPIDHIGFEFEVTPKETT--MENIPE-DGAYIKGLFLEGARWDRSTSQI 3990

  Fly  4386 QDPLPMELICPLPVIHFKPVENLKKRCRGVYQCPAYYYPVRSG---------SFVIAVDLKSGNE 4441
            .:.||..|..|||:|..||.|:.....:.:|.||.|....|.|         ::|::::|.: :.
Mouse  3991 GESLPKILYDPLPIIWLKPGESASFLHQDIYVCPVYKTSARRGILSTTGHSTNYVLSIELPT-DM 4054

  Fly  4442 KADYWIKRGTALLLSLAN 4459
            ...:||.||.|.|..|.|
Mouse  4055 PQKHWINRGVASLCQLDN 4072

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kl-2	NP_001015505.5	DHC_N1	178..749	CDD:285571	33/201 (16%)
		DHC_N2	1244..1646	CDD:285579	124/407 (30%)
		P-loop_NTPase	1785..2015	CDD:304359	138/229 (60%)
		P-loop_NTPase	2099..2242	CDD:304359	61/142 (43%)
		P-loop_NTPase	2401..2668	CDD:304359	100/286 (35%)
		P-loop_NTPase	2752..3030	CDD:304359	109/280 (39%)
		MT	3043..3373	CDD:289543	117/362 (32%)
		AAA_9	3402..3618	CDD:289547	98/215 (46%)
		Dynein_heavy	3760..4447	CDD:281078	260/702 (37%)
Dnah3	NP_001357735.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..37
		DHC_N2	824..1221	CDD:369852	124/413 (30%)
		DYN1	1018..3745	CDD:227570	1076/2821 (38%)
		AAA_6	1347..1673	CDD:372306	176/325 (54%)
		AAA 1. /evidence=ECO:0000250	1347..1568		136/220 (62%)
		AAA 2. /evidence=ECO:0000250	1628..1859		91/230 (40%)
		AAA 3. /evidence=ECO:0000250	1992..2240		93/278 (33%)
		AAA 4. /evidence=ECO:0000250	2351..2602		101/271 (37%)
		AAA_8	2360..2620	CDD:372310	109/279 (39%)
		Stalk. /evidence=ECO:0000250	2617..2916		103/315 (33%)
		AAA 5. /evidence=ECO:0000250	3001..3231		103/229 (45%)
		AAA 6. /evidence=ECO:0000250	3444..3668		93/223 (42%)
		Dynein_C	3767..4068	CDD:375627	104/306 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100025
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810