Protein Alignment kl-2 and CG9068

DIOPT Version :10

• Sequence 1: NP_001015505.5
• Gene: kl-2 / 3355181
• FlyBaseID: FBgn0001313
• Length: 4459
• Species: Drosophila melanogaster
• Sequence 2: NP_611111.1
• Gene: CG9068 / 36817
• FlyBaseID: FBgn0034106
• Length: 1227
• Species: Drosophila melanogaster
• Alignment Length: 1194
• Identity: 624/1194 - (52%)
• Similarity: 881/1194 - (73%)
• Gaps: 11/1194 - (0%)

  Fly     5 ETDRGS----EIAGLVEYVKKITFLYSLDHRDWNAKVINVISIWLINSTELVLTIFYDCDVLTGC 65
            ||.:.|    |:..||.|:::::.|..||||||....:::|..||:...|.:|||:||.|.|..|
  Fly    35 ETPKPSYSDEELNQLVGYIQRMSVLSCLDHRDWQEGTLDIIRGWLLEVHEPLLTIYYDRDALAAC 99

  Fly    66 LGFPVAPVIDLCYFIRSSKEIISIHSFHDMVNFGTVQDDVDGCLLKILELIYAPIFRNFMEWGDN 130
            ||.|...|.||.||.|...||.|:..|||.:||||:..||||||:::|:.:|.|.|||::||...
  Fly   100 LGMPSMCVSDLSYFRREPNEIFSVEGFHDEINFGTLTSDVDGCLMELLDRLYVPFFRNYLEWNAT 164

  Fly   131 VKQRFCTSLDKFLGILTAIYFKMSGMTVLYVPYVVKEIAKEISSYDREFVKNLECIAVSWATLIR 195
            |:.|||:|:|:||..|:.::.::|||:|:|||:|:||:.  ....||..|.:||.||:.|.|.||
  Fly   165 VRNRFCSSMDRFLAFLSGMHHQISGMSVMYVPFVIKELT--AGPVDRYLVGSLEGIALYWTTQIR 227

  Fly   196 ILLNDKTLTSPNEYISVGDEFEFWLYRFEVLQGLNAQLDQVDVQQIIRVLRSTHSVYIKQIDELI 260
            .||.|.|||.|::.::|.||||||.||:|||||:|.||...|||:::.:|.:..||::.|:|.||
  Fly   228 TLLADDTLTVPHDLVTVRDEFEFWEYRYEVLQGINDQLAHSDVQKVLLLLHNAQSVHMPQMDGLI 292

  Fly   261 FESTHELMEAMENIKFLHLLMQPCSQLDFSESPTFVSQLIPRTIHLIRFIWLNSEQYNRRDLITG 325
            ..:..||.:::.|||:||||::|||::|.:.||..:::|:||.||||||||||||.||...||..
  Fly   293 ERARKELHKSLSNIKYLHLLIEPCSKIDAATSPADLTKLLPRIIHLIRFIWLNSEYYNTTRLIAA 357

  Fly   326 IFRNLSNQIIRFCTEKVNVEKILSGSSRFGIKICNMCIDCCLTYKGIYDIMSKTHAKINIRIGWS 390
            :|||||||||||||::..||:||||..||||:|||:.|:|||||:||||.:|:..|:.:.::.|.
  Fly   358 LFRNLSNQIIRFCTKQTKVEEILSGKPRFGIRICNVAIECCLTYRGIYDTISRDLAQKHTQMPWE 422

  Fly   391 LDNAMIFNHVDAFMERLNDVIDICESMMVFGRLDESESIPKPQFGGTSGTEFEATADNVENEFLV 455
            ||..:||||:|||:|||||||||||||:|||||||:.|||||.||||.|.|.|..|::||.:||.
  Fly   423 LDEGLIFNHIDAFVERLNDVIDICESMIVFGRLDENGSIPKPVFGGTCGEELEKIAESVEVQFLD 487

  Fly   456 TLTALCTDSKEIILNVHKNEWYEEVIKYRRTVQSMEETVQRLMSNVFQHICNVEEALESLNVMIF 520
            ||..|..:|:..|||||:.:||.:|..:|:.:|.:|||||||:.||||.:.||||.||:|..|:|
  Fly   488 TLNKLQQNSQAYILNVHRADWYADVAGFRKNMQKLEETVQRLIFNVFQQVSNVEEMLEALQAMLF 552

  Fly   521 YSY--RSTIRKTFLRQVSSAWVFFSNEIDSSVHMLMDRSKMHESWVPYYASRALGYRVHLDRLVW 583
            |||  |.|:|||:|::.|..|..||.|:|::...|:: .:..|||:..:.|.|||||::|:||.|
  Fly   553 YSYRQRGTLRKTYLKETSKLWRMFSKEMDATSRKLLE-EQSRESWLSKHVSIALGYRINLERLTW 616

  Fly   584 LCNRLNSSDWLPNVSEASVVLKKFESVRREFDKEVKKSFDEWQKNCCSLL--LNQKLDRYLLIRS 646
            |.:||.:|:|||.|.|:|..|.||:::|.||.||::.::|:|...||...  |.|:|||||::||
  Fly   617 LRDRLKNSEWLPAVKESSPALAKFDALRHEFQKEIRLAYDDWVAKCCGFSGDLCQRLDRYLVVRS 681

  Fly   647 KKKKGLIECNIDRTILTICEQAQHFERLGLGVPGMVRKIYEKHETLRFVYNSVVQVCLNYNHILS 711
            ||.|||:|||||.::|.:|||||||||:|..:|..::|:||:::|:|.:||.::::.|::|.||:
  Fly   682 KKFKGLLECNIDASVLELCEQAQHFERMGFAIPSTMKKLYERYDTIRSLYNGIIKLALSHNRILA 746

  Fly   712 ALSEQERKLFRALIQACDRKIAPGVFKLTYGGELSDAYIADCAKHTNKLQETMDIYKRAIQNIAR 776
            .||::||||||.|||||||::||||||:|||.|.::.:..|..:...:.||.:.|:|||.:.:||
  Fly   747 VLSDRERKLFRPLIQACDRQLAPGVFKITYGSEFNEEFFEDGTEFIAEFQELVLIFKRANRGVAR 811

  Fly   777 FCEKICDTPMLKFNFSGAVTISIFENHLSSYLRRVSNILRGFYSTITDLIFAVFKEFQAVIEDMP 841
            .|||||.|.:|.|.|||:|.||:|:..|||.|....:|||.:||.:.:|:.|...:||:|.::|.
  Fly   812 ICEKICGTCLLHFAFSGSVDISVFQQQLSSRLSSSGDILRSYYSHVVELLSAFSGQFQSVDDEMS 876

  Fly   842 IEWYGFVNVFDDMLATAFLTSSKNSLNMLTNALHRDPDMAAAPILVMESDVRERCIVLTPDIDVI 906
            .||..:||..|||||::.:||::.|||.|..|||.|.|||:|||:|:||||::..||.|||:|.|
  Fly   877 AEWIAYVNDMDDMLASSLMTSARGSLNKLYEALHCDADMASAPIIVVESDVKDGRIVFTPDMDAI 941

  Fly   907 ANLLSGYIDRIHNILEQFPRIGIKMKLPKEHQYESFSKAFLEDSESTQLICNIEAEINHEREEID 971
            .::::|.:|.|.::|:||||:|.|:||||:.|.:.|:..|.||.|.::|:.:|:|||..:|||:.
  Fly   942 GDMINGIVDSIRSMLDQFPRLGYKLKLPKKQQRQGFASVFREDQECSELMRSIQAEIGIQREELA 1006

  Fly   972 GYITFWNSHRMLWETTELEFTKRVKATQMTADIFEASIEYYSAMADDISYVDAITHVYFILMNQN 1036
            .|.:.||.:|:||:|||.||.:|:.:...||.:||..||:|||:|||:.:.||||:|||||:|||
  Fly  1007 KYESEWNKNRVLWQTTEEEFRQRLMSKSRTAGVFEGGIEHYSALADDVIFEDAITNVYFILINQN 1071

  Fly  1037 YIKSSILDCIEKWQALNIKILLSHSFSLIRAIYRYMRKNERKMMMVPRTLKESLLAKQFFERIIN 1101
            .:||::||.||||||||||:||.|..:|:.|:|||||:|||.:|.||||::|::.|||.||:::.
  Fly  1072 ALKSTMLDWIEKWQALNIKMLLDHGSNLMGAVYRYMRRNERNVMKVPRTIRETVAAKQLFEKLLK 1136

  Fly  1102 EVPLKQAGFPPTLELFAILDKYQVEIPEEIRVKVIGLEAAWHHYLKRLGEADEMLDNNREEFKKI 1166
            :||:||:.|.|.||||.:|.||||::.||...:|:|||.||.|||:.|.||||||||...|.|.:
  Fly  1137 DVPVKQSAFTPMLELFVLLHKYQVKLSEETFEQVMGLETAWLHYLQVLEEADEMLDNEDSEAKLL 1201

  Fly  1167 LVQQAEKFKIILKEFLDDFFLKLP 1190
            |.:..||||:|||:||:||:.|||
  Fly  1202 LAKHGEKFKLILKDFLEDFYSKLP 1225

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kl-2	NP_001015505.5	DHC_N1	180..749	CDD:462457	314/572 (55%)
		DHC_N2	1238..1646	CDD:462462
		DYN1	<1478..4135	CDD:227570
		AAA_6	1785..2111	CDD:463697
		Dynein_C	4161..4455	CDD:465677
CG9068	NP_611111.1	DHC_N1	212..784	CDD:462457	314/572 (55%)