DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment kl-2 and Dnah9

DIOPT Version :9

Sequence 1:	NP_001015505.5	Gene:	kl-2 / 3355181	FlyBaseID:	FBgn0001313	Length:	4459	Species:	Drosophila melanogaster
Sequence 2:	NP_001093103.1	Gene:	Dnah9 / 237806	MGIID:	1289279	Length:	4484	Species:	Mus musculus

Alignment Length:	4600	Identity:	1418/4600 - (30%)
Similarity:	2305/4600 - (50%)	Gaps:	390/4600 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 VLTGCLGFPVAPVIDL-----------CYFIRSSKEIISIHSFHDMVNFGTVQDDVDGCLLKILE 114
            |.:|..|..|.|.:|.           .:|:|:..|....||....|..|.:.......|..:|.
Mouse    72 VQSGPGGLVVTPGLDAGPEPSRARAKGLFFLRTKSEPPGNHSLRGTVLCGDLPAVPLEHLAPLLS 136

  Fly   115 LIYAPIF---RNFMEWGDNVKQRFCTSLDKFLGILTAIYFKMSGMTVLYVPYVVKEI------AK 170
            .:..|:.   :|.:||...|.|............|..|:..|.|.|:|.:|...:::      ::
Mouse   137 EVIIPVLANEKNHLEWPHMVCQDIRHHAHTLKSDLLVIFEHMKGRTLLPLPVGSEKLEFVDGHSE 201

  Fly   171 EIS-SYDREFVKNLECIAVSWATLIRILLNDKT----LTSPNEYISVGDEFEFWLYRFEVLQGLN 230
            .:| :.|:..:..:|...:.|:..::::|..::    :...|....|  |.|||..|.|.|:.:.
Mouse   202 PVSDAIDKSTLYAVESAVIKWSHQVQVVLKRESSQALIQGQNPTPKV--ELEFWKSRCEDLEHIY 264

  Fly   231 AQLDQVDVQQIIRVLRSTHSVYIKQIDELIFESTHELMEAMENIKFLHLLMQPCSQ-LDFSES-- 292
            .||..:.|:.:..:|....|.|:.....:..:....|.||.:    :|:.:.|..| ||..|:
Mouse   265 NQLMTIKVKGMAELLDKLQSSYLPAFKAMFRDVEAALTEAQD----IHVHLLPLQQHLDILENVE 325

  Fly   293 -PTFVSQLIPRTIHLIRFIWLNSEQYNRRDLITGIFRNLSNQIIRFCTEKVNVEKILSGSSRFGI 356
             |....:|.| .:|::..||...:.|.....:|.:.:.:.|.:|:..:..::.|.:|........
Mouse   326 FPKVKGRLRP-LLHVVCLIWATCKWYRSPGRLTVLLQEICNLLIQQASNYLSPEDLLRSEVEESQ 389

  Fly   357 KICNMCIDCCLTYKGIY-DIMSKTHAKI----NIRIGWSLDNAMIFNHVDAFMERLNDVIDICES 416
            |...:..|....:|..: |.....|...    .:|: |....:::|..:|.|:.|::.|.|:.::
Mouse   390 KKLQVVSDTLSFFKQAFQDRREHLHTYFKEDSEVRV-WDFQASLVFVRLDGFLGRVHMVEDLLKT 453

  Fly   417 MMVFGRLDESESIPKPQFGGTSGTEFEATADNVENEF------LVTLTALCTDSKEIILNVHKNE 475
            .:....|:      |.:|.|..|.........:..||      .:..:..|.|.|       ..|
Mouse   454 ALDLNNLE------KLEFSGLRGNSLSQKVQRMHEEFEEMYKVFLDCSYDCLDPK-------GTE 505

  Fly   476 WYEEVIKYRRTVQSMEETVQRLMSNVFQHICNVEEALESLNVM------------IFYSYRSTIR 528
            :..:|.::.:.|:.::..:..::...|....:||.|.:.|::.            :...|.:.||
Mouse   506 FENDVCEFNKRVEDLDRRLGTILIQAFDDAPDVEHAFKLLDITGTLIKRPLVAQDVSQKYLALIR 570

  Fly   529 KTFLRQVSSAWVFFSNEID-------SSVHMLMDRSKMHESWVPYYASRALGYRVHLDRLVWLCN 586
             .|..::.:..|.:|..|.       |.||..|........|......|..|
Mouse   571 -MFSTELDAVRVIYSQHIQKEAEHGFSPVHKNMPTMAGGICWAQELRQRVKG------------- 621

  Fly   587 RLNSSDWLPNV----SEASVVLKKFESVRREFDKEVKKSFDEWQKNCCSLLLNQ---KLDRYLLI 644
            ...:...:|::    :|...:::|:|.:....::..::.:::|    |..:..:   .|...||.
Mouse   622 PFGNFKNIPHLYLQSAEGKRMIQKYEDLLSLLEEYERRLYEDW----CQTVSEKSQYNLSLPLLH 682

  Fly   645 RSKKKKGLIECNIDRTILTICEQAQHFERLGLGVPGMVRKIYEKHETL---RFVYNSVV---QVC 703
            |....|.| ..|.:..::::.::..:.:      |..|:.|.|....:   |..|..:|   ::.
Mouse   683 RDPNTKQL-SVNFNPQLISVLKEMNYLQ------PSEVKTIPETAAAMFSSREFYRQLVANLELM 740

  Fly   704 LN-YNHILSALSEQERKLFRALIQACDRKIAPGVFKLTYGGELSDAYIADCAKH-TN-------K 759
            .| ||.::..|.|.|..|....:|..|.::......|::..|    .|.|.|.. ||       :
Mouse   741 ANWYNKVIKILLEVEFPLVEEELQNIDLRLRAAEETLSWKTE----GIWDYAMQITNSIHDLEQR 801

  Fly   760 LQETMDIYKRAIQNIARFCEKICDTPMLKFNFSG----AVTISIFENHLSSYLRRVSNILRGFYS 820
            :|:|.|..:. ||||.    |...:|:.| ...|    .:::...::|:..|           ||
Mouse   802 IQKTKDNVEE-IQNIM----KTWVSPIFK-RKDGKKEWPLSLDDQQDHMEKY-----------YS 849

  Fly   821 TITD---LIFAVFKEFQAVIEDMPIE--WYGFVNVFDDMLATAFLTSSKNSLNMLTNALHRDPDM 880
            .|.:   .|.|:.:|...:....|..  |..:||..|.||...|..:.:.||..|.......|.:
Mouse   850 LIQESGLKIHALVQENLVLFAADPASSIWKSYVNYIDSMLLDGFFLAIECSLKYLLENTECKPGL 914

  Fly   881 AAAPILVMESDVRERCIVLTPDIDV-----IANLLSGYIDRIHNILEQFPRIGIKMKLPKEHQYE 940
              .|:...:.::....:|..|.:|.     :.:::...:.||..:....||:       ..|...
Mouse   915 --TPVFEAQLNLVTPELVFHPSLDSGVKGGLYDIVQSLVTRIFAMPSLVPRL-------SPHSGS 970

  Fly   941 SFSKAFLED-----------SESTQ----LICNIEAEIN-------HEREEIDGYITFWNSHRML 983
            ...:..|||           .|..|    |.|.....::       .:|:||.|....: .|.:.
Mouse   971 PHYQGDLEDMADLAGLRSVLMERVQNMMTLCCGYRNTLSQYSYLYVEDRKEILGQFLLY-GHVLT 1034

  Fly   984 WETTELEFTKRVKATQMTADIFEASIEYYSAMADDISYVDAITHVY--FILMNQNYIKSSILDCI 1046
            .|..|......:.........|:..|:.|..:.:::..::. |.|:  ::.::....|:|:|:.|
Mouse  1035 PEEIEAHAEDGIPENPPLLHHFKDQIDSYEKLYEEVVSLEP-TKVFDGWMRVDVRPFKASLLNTI 1098

  Fly  1047 EKWQALNIKIL-------LSHSFSLIRAIYRYMRKNERK--------MMMVPRTLKE-SLLAKQF 1095
            :||..:..:.|       ||...|.||:....:.|...|        :|....|||| .......
Mouse  1099 KKWSLMFKQHLVDFVTNSLSDLDSFIRSTESGLLKRVEKGDFQGLVEIMGHLVTLKERQSSTDDM 1163

  Fly  1096 FERIINEVPLKQAGFPPTLELFAILDKYQVEIPEEIRVKVIGLEAAWHHYLKRLG---------- 1150
            ||      ||||     |:||   |..|:.|:||.:..::..|...|.: :|::.
Mouse  1164 FE------PLKQ-----TIEL---LKSYEQELPETVFKQLEELPEKWKN-MKKMAITVRQQVAPL 1213

  Fly  1151 EADEMLDNNREEFKKILVQQAEKFKIILKEFLDDFFLKLP-TSANINPRIALKFLRIIALKIEDC 1214
            :|:|:         .:|.|:...|....::|.:.|..:.| ...:|||.   :.|....::|:..
Mouse  1214 QANEV---------ALLRQRCSAFDDEQQQFQERFRKEAPFRFDSINPH---QMLDAWHVEIQHM 1266

  Fly  1215 FTFEESLMRDLAVFNVNQPESIDLRKLDFEVRIVKNIWELIFEWQTNWEGWKKGYFWKMNINEME 1279
            .:...::.:...:|.||.|:...||:...|...:|.:|:.|....::...|:...:..:::..|:
Mouse  1267 ESTMATISKSADLFEVNVPDYKQLRQCRKEACQLKELWDTIGMVTSSIRAWEATSWRNISVEAMD 1331

  Fly  1280 DTALNLYKEFTTLNKKFYDRHWEM---LEATTKNVDSFRRTLPLITALKNPCMRERHWNRVRDVI 1341
            .......:....|:|:|  |.|:.   ||:|..|.   ..:|..:..|:||.:|:|||.::....
Mouse  1332 SECKQFARHIRNLDKEF--RSWDAFTGLESTVLNT---LTSLRAVAELQNPAIRDRHWRQLMQAT 1391

  Fly  1342 HVNFDENSKNFTLELIINLDFQAFSEDIQDISNPATMELQIENSIKNIATIWKKQSFEMAFY-HD 1405
            .|||..| ::.||..::.|....|.::::.|.:.|..|:.:|.::|.:.|.|....|:...: ..
Mouse  1392 GVNFTMN-QDTTLAHLLQLQLHHFEDEVRGIVDRAVKEMSMEKTLKELQTTWASMEFQYESHART 1455

  Fly  1406 GIYRIKNVEDCFQLLEEHMVQISAMKATRFVEPFITIVDYWEKTLSYISETLEKGLTVQRQWLYL 1470
            .:..:::.||..::||::.||:..:..:::|..|:..|..|:|.||.....:.....|||.|.:|
Mouse  1456 RVPLLQSDEDLIEVLEDNQVQLQNLMMSKYVAFFLEEVSSWQKKLSTADSVISIWFEVQRTWSHL 1520

  Fly  1471 ENIFQG-DDIRKQLPEEAKRFATITEEFRTISSKMFQAKTAVKATNLRPPPFLLNRFSRMDERLE 1534
            |:||.| :|||.|||:::|||..|..:||.::....:....|:|||   ...|..:...:..||.
Mouse  1521 ESIFIGSEDIRAQLPQDSKRFEGIDSDFRELAYDAQKTPNVVEATN---KSGLYEKLEDIQSRLC 1582

  Fly  1535 LIQRALEIYLEAKRQLFPRFYFISNDDLLEILGNSKRPDLVQTHLKKLFDNLYKLELKRVGKTLS 1599
            |.::||..||:.||..||||||:|:.|||:||.|...|..||.||.|||||:.|::.:.......
Mouse  1583 LCEKALAEYLDTKRLSFPRFYFLSSSDLLDILSNGTAPQQVQRHLSKLFDNMAKMQFQLDASQNP 1647

  Fly  1600 RWQASGMHSDDGEYVEFMMVIYIDGPSERWLKQVEEYMLVVMKEMLKLTRGSLKKLVGNREKWIS 1664
            ...:.||:|.:.|||.|.......|..|.||.:|..:|...::.  ::|.|........|::|:.
Mouse  1648 TKTSLGMYSKEEEYVAFSEACDCSGQVEIWLNRVLRHMKATVRH--EMTEGVTAYEEKPRDQWLF 1710

  Fly  1665 LWPGQMVLTTAQIQWTTECTRSLIHCSMVDQ--KKPLRKLKKKQIKVLSKLSEMSRKDLTKTMRL 1727
            .:|.|:.||..||.||||..   |..:.:::  :..::...|||:..|..|..|....|:|..|.
Mouse  1711 DYPAQVALTCTQIWWTTEVG---IAFARLEEGYESAMKDYYKKQVAQLKTLITMLIGPLSKGDRQ 1772

  Fly  1728 KVNTLITLEIHGRDVIERMYKSNCKDTGHFEWFSQLRFYWHRESELCVIRQTNTEHWYGYEYTGN 1792
            |:.|:.|:::|.|||:.:|......:...|.|.||||..|..|::.|.....:.:..|.|||.||
Mouse  1773 KIMTICTIDVHARDVVAKMIAQKVDNAQAFLWLSQLRHRWDDEAKHCFANICDAQFLYSYEYLGN 1837

  Fly  1793 SGRLVITPLTDRCYITLTTALHLHRGGSPKGPAGTGKTETVKDLGKALGIWVIVTNCSEGLDYKS 1857
            :.||||||||||||||||.:|||...|:|.||||||||||.||||:||||.|.|.||||.:||||
Mouse  1838 TPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGIMVYVFNCSEQMDYKS 1902

  Fly  1858 IGKNFSGLAQSGCWGCFDEFNRINIEVLSVVAQQIMSIMAALSTKALELMFEGQMIKLKHTVGLF 1922
            .|..:.||||:|.||||||||||::|||||||.|:.||..|:..|.....|.|:.|.|..:||:|
Mouse  1903 CGNIYKGLAQTGAWGCFDEFNRISVEVLSVVAVQVKSIQDAIRDKKQRFSFLGEEISLDPSVGIF 1967

  Fly  1923 ITMNPGYAGRTELPDNLKSMFRPISMMVPDNIIIAENLLFSDGFTNTRNLARKVYTLYELAKQQL 1987
            ||||||||||||||:|||::|||.:|:|||..:|:|.:|.::||...|.||||..|||.|.|:.|
Mouse  1968 ITMNPGYAGRTELPENLKALFRPCAMVVPDFELISEIMLVAEGFIEARLLARKFITLYRLCKELL 2032

  Fly  1988 SKQYHYDFGLRSMVALLRYAGRKRRQLPNTTEEEIVYLAMKDMNVARLTANDLPLFNGIMSDIFP 2052
            |||.|||:|||::.::|..||..:|..|:..|::::..:::|.|:.::..:|:|:|.|::.|:||
Mouse  2033 SKQDHYDWGLRAIKSVLVVAGSLKRGDPDRPEDQVLMRSLRDFNIPKIVTDDMPVFMGLIGDLFP 2097

  Fly  2053 GVSLPTIDYSEFNIAIYEEFREAGLQPITIAVKKVIELFETKNSRHSVMIIGDTGTAKSVTWRTL 2117
            .:.:|.....:|...:.:...:..||.....|.||::|.|....||||.::|..||.||...|:|
Mouse  2098 ALDVPRKRDLDFEAVVRKAIVDLKLQAEDNFVLKVVQLEELLAVRHSVFVVGGAGTGKSQVLRSL 2162

  Fly  2118 QNCFYRMNSQRFSGWEAVTVYPVNPKALNLAELYGEYNLSTGEWLDGVLSSIMRIICGDEEPTQK 2182
            ...:..|  :|...|.     .:||||:...||:|..|.:|.||.||:.|||||.:........|
Mouse  2163 HKTYQIM--RRRPVWT-----DLNPKAVTNDELFGIINPATREWKDGLFSSIMRELAIISHDGPK 2220

  Fly  2183 WLLFDGPVDAVWIENMNSVMDDNKLLTLVNSERITMPVQVSLLFEVGDLAVASPATVSRCGMVYN 2247
            |:|.||.:|.:|||::|:||||||:|||.::|||.:...:.||||:..|..|:||||||.|::|.
Mouse  2221 WILLDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNPTMRLLFEISHLRTATPATVSRAGILYI 2285

  Fly  2248 DYNDWGWKPFVNSWLQRLRIKEFADFLRIHFDYMVPKILDFKRMRCKEPVRTNELNGVVSLCKLL 2312
            :..|.||.|.|:||:.:..::.....|.|.||..:|..||..|.|.|:.:...|.:.:..||.||
Mouse  2286 NPADLGWNPPVSSWIDQREVQTERANLTILFDKYLPTCLDTLRTRFKKIIPVPEQSMIQMLCYLL 2350

  Fly  2313 EIFGTKVNGINPINLELLEEMTRLWFMFCLVWSICSSVDEDSRQRLDS-------FIRELESC-F 2369
            |...||    ..|..:..:|:..|:|:|..:|:..|:|.:|  |.:|.       ::.|.::. |
Mouse  2351 ECLLTK----EDIPADCPKEIYELYFVFAAIWAFGSAVIQD--QLVDYRAEFSKWWLTEFKTVKF 2409

  Fly  2370 PIKDTVFDYFVDPNERTFLPWDSKLLSSWKCDFESPFYKIIVPTGDTVRYEYVVSKLLAEEYPVM 2434
            |.:.|||||::||..:.|.|| :||:..::.|.|.|....:|.|.:|:|..|.:.:|:....|||
Mouse  2410 PSQGTVFDYYIDPETKKFEPW-AKLIPQFEFDPEMPLQACLVHTSETIRVCYFMERLMQWRRPVM 2473

  Fly  2435 LVGNVGTGKTSTAISVMEACDKNKFCILAVNMSAQTTAAGLQESIENRTEKRTKTQFVPIGGKRM 2499
            |||..|:||:....:.:.:.:..::.:..|..:..||:|.||..:|...||:....:.|.|.:::
Mouse  2474 LVGPAGSGKSVLVGAKLSSLNPEEYMVKNVPFNYYTTSAMLQAVLEKPLEKKAGRNYGPPGNRKL 2538

  Fly  2500 ICFMDDFNMPAKDIYGSQPPLELIRQWIDYKYWFNRKTQQKIYVQNTLLMAAMGPPGGGRQTISS 2564
            |.|:||.|||..|.||:..|..:|||.:||.:|::|.......:.|...::.|.|..|. .||:.
Mouse  2539 IYFIDDMNMPEVDAYGTVQPHTVIRQHLDYGHWYDRNKLSLKEIMNVQYISCMNPTAGS-FTINP 2602

  Fly  2565 RTQSRFVLLNLTFPSQETIIRIFGTMLCQKLE--SYPNEVREMWLPITLCTINLYVSMISKMLPT 2627
            |.|..|.:..|.||..:.:..|:.|:|...|:  ::|..:::...|:....:..:..:.:..|||
Mouse  2603 RLQRHFSVFALCFPGADALSSIYSTILTHHLKFGNFPTTLQKSIPPLINLAVTFHQKIATTFLPT 2667

  Fly  2628 PNKSHYLFNLRDISKVFQGLLRSEKELQNKKNFFLRLWVHECFRVFSDRLVDDSDQFWFVNTIND 2692
            ..|.||:|||||.:.:|||:|.|..|........::|::||..||:.|::|::.|...|.....:
Mouse  2668 AIKFHYIFNLRDFANIFQGILFSSVECVKSTQDLVKLYLHESSRVYRDKMVEEKDFNLFDKIQTE 2732

  Fly  2693 ILGKHFEVTFHSLCPSKVPPFFGDFAHPQGFYEDLQV---DFLRTFMKNQLEEYNNFPGMTRMNL 2754
            .|.|:|:.:...|..::....:..||:..|..:.:.|   |.|...:...||.:|....:  |:|
Mouse  2733 FLKKNFDDSEEVLKQTQNLNMYCHFANGIGEPKYMPVQSWDLLNQTLVEALESHNEVNAV--MDL 2795

  Fly  2755 VFFREAIEHIVRILRVISQPRGHILNMGIGGSGRQVLTKLAAFILEMAVFQIEVTKKYKTGDFRE 2819
            |.|.:||.||..|.|::..|||:.|.:|:||||:|.||||||||..|.||||.:.|.|:..||:.
Mouse  2796 VLFEDAIRHICHINRILESPRGNALLVGVGGSGKQSLTKLAAFISSMDVFQITLRKGYQIPDFKV 2860

  Fly  2820 DLKNLYKVTGIKQRLTIFIFSSDQIAEVSFLEITNNMLSTGEI-NLFKSDEFDELKPELERPAKK 2883
            ||.:|....|:|...|:|:.:...:|:..||.:.|::|::||| :|:..:|.:.:...:....|.
Mouse  2861 DLASLCLKAGVKNLSTVFLMTDAHVADERFLVLINDLLASGEIPDLYSDEEEENIINNVRNEVKS 2925

  Fly  2884 NGVLLTTEALYSYFILNVRDFLHVALCFSPIGENFRSYIRQYPALLSSTTPNWFRFWPQEALLEV 2948
            .|::.:.|..:.:||..|:..|.|.|||||:|...|...|::||:::.|..|||..||||||..|
Mouse  2926 QGLMDSRENCWKFFIERVQRQLKVTLCFSPVGNKLRIRSRKFPAIVNCTAINWFHEWPQEALESV 2990

  Fly  2949 ASHFLIGFPLNVVVSGKEDEKHRESLVISTEAILQRDIAYVFSVIHSSVAKMSENMYAEVKRYNY 3013
            :..||            ::.|:.|..|       ::.|:...:.:|.||.|.|::.....:||||
Mouse  2991 SLRFL------------QNTKNIEPAV-------KQSISKFMAFVHISVNKTSQSYLTNEQRYNY 3036

  Fly  3014 VTSPNYLQLVSGFKKLLEKKRLEVSTASNRLRNGLSKISETQEKVSLMSEELKASSEQVKILARE 3078
            .|..::|:.:..::.|||:...|:.....||.|||.|:..|..:|..:..:|.....:::....:
Mouse  3037 TTPKSFLEFIRLYQSLLERNGKELQAKVERLENGLLKLHSTSAQVDDLKAKLATQEVELRHKNED 3101

  Fly  3079 CEDFISMIEIQKSEATEQKEKVDAEAVLIRRDEIICLELAATAR---ADLEVVMPMIDAAVKALD 3140
            .:..|.::.::.|:.:.:|...|.|.   ::..:|.||:....:   .||....|.:.||..||:
Mouse  3102 TDKLIQVVGVETSKVSREKAIADEEE---QKVALIMLEVQQKQKDCEEDLAKAEPALTAAQAALN 3163

  Fly  3141 ALNKKDISEVKSYGRPPMKIEKVMEAVLILL---GKEP---TWENAKKVLSE-STFLNDLKNFDR 3198
            .|||.:::|:||:|.||:.:..|..||::|:   ||.|   :|:.||..::: .:||:.|.:||:
Mouse  3164 TLNKTNLTELKSFGSPPLAVSNVSAAVMVLMAPGGKVPKDRSWKAAKITMAKVDSFLDSLIHFDK 3228

  Fly  3199 DHISDKTLKRIAIYTKNPELEPDKVAVVSLACKSLMQWIMAIENYGKVYRIVAPKQEKLDSAMKS 3263
            ::|.:..||.|..|.::|...|:.||..|.|...|..|::.|..:.:|:..|.||::.|:.|...
Mouse  3229 ENIHENCLKAIRPYLQDPAFNPEFVATKSYAAAGLCSWVINIVRFYEVFCDVEPKRQALNKATSD 3293

  Fly  3264 LEEKQAALAAAKKKLEELQVVIEELYRQLEEKTNLLNELRAKEERLRKQLERAII---------L 3319
            |...|..|||.|.|:..|...:.:|..:.|         :|..|:|:.|.|..:.         |
Mouse  3294 LTTAQEKLAAIKAKITHLNENLAKLTTKFE---------KATAEKLKCQQEAELTAGTISLANRL 3349

  Fly  3320 VESLSGERERWIETVNQLDLSFEKLPGDCLLSVAFMSYLGAFDTKYREELL-VKWSLLIKDLL-- 3381
            |..|:.|..||.|.|.........|.||.||:.||:||||.|..|||:.|: ..|...:..|.
Mouse  3350 VGGLASENIRWAEAVQNFRQQERTLCGDILLTTAFISYLGFFTKKYRKSLMDGTWRPYLSQLKVP 3414

  Fly  3382 IPATLELKVTYFLVDAVSIREWNIQGLPADDLSTENGVIVTQGSRWPLIIDPQMQANNWIKNMEE 3446
            ||.|..|.....|.|...:..|..:|||||.:|.||..|:....||||::|||:|...|||| :.
Mouse  3415 IPTTPTLDPLRMLTDDAEVAAWQNEGLPADRMSMENATILINCERWPLMVDPQLQGIKWIKN-KY 3478

  Fly  3447 RNQLMTLDFGMADYLRQLERALKEGLPVLLQNVGEYLDQAINPILRQSFTIQSGERLLKFNDKYI 3511
            ..:|.....|....|:.:||||:.|..||::|:.|.:|..:.|:|.:. .|:.| |.:|..||..
Mouse  3479 GEELRVTQIGQKGCLQTIERALEAGDVVLIENLEESIDPVLGPLLGRE-VIKKG-RFIKIGDKEC 3541

  Fly  3512 SYNNSFRFYITTKISNPHYPPEISSKTTIVNFALKQDGLEAQLLGIIVRKEKPALEEQKDELVMT 3576
            .:|..||..:.||::||||.||:.::.|::||.:.:||||.|||..:|..|:|.||:.|.:|...
Mouse  3542 EFNPKFRLILHTKLANPHYQPELQAQATLINFTVTRDGLEDQLLAAVVSMERPDLEQLKSDLTKQ 3606

  Fly  3577 IARNKRTLIDLDNEILRLLNESRGSLLDDDELFSTLQKSRQTSVLVKESLSIAEVTEVEIDAARQ 3641
            ....|.||..|::.:|..|:.:.|:.|.:..|...|:.::||:..|:|.:..|::|||:|:.||:
Mouse  3607 QNGFKITLKTLEDNLLSRLSSASGNFLGETALVENLEVTKQTAADVEEKVQEAKLTEVKINEARE 3671

  Fly  3642 EYKPASERASILFFVLMDMSKIDPMYVFSLAAYILLFTQSIERSPRNQLVHERIQNINEYHSYAV 3706
            .|:||:.|||:|:|::.|:|||.|||.|||.|:.::|.:::|::..::.|.||:.|:.:..:::|
Mouse  3672 HYRPAAARASLLYFIMNDLSKIHPMYQFSLKAFSIVFQKAVEKAAPSESVTERVTNLIDSITFSV 3736

  Fly  3707 YRNTCRGLFERHKLLFSIHMTAKILSNAGKLLEEEYDFILKGGIVLDKLGQAPNPAPW-WISEQN 3770
            |:.|.|||||..||.:...:|.:||....::...|.||:|:..:      |...|:|. ::|.|.
Mouse  3737 YQYTTRGLFECDKLTYLAQLTFQILLVNQEVNAAELDFLLRAPV------QTGTPSPMEFLSHQA 3795

  Fly  3771 WDNITELDKVSGFHGIIDSFEQHYKAWNGWYATTFPEQEDLVGEWNDKLTDFQKICVLRSLRPDR 3835
            |..|..|..:..|..:....|...|:|..:..:..||:|....||.:| |..|::|::|::||||
Mouse  3796 WGGIKALSSMEEFCNLDRDIEGSAKSWKKFVESECPEKEKFPQEWKNK-TALQRLCMMRAMRPDR 3859

  Fly  3836 ISFCLTQFIITKLGPRYVDPPVLDLKATFDESISQTPLIFVLSPGVDPAQSLISLSESVKMA--- 3897
            :::.:..|:..|||.:||....||...:|:||...||:.|:|||||||.:.:.:..:.:...
Mouse  3860 MTYAMRDFVEEKLGSKYVMGRALDFVTSFEESGPATPMFFILSPGVDPLKDVENQGKKLGYTFNN 3924

  Fly  3898 QRMYSLSLGQGQAPIATKLIMDGIKDGNWVFLANCHLSLSWMPTLDKMIATMQSMKLHKKFRLWL 3962
            :..:::||||||..:|...:....|.|:||.|.|.||...|:.||:|.:..: |.:.|..||:::
Mouse  3925 RNFHNVSLGQGQEVVAEAALDLAAKKGHWVILQNIHLVAKWLSTLEKKLEEL-SEESHPDFRVFI 3988

  Fly  3963 SSSPHPD-----FPISILQTSIKMTTEPPRGIKSNMKRLYNNINEANMENCSEPSKYKKLLFALC 4022
            |:.|.|.     .|..||:.|||:|.|||.|:.:|:.:..:|..:..:|.||..:::|.:|||||
Mouse  3989 SAEPAPSPEGHIIPQGILENSIKITNEPPTGMHANLHKALDNFTQDTLEMCSRETEFKTILFALC 4053

  Fly  4023 FFHTVLLERKKFLELGWNVIYSFNDSDFEVSEILLLLYLNEYEDTPWGALKYLIAGVNYGGHITD 4087
            :||.|:.||:||...|||..|.||..|..:|..:|..:|......|:..|:||...:.|||||||
Mouse  4054 YFHAVVAERRKFGPQGWNRSYPFNTGDLTISVNVLYNFLEANTKVPYDDLRYLFGEIMYGGHITD 4118

  Fly  4088 DWDRRLLITYINQFFCDQALQTRKFRLSTLPNYFIPDDGDVQSYLDQIQMFPNFDKPDAFGQHSN 4152
            ||||||..||:.:|...:.|:.   .||..|.:.:|.:.|...|...|......:.|..:|.|.|
Mouse  4119 DWDRRLCRTYLEEFIRPEMLEG---ELSLAPGFPLPGNMDYSGYHQYIDAELPPESPYLYGLHPN 4180

  Fly  4153 ADIASLIGETRMLFEALLSMQVQTNSTSSNENG---ETKVFDLAKEILMNTPDEINY-EQTAKII 4213
            |:|..|...:..||..:|.||.: :|.:.:..|   |.||....:|||....||.|. |..||:
Mouse  4181 AEIGFLTQTSEKLFRTVLEMQPR-DSQAGDGAGITREEKVKTFLEEILDRMTDEFNIAELMAKV- 4243

  Fly  4214 GINRTPLEVVLLQEIERYNKLLVDMSTQLRDLRRGIQGLVVMSSDLEDIYLAVSEGRVPLQWL-K 4277
             ..|||..||.|||.||.|.|..::...||:|..|:||.:.|:|::|::..|:....||..|. :
Mouse  4244 -EERTPYIVVALQECERMNILTREIQRSLRELHLGLQGELTMTSEMENLQNALYLDVVPESWARR 4307

  Fly  4278 AYNSLKPLAAWARDLIHRVGHFNSWAKTLRPPILFWLAAYTFPTGFVTAVLQTSARATKTPIDEL 4342
            ||.|...||||..||::|:....||......|...||..:..|..|:||::|:.||..:.|:|::
Mouse  4308 AYPSTAGLAAWFLDLLNRIKELESWTGDFLMPSTVWLTGFFNPQSFLTAIMQSMARKNEWPLDQM 4372

  Fly  4343 SWDFYVFVEEDTAAARIIREGGGVYIRSLFLEGGGWLRKNQCLQDPLPMELICPLPVIHFKPVEN 4407
            :....|..:.........||  |.||..||:||..|..:...:.:....:|..|:||:..|.:..
Mouse  4373 ALQCDVTKKNREEFRSPPRE--GAYIYGLFMEGACWDTQTGIIAEAKLKDLTPPMPVMFLKAIPA 4435

  Fly  4408 LKKRCRGVYQCPAYYYPVRSGSFVIAVDLKSGNEKADYWIKRGTALLLSL 4457
            .|:.||.||.||.|....|..::|...:||: .|....|:..|.||||.:
Mouse  4436 DKQDCRSVYACPVYKTCQRGPTYVWTFNLKT-KENPSKWVLAGVALLLQI 4484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kl-2	NP_001015505.5	DHC_N1	178..749	CDD:285571	115/622 (18%)
		DHC_N2	1244..1646	CDD:285579	124/406 (31%)
		P-loop_NTPase	1785..2015	CDD:304359	143/229 (62%)
		P-loop_NTPase	2099..2242	CDD:304359	63/142 (44%)
		P-loop_NTPase	2401..2668	CDD:304359	83/268 (31%)
		P-loop_NTPase	2752..3030	CDD:304359	100/278 (36%)
		MT	3043..3373	CDD:289543	107/349 (31%)
		AAA_9	3402..3618	CDD:289547	81/215 (38%)
		Dynein_heavy	3760..4447	CDD:281078	243/700 (35%)
Dnah9	NP_001093103.1	DHC_N1	210..787	CDD:285571	116/626 (19%)
		DHC_N2	1293..1697	CDD:285579	125/414 (30%)
		P-loop_NTPase	1830..2060	CDD:304359	143/229 (62%)
		P-loop_NTPase	2144..2279	CDD:304359	62/141 (44%)
		P-loop_NTPase	2437..2708	CDD:304359	83/271 (31%)
		P-loop_NTPase	2786..3053	CDD:304359	101/287 (35%)
		MT	3065..3408	CDD:289543	108/354 (31%)
		AAA_9	3436..3648	CDD:289547	81/214 (38%)
		Dynein_heavy	3785..4474	CDD:281078	243/699 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1492at2759
OrthoFinder	1	1.000	-	-		FOG0000396
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100025
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820