Protein Alignment kl-2 and Dync1h1

DIOPT Version :9

• Sequence 1: NP_001015505.5
• Gene: kl-2 / 3355181
• FlyBaseID: FBgn0001313
• Length: 4459
• Species: Drosophila melanogaster
• Sequence 2: NP_084514.2
• Gene: Dync1h1 / 13424
• MGIID: 103147
• Length: 4644
• Species: Mus musculus
• Alignment Length: 4823
• Identity: 1185/4823 - (24%)
• Similarity: 2147/4823 - (44%)
• Gaps: 783/4823 - (16%)

  Fly     6 TDRGSEI----------AGLVEYVKKITFLYSLDHRDWNAKVINVISIWL------------INS 48
            ||.|.::          :|:..::::|..:..||....:...:..||.||            ..|
Mouse   228 TDFGDKVEDPTFLNQLQSGVNRWIREIQKVTKLDRDPASGTALQEISFWLNLERALYRIQEKRES 292

  Fly    49 TELVLTIFYDCDVLTGCLGFPVAPVIDLCYFIRSSKEIISIHSFHDMVNFGTVQDDVDGCLLKIL 113
            .|::||:    |:|                  :..|.      ||..|:|     |.|..|.:.|
Mouse   293 PEVLLTL----DIL------------------KHGKR------FHATVSF-----DTDTGLKQAL 324

  Fly   114 ELI--YAPIFRNFMEWGDNVKQRFCTSLDKFLGILTAIYFKMSGMTVLYVPY-----VVKEIAKE 171
            |.:  |.|:.::| ...|.:.   .|.|||....|.||:..:..:.....|.     :|:.|:::
Mouse   325 ETVNDYNPLMKDF-PLNDLLS---ATELDKIRQALVAIFTHLRKIRNTKYPIQRALRLVEAISRD 385

  Fly   172 ISSYDREFVKNLECIAVSWATLIRILLNDKTLTSPNEYISVGDEFEFWLYRFEVLQGLNAQLDQV 236
            :||...:.:...:.:.|::....:::            ::..:.|:.|...:|.||.|...:.:.
Mouse   386 LSSQLLKVLGTRKLMHVAYEEFEKVM------------VACFEVFQTWDDEYEKLQVLLRDIVKR 438

  Fly   237 DVQQIIRV---LRSTHSVYIKQIDEL-IFESTHELMEAMENIKFLHLLMQPCSQLDFSESPTFVS 297
            ..::.:::   :...|.....::|:: .|...||.:.|: .::.|...:...:|.:..|:|.
Mouse   439 KREENLKMVWRINPAHRKLQARLDQMRKFRRQHEQLRAV-IVRVLRPQVTAVAQQNQGEAPE--- 499

  Fly   298 QLIPRTIHLIRFIWLNSEQYNRRDLITGIFRNLSNQIIRFCTEKVNVEKILSGSSRFGIKICNMC 362
               |:.:.:...:      ::..|         :|.|     |:||
Mouse   500 ---PQDMKVAEVL------FDAAD---------ANAI-----EEVN------------------- 522

  Fly   363 IDCCLTYKGIYDI----MSKTHAKINIRIGWSLDNAMIFNHVDAFMERLNDVIDICESMMVFGRL 423
                |.|:.:.::    :||...:     .|           :|.|:|.::.||..|: .:..||
Mouse   523 ----LAYENVKEVDGLDVSKEGTE-----AW-----------EAAMKRYDERIDRVET-RITARL 566

  Fly   424 DESESIPKPQFGGTSGTEFEATADNVENEFLVTLTALCTDSKEIILNVHKNEWYEEVIKYRRTVQ 488
                   :.|.|         ||.|....|     .:.:....:.:..|          .|..::
Mouse   567 -------RDQLG---------TAKNANEMF-----RIFSRFNALFVRPH----------IRGAIR 600

  Fly   489 SME-ETVQRLMSNVFQHICNVEEALESLN--VMIFYSYRSTIRKTFLRQVS--SAWVFFSNEIDS 548
            ..: :.:||           |::.:|||:  ..:.|......:.:.:|.:.  |..:.::.:||.
Mouse   601 EYQTQLIQR-----------VKDDIESLHDKFKVQYPQSQACKMSHVRDLPPVSGSIIWAKQIDR 654

  Fly   549 SVHMLMDRSK--MHESWVPYYASRALGYRVHLDRLVWLCNRLNSSDWLPNVSEASVVLKKFESVR 611
            .:...|.|.:  :.:.|                               .|..|...:.:..:|.|
Mouse   655 QLTAYMKRVEDVLGKGW-------------------------------ENHVEGQKLKQDGDSFR 688

  Fly   612 REFDKEVKKSFDEWQKNCCSLLLNQKLDRYLLIRSKKKKG------LIECNIDRTILTICEQAQH 670
            .:.:  .::.||:|.:......|... .|...|.|.:.:|      .::.|....|:|:.::.::
Mouse   689 MKLN--TQEIFDDWARKVQQRNLGVS-GRIFTIESARVRGRTGNVLKLKVNFLPEIITLSKEVRN 750

  Fly   671 FERLGLGVP-GMVRKIYEKHETLRFVYNSVVQVCLNYNHILSALSEQERKLFRALIQACDRK--- 731
            .:.||..|| .:|.|.::.::...|.. |:::....|......:  :||.....|:....::
Mouse   751 LKWLGFRVPLAIVNKAHQANQLYPFAI-SLIESVRTYERTCEKV--EERNTISLLVAGLKKEVQA 812

  Fly   732 -IAPGVFKLTYGGELSDAYIADCAKHTNKLQETMDIYKRAIQNIARFCEKICDTPMLKFNFSGAV 795
             ||.|: .|.:.....|.|:                 :|..:.:..|.||:.|
Mouse   813 LIAEGI-ALVWESYKLDPYV-----------------QRLAETVFNFQEKVDD------------ 847

  Fly   796 TISIFENHLSSYLRRVSNILRGFYSTITDLIFAVFKEFQAVIEDMPIEWYG----FVNVFDDMLA 856
             :.|.|..:...:|.:...:.. :.|.::::..|    |..::|:.:..|.    :||..|..:.
Mouse   848 -LLIIEEKIDLEVRSLETCMYD-HKTFSEILNRV----QKAVDDLNLHSYSNLPIWVNKLDMEIE 906

  Fly   857 --------------TAFL---TSSKNSLNMLTNALHRDPDMAAAP-------ILVMESDVRERCI 897
                          |..|   ...|..::|.|:|    |.::..|       .:|.|..:..:.|
Mouse   907 RILGVRLQAGLRAWTQVLLGQAEDKAEVDMDTDA----PQVSHKPGGEPKIKNVVHELRITNQVI 967

  Fly   898 VLTPDIDVIANLLSGYIDRIHNILEQFPRI-------GIKMKLPKEHQYESFSKAFLED-----S 950
            .|.|.|:.....|...:.....::...|||       |:..:|.:|.::...:...:.|     .
Mouse   968 YLNPPIEECRYKLYQEMFAWKMVVLSLPRIQSQRYQVGVHYELTEEEKFYRNALTRMPDGPVALE 1032

  Fly   951 ESTQLICNIEAEINHEREEIDGYITFWNSHRMLWETTELEFTKRVKATQMTADIFEASIEYYSAM 1015
            ||...:..|..       |::.|:..|..::.||:              |.|:      ..|:.:
Mouse  1033 ESYSAVMGIVT-------EVEQYVKVWLQYQCLWD--------------MQAE------NIYNRL 1070

  Fly  1016 ADDI---------------SYVDAITHVYF--ILMNQNYIKSSILDCIEKW---------QALNI 1054
            .:|:               ::.:|.|...|  ::::...::|.:....:.|         |.|..
Mouse  1071 GEDLNKWQALLVQIRKARGTFDNAETKKEFGPVVIDYGKVQSKVNLKYDSWHKEVLSKFGQMLGS 1135

  Fly  1055 KILLSHS-FSLIR-----------------AIYRYMRKNERKMMMVPRTLK-----ESLLAKQFF 1096
            .:...|| .|..|                 ....|::..:||:....:.::     :.||.||.|
Mouse  1136 NMTEFHSQISKSRQELEQHSVDTASTSDAVTFITYVQSLKRKIKQFEKQVELYRNGQRLLEKQRF 1200

  Fly  1097 ERIINEVPLKQAGFPPTLELFAILDKYQVEIPEEIRVKVIGLEAAWHHYLKRLGEADEMLDNNRE 1161
            :            |||:   :..:|               .:|..|..:...:...|..:.....
Mouse  1201 Q------------FPPS---WLYID---------------NIEGEWGAFNDIMRRKDSAIQQQVA 1235

  Fly  1162 EFKKILVQQAEKFKIILKEFLDDFFLKLPTSANINPRIALKFLRIIALKI-------EDCFTFEE 1219
            ..:..:||:....:....:.|.|:....|.:.|:.|..||:.|.|...|.       |.|...:|
Mouse  1236 NLQMKIVQEDRAVESRTTDLLTDWEKTKPVTGNLRPEEALQALTIYEGKFGRLKDDREKCAKAKE 1300

  Fly  1220 SL-MRDLAVFNVNQPESIDLRKLDFEVRIVKNIW-ELIFEW----QTNWEGWKKGYFWKMNINEM 1278
            :| :.|..:.:.:: |.:.: .|: |::.:|.:| ||...|    |...:.|......|:..|
Mouse  1301 ALELTDTGLLSGSE-ERVQV-ALE-ELQDLKGVWSELSKVWEQIDQMKEQPWVSVQPRKLRQN-- 1360

  Fly  1279 EDTALNLYKEFTTLNKKFYDRHWEMLEATTKNVDSFRRTLPLITALKNPCMRERHWNRVRDVIHV 1343
            .|..||..|.|....:::  ..:|.::...|   .:.:...|:..||:..:::|||.::...:||
Mouse  1361 LDGLLNQLKNFPARLRQY--ASYEFVQRLLK---GYMKINMLVIELKSEALKDRHWKQLMKRLHV 1420

  Fly  1344 NFDENSKNFTLELIINLDFQAFSEDIQDISNPATMELQIENSIKNIATIWKKQSFEMAFYHDGIY 1408
            |:..:  ..||..|.::|.|.....::|:...|..|:.:|..:|.|..:|.....::..|.:...
Mouse  1421 NWVVS--ELTLGQIWDVDLQKNEAVVKDVLLVAQGEMALEEFLKQIREVWNTYELDLVNYQNKCR 1483

  Fly  1409 RIKNVEDCFQLLEEHMVQISAMKATRFVEPFITIVDYWEKTLSYISETLEKGLTVQRQWLYLENI 1473
            .|:..:|.|..::||:..:||||.:.:.:.|......||..|:.|....:..:.|||:|:|||.|
Mouse  1484 LIRGWDDLFNKVKEHINSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGI 1548

  Fly  1474 FQGD-DIRKQLPEEAKRFATITEEFRTISSKMFQAKTAVKATNLRPPPFLLNRFSRMDERLELIQ 1537
            |.|. ||:..||.|.:||.:|:.||..:..|:.::...:...|::.   :.....|:.:.|..||
Mouse  1549 FTGSADIKHLLPVETQRFQSISTEFLALMKKVSKSPLVMDVLNIQG---VQRSLERLADLLGKIQ 1610

  Fly  1538 RALEIYLEAKRQLFPRFYFISNDDLLEILGNSKRPDLVQTHLKKLFDNLYKLELKRVGKTLSRWQ 1602
            :||..|||.:|..||||||:.::|||||:||||....:|.|.||:|..:..:.|......:
Mouse  1611 KALGEYLERERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNEDNSVV---- 1671

  Fly  1603 ASGMHSDDGEYVEFMMVIYI-DGPS-ERWLKQVEEYMLVVMKEML--KLTR----GSLKKLVGNR 1659
             .|:.|.:||.|.|...:.| :.|. ..||..||:.|.|.:.::|  .:|.    |....:..|.
Mouse  1672 -LGISSREGEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGKATSIDPNT 1735

  Fly  1660 E-KWISLWPGQMVLTTAQIQWTTECTRSLIHCSMVDQKKPLRKLKKKQIKVLSKLSEMSRKDLTK 1723
            . .||..:..|:|:.:|||.|:.....:|.:........||:.:.......|:.|::....:...
Mouse  1736 YITWIDKYQAQLVVLSAQIAWSENVENALSNVGGGGDVGPLQSVLSNVEVTLNVLADSVLMEQPP 1800

  Fly  1724 TMRLKVNTLITLEIHGRDVIERMYKSNCKDTGHFEWFSQLRFYWHRES----ELCVIRQTNTEHW 1784
            ..|.|:..|||..:|.|||...:.||...:...|||.||:|||:..:.    :...|:..|.:..
Mouse  1801 LRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQMANAKFN 1865

  Fly  1785 YGYEYTGNSGRLVITPLTDRCYITLTTALHLHRGGSPKGPAGTGKTETVKDLGKALGIWVIVTNC 1849
            ||:||.|...:||.||||||||:|:|.||....||||.|||||||||:||.||..||.:|:|.||
Mouse  1866 YGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNC 1930

  Fly  1850 SEGLDYKSIGKNFSGLAQSGCWGCFDEFNRINIEVLSVVAQQIMSIMAAL---------STKA-- 1903
            .|..|::::|:.|.||.|.|.|||||||||:...:||.|:||:..|..||         .|.|
Mouse  1931 DETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQEALREHSNPNYDKTSAPI 1995

  Fly  1904 -LELMFEGQMIKLKHTVGLFITMNPGYAGRTELPDNLKSMFRPISMMVPDNIIIAENLLFSDGFT 1967
             .||:  .:.:|:...:.:|||||||||||:.||||||.:||.::|..||..:||:.:|:|.||.
Mouse  1996 TCELL--NKQVKVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFR 2058

  Fly  1968 NTRNLARKVYTLYELAKQQLSKQYHYDFGLRSMVALLRYAGRKRRQ------------------- 2013
            ....||.|:...::|..:|||.|.|||||||::.::|..||..:|:
Mouse  2059 TAEVLANKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVSAGNVKRERIQKIKREKEERGEAVDEG 2123

  Fly  2014 --LPNTTEEEIVYLAMKDMNVARLTANDLPLFNGIMSDIFPGVSLPTIDYSEFNIAIYEEFREA- 2075
              ..|..|:||:..::.:..|.:|.|.|:||...::||:||||.....:.:    |:.||.::.
Mouse  2124 EIAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPGVQYHRGEMT----ALREELKKVC 2184

  Fly  2076 ---------GLQPITIAVKKVIELFETKNSRHSVMIIGDTGTAKSVTWRTLQNCFYRMNSQRFSG 2131
                     |.:...:.|:||::|::.....|.:|::|.:|:.||:.||.|....     :|..|
Mouse  2185 QEMYLTYGDGEEVGGMWVEKVLQLYQITQINHGLMMVGPSGSGKSMAWRVLLKAL-----ERLEG 2244

  Fly  2132 WEAVTVYPVNPKALNLAELYGEYNLSTGEWLDGVLSSIMRIICGD---EEPTQKWLLFDGPVDAV 2193
            .|.| .:.::|||::...|||..:.:|.||.||:.:.::|.|..:   |...::|::|||.||..
Mouse  2245 VEGV-AHIIDPKAISKDHLYGTLDPNTREWTDGLFTHVLRKIIDNVRGELQKRQWIVFDGDVDPE 2308

  Fly  2194 WIENMNSVMDDNKLLTLVNSERITMPVQVSLLFEVGDLAVASPATVSRCGMVYNDYNDWGWKPFV 2258
            |:||:|||:||||||||.|.||:::|..|.::|||.||..|:.|||||||||:...:........
Mouse  2309 WVENLNSVLDDNKLLTLPNGERLSLPPNVRIMFEVQDLKYATLATVSRCGMVWFSEDVLSTDMIF 2373

  Fly  2259 NSWLQRLR---IKEFAD-------------------FLRIHFD---------------------- 2279
            |::|.|||   :.|..|                   .|:|..|
Mouse  2374 NNFLARLRSIPLDEGEDEAQRRRKGKEDEGEEAASPMLQIQRDAATIMQPYFTSNGLVTKALEHA 2438

  Fly  2280 YMVPKILDFKRMRCKEPVRTNELNGVVSLCKLLEIFGTKVNGIN------PINLELLEEMTRLWF 2338
            :.:..|:|..|:||           :.||..:|......|...|      |:.:|.||...:.:.
Mouse  2439 FKLEHIMDLTRLRC-----------LGSLFSMLHQACRNVAQYNANHPDFPMQIEQLERYIQRYL 2492

  Fly  2339 MFCLVWSICSSVDEDSRQRLDSFIRELESCFPIKDT----VFDYFVDPNERTFLPWDSKLLSSWK 2399
            ::.::||:........|..|..:||.: :..|:...    :.||.|..:.. :.||.:|:
Mouse  2493 VYAILWSLSGDSRLKMRAELGEYIRRI-TTVPLPTAPNVPIIDYEVSISGE-WSPWQAKV----- 2550

  Fly  2400 CDFESPFYK-----IIVPTGDTVRYEYVVSKLLAEEYPVMLVGNVGTGKTSTAISVMEACDKNKF 2459
            ...|...:|     ::|||.||||:|.::...|||..|::|.|..|:|||.|..|.:.|....:
Mouse  2551 PQIEVETHKVAAPDVVVPTLDTVRHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDME- 2614

  Fly  2460 CILAVNMSAQTTAAGLQESIENRTE-KRTKTQFV--PIG-GKRMICFMDDFNMPAKDIYGSQPPL 2520
             ::.:|.|:.||...|.::.::..| :||....|  |:. ||.::.|.|:.|:|..|.||:|..:
Mouse  2615 -VVGLNFSSATTPELLLKTFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVI 2678

  Fly  2521 ELIRQWIDYKYWFNRKTQQKIYVQNTLLMAAMGPP-GGGRQTISSRTQSRFVLLNLTFPSQETII 2584
            ..|||.:::..::....|..:.::....:.|..|| ..||:.:|.|......::.:.:|...::.
Mouse  2679 SFIRQMVEHGGFYRTSDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLT 2743

  Fly  2585 RIFGTMLCQKLESYPNEVREMWLPITLCTINLYVSMISKMLPTPNKSHYLFNLRDISKVFQGLLR 2649
            :|:||.....|...|: :|....|:|...:..| :|..:......:.||:::.|::::..:|:..
Mouse  2744 QIYGTFNRAMLRLIPS-LRTYAEPLTAAMVEFY-TMSQERFTQDTQPHYIYSPREMTRWVRGIFE 2806

  Fly  2650 SEKELQN-KKNFFLRLWVHECFRVFSDRLVDDSDQFWFVNTINDILGKHFEVTFHSLCPSKVPPF 2713
            :.:.|:. .....:|:|.||..|:|.||||:|.::.|....|:.:..|||.........|: |..
Mouse  2807 ALRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTDENIDMVALKHFPNIDKEKAMSR-PIL 2870

  Fly  2714 FGDFAHPQGFYEDLQVDFLRTFMKNQL----EEYNNFPGMTRMNLVFFREAIEHIVRILRVISQP 2774
            :.::....  |..:..:.||.::|.:|    ||..:.|      ||.|.|.::|::||.|:..||
Mouse  2871 YSNWLSKD--YIPVDQEELRDYVKARLKVFYEEELDVP------LVLFNEVLDHVLRIDRIFRQP 2927

  Fly  2775 RGHILNMGIGGSGRQVLTKLAAFILEMAVFQIEVTKKYKTGDFREDLKNLYKVTGIKQRLTIFIF 2839
            :||:|.:|:.|:|:..|::..|::..::|:||:|.:||...||.|||:.:.:.:|.|.....||.
Mouse  2928 QGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIM 2992

  Fly  2840 SSDQIAEVSFLEITNNMLSTGEI-NLFKSDEFDELKPELERPAKKNGVLLTT-EALYSYFILNVR 2902
            ....:.:..|||..|.:|:.||: .||:.||:..|..:.:..|:|.|::|.: |.||.:|...|.
Mouse  2993 DESNVLDSGFLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQKEGLMLDSHEELYKWFTSQVI 3057

  Fly  2903 DFLHVALCFSPIGENFRSYIRQYPALLSSTTPNWFRFWPQEALLEVASHFLIGFPL---NVVVSG 2964
            ..|||....:|..|..:......|||.:....|||..|..|||.:|...|.....|   |.:|..
Mouse  3058 RNLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNYIVPD 3122

  Fly  2965 ---------KEDEKHRESLVISTEAILQRDIAYVFSVIHSSVAKMSENMYAEVKRYNYVTSPNYL 3020
                     .:...|||::|.|        ..:|...:|.:.|::::    ...|...:|..:||
Mouse  3123 YMPVVYDKLPQPPTHREAIVNS--------CVFVHQTLHQANARLAK----RGGRTMAITPRHYL 3175

  Fly  3021 QLVSGFKKLLEKKRLEVSTASNRLRNGLSKISETQEKVSLMSEELKASSEQVKILARECEDFISM 3085
            ..::.:..|..:||.|:......|..||.||.||.::|..:..:|:..|:::::......|.:..
Mouse  3176 DFINHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKK 3240

  Fly  3086 IEIQKSEATEQKEKVDAEAV---LIRRDEIICLELAATARADLEVVMPMIDAAVKALDALNKKDI 3147
            :...:.||  :|:||.::.:   |.::.|:|. :...:.:.||:.|.|.:..|..|:.::.|:.:
Mouse  3241 MVKDQQEA--EKKKVMSQEIQEQLHKQQEVIA-DKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHL 3302

  Fly  3148 SEVKSYGRPPMKIEKVMEAVLILLGKEPT-WENAKKVLSESTFLNDLKNFDRDHISDKTLKRI-A 3210
            .||:|...||..::..:|::.:|||:..| |:..:.::....|:..:.||..:.|||...::: .
Mouse  3303 VEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVNFSAEEISDAIREKMKK 3367

  Fly  3211 IYTKNPELEPDKVAVVSLACKSLMQWIMAIENYGKVYRIVAPKQEKLDSAMKSLEEKQAALAAAK 3275
            .|..||....:.|...||||..:::|.:|..||..:.:.|.|.:.:|.......::.|
Mouse  3368 NYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQ------- 3425

  Fly  3276 KKLEELQVVIEEL----YRQLEEKTNLLNE---LRAKEERLRKQLERAIILVESLSGERERWIET 3333
            :|..|::.:|.:|    .|..||...|::|   ::|....:..::.|:..|::|||.|||||.:|
Mouse  3426 QKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKT 3490

  Fly  3334 VNQLDLSFEKLPGDCLLSVAFMSYLGAFDTKYREELLVKWSLLIKDLLIPATLELKVTYFLVDAV 3398
            ..........:.||||||.||::|.|.||.:.|:.|...||..::...|....::..|.:|.:|.
Mouse  3491 SETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQANIQFRTDIARTEYLSNAD 3555

  Fly  3399 SIREWNIQGLPADDLSTENGVIVTQGSRWPLIIDPQMQANNWIKNMEERNQLMTLDFGMADYLRQ 3463
            ....|....||||||.|||.:::.:.:|:||||||..||..:|.|..:..::....|....:.:.
Mouse  3556 ERLRWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIMNEYKDRKITRTSFLDDAFRKN 3620

  Fly  3464 LERALKEGLPVLLQNVGEYLDQAINPILRQSFTIQSGERLLKFNDKYISYNNSFRFYITTKISNP 3528
            ||.||:.|.|:|:|:|..| |..:||:|.:......|..|:...|:.|..:.||..:::|:....
Mouse  3621 LESALRFGNPLLVQDVESY-DPVLNPVLNREVRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTV 3684

  Fly  3529 HYPPEISSKTTIVNFALKQDGLEAQLLGIIVRKEKPALEEQKDELVMTIARNKRTLIDLDNEILR 3593
            .:||::.|:.|.|||.:.:..|::|.|..:::.|:|.::|::.:|:......:..|..|:..:|:
Mouse  3685 EFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEKRSDLLKLQGEFQLRLRQLEKSLLQ 3749

  Fly  3594 LLNESRGSLLDDDELFSTLQKSRQTSVLVKESLSIAEVTEVEIDAARQEYKPASERASILFFVLM 3658
            .|||.:|.:||||.:.:||:..::.:..|...:...::...|::...|:|.|.|...|.::|.:.
Mouse  3750 ALNEVKGRILDDDTIITTLENLKREAAEVTRKVEETDIVMQEVETVSQQYLPLSTACSSIYFTME 3814

  Fly  3659 DMSKIDPMYVFSLAAYILLFTQSIERSP--RNQLVH-ERIQNINEYHSYAVYRNTCRGLFERHKL 3720
            .:.::..:|.:||..::.::...:..:|  :....| :|:..|.:......:....||:..:..:
Mouse  3815 SLKQVHFLYQYSLQFFLDIYHNVLYENPNLKGATDHTQRLSIITKDLFQVAFNRVARGMLHQDHI 3879

  Fly  3721 LFSIHMT-AKILSNAGK-LLEEEYDFILKGGIVLDKLGQAPNPAPWWISEQNWDNITELDKVSGF 3783
            .|::.:. .|:....|: ..:.|:...|:|..::...|..|...  .::.:..:.:..|..:..|
Mouse  3880 TFAMLLARIKLKGTVGEPTYDAEFQHFLRGKEIVLSAGSTPKIQ--GLTVEQAEAVVRLSCLPAF 3942

  Fly  3784 HGIIDSFEQHYKAWNGWYATTFPEQEDLVGEWNDKLTD------FQKICVLRSLRPDRISFCLTQ 3842
            ..:|... |..:.:..|..::.||| .:...|:::...      ..::.::::.||||:......
Mouse  3943 KDLIAKV-QADEQFGIWLDSSSPEQ-TVPYLWSEETPTTPIGQAIHRLLLIQAFRPDRLLAMAHM 4005

  Fly  3843 FIITKLGPRY---VDPPVLDLKATFDESIS-QTPLIFVLSPGVDPAQSLISLSESVKMAQRMYSL 3903
            |:.|.||..:   ::.| |||.......:. .||::....||.|.:..:..|  :.:...::.|:
Mouse  4006 FVSTNLGESFMSIMEQP-LDLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDL--AAEQNTQITSI 4067

  Fly  3904 SLGQGQA-PIATKLIMDGIKDGNWVFLANCHLSLSWMPTLDKMIATMQSMKLHKKFRLWLSSSPH 3967
            ::|..:. ..|.|.|...:|.|.||.|.|.||:..|:..|:|.:.::|.   |..|||:|:...:
Mouse  4068 AIGSAEGFNQADKAINTAVKSGRWVMLKNVHLAPGWLMQLEKKLHSLQP---HACFRLFLTMEIN 4129

  Fly  3968 PDFPISILQTSIKMTTEPPRGIKSNMKRLYNNINEANMENCSEPSKYKKLLFALCFFHTVLLERK 4032
            |..|:::|:.......|||.|:|:||.|.:::|..:.:  |..|::..:|.|.|.:||.::.||.
Mouse  4130 PKVPVNLLRAGRIFVFEPPPGVKANMLRTFSSIPVSRI--CKSPNERARLYFLLAWFHAIIQERL 4192

  Fly  4033 KFLELGWNVIYSFNDSDFEVSEILLLLYLNEY---------EDTPWGALKYLIAGVNYGGHITDD 4088
            ::..|||:..|.|.:||...:...:..:|::.         :..||.|||.|:|...|||.:.::
Mouse  4193 RYAPLGWSKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDNE 4257

  Fly  4089 WDRRLLITYINQFFCDQALQTRKFRLSTL----PNYFIPDDGDVQSYLDQIQMFPNFDKPDAFGQ 4149
            :|:|||.|::.:.|..::..: :|:|:..    .:..:||....:.::..:::.|:...|...|.
Mouse  4258 FDQRLLNTFLERLFTTRSFDS-EFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDAQTPSWLGL 4321

  Fly  4150 HSNADIASLIGETRMLFEALLSMQV----------------QTNSTSSNENGETK-VFDLAKEIL 4197
            .:||:...|..:...:...:|.||:                :|:|||.......: :...|...|
Mouse  4322 PNNAERVLLTTQGVDMISKMLKMQMLEDEDDLAYAETEKKARTDSTSDGRPAWMRTLHTTASNWL 4386

  Fly  4198 MNTPDEIN-YEQTAKIIGINRTPLEVVLLQEIERYNKLLVDMSTQLRDLRRGIQGLVVMSSDLED 4261
            ...|..:: .::|.:.|   :.||.....:|::...|||.|:...|.|:.:..:|....::.|..
Mouse  4387 HLIPQTLSPLKRTVENI---KDPLFRFFEREVKMGAKLLQDVRQDLADVVQVCEGKKKQTNYLRT 4448

  Fly  4262 IYLAVSEGRVPLQWLKAYN--SLKPLAAWARDLIHRVGHF--------NSWAKTLRPPILFWLAA 4316
            :...:.:|.:|..| ..|.  :...:..|..|...|:...        :..||.|: .|...|..
Mouse  4449 LINELVKGILPRSW-SHYTVPAGMTVIQWVSDFSERIKQLQNISQAAASGGAKELK-NIHVCLGG 4511

  Fly  4317 YTFPTGFVTAVLQTSARATKTPIDELSWDFYVFVEEDTAAARIIREGGGVYIRSLFLEGGGWLRK 4381
            ...|..::||..|..|:|....::||..:..|     ||:.....:.....:..|.|:|.
Mouse  4512 LFVPEAYITATRQYVAQANSWSLEELCLEVNV-----TASQSATLDACSFGVTGLKLQGA----- 4566

  Fly  4382 NQCLQDPLPM----ELICPLPVIHFKPVENLKKRCRGVYQCPAYYYPVRSGSFVIAVDLK-SGNE 4441
             .|..:.|.:    ..:.||..:.:....:.:|:. .|...|.|....|: ..:..||.: :..|
Mouse  4567 -TCSNNKLSLSNAISTVLPLTQLRWVKQTSAEKKA-SVVTLPVYLNFTRA-DLIFTVDFEIATKE 4628

  Fly  4442 KADYWIKRGTALL 4454
            ....:.:||.|:|
Mouse  4629 DPRSFYERGVAVL 4641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kl-2	NP_001015505.5	DHC_N1	178..749	CDD:285571	91/596 (15%)
		DHC_N2	1244..1646	CDD:285579	121/411 (29%)
		P-loop_NTPase	1785..2015	CDD:304359	119/262 (45%)
		P-loop_NTPase	2099..2242	CDD:304359	61/145 (42%)
		P-loop_NTPase	2401..2668	CDD:304359	72/277 (26%)
		P-loop_NTPase	2752..3030	CDD:304359	86/291 (30%)
		MT	3043..3373	CDD:289543	94/341 (28%)
		AAA_9	3402..3618	CDD:289547	70/215 (33%)
		Dynein_heavy	3760..4447	CDD:281078	165/743 (22%)
Dync1h1	NP_084514.2	Stem. /evidence=ECO:0000250	2..1865		388/1948 (20%)
		DHC_N1	238..830	CDD:285571	131/787 (17%)
		Interaction with DYNC1I2. /evidence=ECO:0000250	446..701		58/396 (15%)
		Interaction with DYNC1LI2. /evidence=ECO:0000250	649..800		31/187 (17%)
		DYN1	1044..4327	CDD:227570	943/3431 (27%)
		DHC_N2	1321..1719	CDD:285579	122/415 (29%)
		P-loop_NTPase	1866..2103	CDD:304359	118/238 (50%)
		AAA 1. /evidence=ECO:0000250	1866..2097		116/232 (50%)
		AAA 2. /evidence=ECO:0000250	2178..2450		86/277 (31%)
		P-loop_NTPase	2217..2357	CDD:304359	61/145 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2388..2408		1/19 (5%)
		AAA 3. /evidence=ECO:0000250	2554..2803		68/252 (27%)
		P-loop_NTPase	2565..2826	CDD:304359	70/264 (27%)
		AAA 4. /evidence=ECO:0000250	2897..3166		85/286 (30%)
		P-loop_NTPase	2907..3185	CDD:304359	86/289 (30%)
		Stalk. /evidence=ECO:0000250	3187..3498		83/320 (26%)
		MT	3199..3530	CDD:289543	94/340 (28%)
		AAA 5. /evidence=ECO:0000250	3551..3780		73/229 (32%)
		AAA_9	3559..3774	CDD:289547	70/215 (33%)
		Dynein_heavy	3920..4630	CDD:281078	166/740 (22%)
		AAA 6. /evidence=ECO:0000250	4003..4219		64/223 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100025
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810