Protein Alignment Ppr-Y and lrrc9

DIOPT Version :10

• Sequence 1: NP_001015502.3
• Gene: Ppr-Y / 3355180
• FlyBaseID: FBgn0046697
• Length: 569
• Species: Drosophila melanogaster
• Sequence 2: XP_017951824.1
• Gene: lrrc9 / 780204
• XenbaseID: XB-GENE-1011352
• Length: 1514
• Species: Xenopus tropicalis
• Alignment Length: 591
• Identity: 125/591 - (21%)
• Similarity: 218/591 - (36%)
• Gaps: 185/591 - (31%)

  Fly    60 QILTMRLEFNNILRIDHLWILPNLTKLCLNCNKIETIENIEMLTNLKDLNLSFNFIEKIENLDTL 124
            :|.::.|:..|::||.:|..|.||.....:.|.:..||.:|...||::|||..|.|.|:|.|..|
 Frog   896 KITSLTLDSQNLVRITNLEKLVNLRWASFSSNHLTKIEGLEHCVNLEELNLDDNSISKLEGLSKL 960

  Fly   125 VNLEVLSLFSNKIEAIEN--IDMLTMLVIISLGNNLIDTVEGIER-------------------- 167
            ..|..||:.:|.:...:.  |:.|:.|..:|..||.|.::.|::|
 Frog   961 TKLRRLSINNNLLAGFDRHVIESLSHLHFLSAENNNISSLAGLQRGYKLIELYLSNNCISSNQEI 1025

  Fly   168 --FRFMNNLKIINLEGNPIAKRTNFCLLKYISAILPKLNYYEYTFIKSELRAEACNLYYREIREI 230
              .:.:|||.|:::.||||       |||:       .||  ..|:...|.|
 Frog  1026 YSLKGLNNLVILDMWGNPI-------LLKH-------ENY--RLFVIFHLSA------------- 1061

  Fly   231 EDKQEKEIQARKFLEREQSEAK--------RLASSFVEHLDGHQLFDSL----WRGDEDGRVLML 283
                   |:|...:..|.||.:        ||.|..:....|||.|..|    ||
 Frog  1062 -------IKALDGVAVEPSECENAKDMFGGRLTSDMIAERIGHQRFTELQDLNWR---------- 1109

  Fly   284 VGTQAQELADEYDKDIFELTQEIYKLGLERFTERDEEIRDF--------FNNLFDGQEELQ-ILG 339
              |.:....|....|.|...|.:   .||     :..:..|        ..||:.....:: ||.
 Frog  1110 --TSSIRSIDLVPADHFRNVQTV---NLE-----NNNLTSFSGLIFLPNIKNLYLNHNRIESILP 1164

  Fly   340 QNEIEWFLQFREIIFEEARIRLLKLEQNSMHGE------DEDTPENLKLSDALDKLNIQF--EDA 396
            |.:.:..|..|:|:.::.        .:|.:|:      ..||.....||..:..|.:..  .:.
 Frog  1165 QQKSQSHLTNRQILHQKV--------SSSGYGQQGTSKGSRDTVYGEALSPVMQSLEVLHLGYNG 1221

  Fly   397 INDLWQALMA-----QELYLH-------ESIQESTINFHRKIAELMSKFVEQSQAFFVQLRE-IT 448
            ||.|....:.     :.|||.       |.::  .:.|.|::....::....::..|.:|.. ::
 Frog  1222 INSLPMLQLGRLRNLKSLYLQGNEISHVEGLE--NLQFLRELVLDHNRIKAIAETSFAKLNSLVS 1284

  Fly   449 LHFSENMTEILTRFISTKFALQDFDDVP--IELRVCVDDRDAILNLIAGMKDYHTLRLDEREDTI 511
            |:..||             .|:|.:::|  ::||          .|:.|......:...|:.:.|
 Frog  1285 LNLEEN-------------RLRDLNNLPPLLKLR----------KLLIGSNKIQEISEIEKLEVI 1326

  Fly   512 AT-----------RTKEFVDNM----------IDQLNSNEVERHRSKILEINFFVEMMTDAMTSL 555
            ..           ..|.|:.|:          :|.:.....:|.|:::    :|:|..:   .::
 Frog  1327 PALVELSISGNPISRKPFLRNLLVVRLQNLQILDGILITAEDRARAEM----YFMEQQS---LTV 1384

  Fly   556 PHDVRD 561
            |:.|.|
 Frog  1385 PNAVMD 1390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ppr-Y	NP_001015502.3	leucine-rich repeat	63..82	CDD:275378	6/18 (33%)
		LRR	<80..313	CDD:443914	68/268 (25%)
		PPP1R42	82..>176	CDD:455733	33/117 (28%)
		leucine-rich repeat	83..104	CDD:275378	5/20 (25%)
		leucine-rich repeat	105..126	CDD:275378	10/20 (50%)
		leucine-rich repeat	127..148	CDD:275378	6/22 (27%)
		leucine-rich repeat	149..162	CDD:275378	5/12 (42%)
lrrc9	XP_017951824.1	PPP1R42	46..243	CDD:455733
		leucine-rich repeat	56..77	CDD:275380
		leucine-rich repeat	78..99	CDD:275380
		leucine-rich repeat	100..121	CDD:275380
		leucine-rich repeat	122..143	CDD:275380
		leucine-rich repeat	144..166	CDD:275380
		LRR	622..1059	CDD:443914	51/178 (29%)
		leucine-rich repeat	703..723	CDD:275380
		leucine-rich repeat	724..745	CDD:275380
		leucine-rich repeat	746..767	CDD:275380
		leucine-rich repeat	768..794	CDD:275380
		leucine-rich repeat	795..821	CDD:275380
		leucine-rich repeat	822..918	CDD:275380	7/21 (33%)
		PPP1R42	892..1074	CDD:455733	56/213 (26%)
		leucine-rich repeat	919..940	CDD:275380	5/20 (25%)
		leucine-rich repeat	941..962	CDD:275380	10/20 (50%)
		leucine-rich repeat	963..986	CDD:275380	6/22 (27%)
		leucine-rich repeat	1009..1033	CDD:275380	0/23 (0%)
		PPP1R42	1103..1369	CDD:455733	53/318 (17%)
		leucine-rich repeat	1127..1148	CDD:275380	4/28 (14%)
		leucine-rich repeat	1149..1174	CDD:275380	6/24 (25%)
		leucine-rich repeat	1175..1211	CDD:275380	8/43 (19%)
		leucine-rich repeat	1212..1235	CDD:275380	4/22 (18%)
		leucine-rich repeat	1236..1257	CDD:275380	4/22 (18%)
		leucine-rich repeat	1258..1281	CDD:275380	3/22 (14%)
		leucine-rich repeat	1282..1305	CDD:275380	6/35 (17%)
		leucine-rich repeat	1306..1328	CDD:275380	4/21 (19%)