Protein Alignment Ppr-Y and Lrriq1

DIOPT Version :10

• Sequence 1: NP_001015502.3
• Gene: Ppr-Y / 3355180
• FlyBaseID: FBgn0046697
• Length: 569
• Species: Drosophila melanogaster
• Sequence 2: XP_011241894.1
• Gene: Lrriq1 / 74978
• MGIID: 1922228
• Length: 1717
• Species: Mus musculus
• Alignment Length: 674
• Identity: 137/674 - (20%)
• Similarity: 235/674 - (34%)
• Gaps: 239/674 - (35%)

  Fly    80 LPNLTKLCLNCNKIETIENIEMLTNLKDLNLSFNFIEKIENLDTLVNLEVLSLFSNKIEAIENID 144
            |.||:.:.||.|.:.:|...:..|||:.|.||.|.|.:|..|::|..|:.|::..|::.:.:.:.
Mouse   873 LENLSVVLLNNNLLTSIHGFDGCTNLQSLELSHNKITRISGLESLKYLQELTVDHNQLISTKGLC 937

  Fly   145 MLTMLVIISLGNNLIDTVEGIERFRFMNNLKIINLEGN----PIAKRTNFCLLKYI--------- 196
            ....:|.:...:|.:..::||..   ...|:||.|:||    |.:.| |..||:.:
Mouse   938 EAPTIVYLDCSHNHLTGIDGIGN---CGLLQIIKLQGNYLREPPSLR-NHVLLRELHLDDNSISS 998

  Fly   197 -----SAILPKLNYYEY------TFIK-----------------SELRAEAC--NLYYREIREI- 230
                 |..||.|.|...      |.:.                 |:|....|  |..| .:||:
Mouse   999 VEGLSSCWLPLLQYLSISQNSLATIVPLFHLVSLEKLDVSNNCLSDLTNVMCWFNACY-SLRELC 1062

  Fly   231 ------------EDKQEKEIQARKFLEREQSEAKRLASSFVEHLDGHQLFDSLWRGDEDGRVLM- 282
                        .|...|.:.|.:.|..:.     |.|...:.::.|.        .:|.|.|:
Mouse  1063 LTGNPVLQEINWRDSILKTLPALRVLNGDM-----LNSYANDRIEEHY--------HQDLRCLLA 1114

  Fly   283 LVGTQAQEL----------------------ADEYDKDIFELTQE---IYKLGLERFTER----- 317
            |...|.||.                      ..:|.||:.:|:.|   .::.|....|||
Mouse  1115 LCQYQLQEFNLLPEKYITQKRDILTLHAVDRLSQYYKDLMKLSHECRRAHEQGDVNTTERSAAET 1179

  Fly   318 DEEIRDFFN--------------------------NLFDGQ--------EELQILGQNEIEWFLQ 348
            ::...||.|                          |..|..        |||:  |:|: |..:.
Mouse  1180 NKNHPDFSNTDSALQNKTLHAQTNSCEADSPATSPNPLDTVFRPSTSHCEELR--GRNQ-EKLMA 1241

  Fly   349 FREIIFEEARIRL----------LKLEQNSM---HGEDEDTPENLKLSDALDKLNIQFEDAINDL 400
            .:.   |::||..          :|:..:.|   |..:..:|....:             .|...
Mouse  1242 HKS---EQSRISSRSNSRASFIEMKMADSPMSNHHNAERSSPTKAAM-------------VIQAQ 1290

  Fly   401 WQALMAQ-----ELYLH----ESIQESTINFHRKIAELMSK----FVEQSQAFFVQLREITLHFS 452
            |::.:|.     ...:|    |.:|:..||......|...|    ..||.:...:.::.:...|
Mouse  1291 WRSYIAHRQINCSAEMHPTTTEPLQDPLINNQTTSNEERRKTNMDIQEQREKAALHIQAVWKGF- 1354

  Fly   453 ENMTEILTRFIST-KFALQD------FDDVPIELRVCVD---DRDA------------------- 488
                 ||.:.::| :.|::|      ::::.:|     |   |.||
Mouse  1355 -----ILRKKLATARKAIKDEESGEEYEEIDLE-----DFEFDEDALEKDWPALDSTGFPSQTLP 1409

  Fly   489 ILNLIAGMKDYHTLRLDEREDTIATR-TKEFVDNMIDQLNSNEV-----ERHRSKILEINFFVEM 547
            :.|.:...|:..|||.||...||..| .:.::.|..:.:.|:|.     .|..|.||      ..
Mouse  1410 LSNQLPWPKNSRTLRHDETSPTIPVRPAQAWLCNEKENVMSSEYTQLSSSRSESGIL------SW 1468

  Fly   548 MTDAMTS---LPHDVRDELIAEDY 568
            ..|:.||   |....::|.|:|::
Mouse  1469 TPDSKTSRKNLLQSEKEEKISEEW 1492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ppr-Y	NP_001015502.3	leucine-rich repeat	63..82	CDD:275378	1/1 (100%)
		LRR	<80..313	CDD:443914	69/314 (22%)
		PPP1R42	82..>176	CDD:455733	25/93 (27%)
		leucine-rich repeat	83..104	CDD:275378	5/20 (25%)
		leucine-rich repeat	105..126	CDD:275378	9/20 (45%)
		leucine-rich repeat	127..148	CDD:275378	3/20 (15%)
		leucine-rich repeat	149..162	CDD:275378	2/12 (17%)
Lrriq1	XP_011241894.1	PTZ00121	<173..657	CDD:173412
		leucine-rich repeat	833..854	CDD:275380
		PPP1R42	836..1090	CDD:455733	53/221 (24%)
		leucine-rich repeat	855..875	CDD:275380	1/1 (100%)
		leucine-rich repeat	876..897	CDD:275380	5/20 (25%)
		leucine-rich repeat	898..919	CDD:275380	9/20 (45%)
		leucine-rich repeat	920..941	CDD:275380	3/20 (15%)
		leucine-rich repeat	942..963	CDD:275380	4/23 (17%)
		leucine-rich repeat	964..982	CDD:275380	8/18 (44%)
		leucine-rich repeat	986..1009	CDD:275380	3/22 (14%)
		leucine-rich repeat	1010..1031	CDD:275380	3/20 (15%)
		leucine-rich repeat	1058..1084	CDD:275380	4/25 (16%)
		IQCD	1337..1365	CDD:467745	6/33 (18%)