Protein Alignment Ppr-Y and Ppp1r42

DIOPT Version :10

• Sequence 1: NP_001015502.3
• Gene: Ppr-Y / 3355180
• FlyBaseID: FBgn0046697
• Length: 569
• Species: Drosophila melanogaster
• Sequence 2: NP_663730.1
• Gene: Ppp1r42 / 69312
• MGIID: 1921138
• Length: 357
• Species: Mus musculus
• Alignment Length: 333
• Identity: 72/333 - (21%)
• Similarity: 128/333 - (38%)
• Gaps: 95/333 - (28%)

  Fly    58 LEQILTMRLEFNNILRIDHLWILPNLTKLCLNCNKIETIENIEMLTNLKDLNLSFNFIEKIENLD 122
            |::|..:.....||..||.|.:..||:.|.|..|:|..:.|:...|||..|.|..|.|..||||.
Mouse    27 LKKITHINFSDRNIDSIDDLSLCRNLSVLYLYDNRISQVTNLNYTTNLTHLYLQNNCISCIENLS 91

  Fly   123 TLVNLEVLSLFSNKIEAIENID------------------------------MLTMLVIISLGNN 157
            :|..||.|.|..|.|..||.::                              :...|..:::.||
Mouse    92 SLKKLEKLYLGGNYIAVIEGLEGLEELRELHVESQRLPLGEKLLFDPRTLRSLAKSLSTLNISNN 156

  Fly   158 LIDTVEGIERFRFMNNLKII-----------------------NLEGNPIAKRTNFCLLKYISAI 199
            .||.::.:|....:|:|..:                       :|.|||:      ||
Mouse   157 NIDDIKDLEILENLNHLIAVDNQLMHVKDLELLLKKLMKLWKMDLNGNPV------CL------- 208

  Fly   200 LPKLNYYEYTFIKSELRAEACNLYYREIREIEDKQEKEI-------QARKFLEREQSEAKRLASS 257
              |..|.:...:.|:      :|.:.:.:||:|.:.:.:       .|:|..::.:|.::..::|
Mouse   209 --KPKYRDKLILTSK------SLEFLDGKEIKDMERQFLMNWKASKDAKKISKKRRSRSEDASNS 265

  Fly   258 FVEHLDG-HQLFDSLWRGDEDGRVLM-------LVGTQAQELADEYDKDIFELTQEIYKLGLER- 313
            ::.:.:. |.:....:......:|:.       ||...|.....:.||.  .:|::|..|.|:.
Mouse   266 YISNFETVHHIVPVYYPQVGKPKVIFFSDVQRYLVHGNASSKCSQEDKT--TITEDIGNLSLKES 328

  Fly   314 ---FTERD 318
               .|:.|
Mouse   329 ESSLTKND 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ppr-Y	NP_001015502.3	leucine-rich repeat	63..82	CDD:275378	5/18 (28%)
		LRR	<80..313	CDD:443914	63/300 (21%)
		PPP1R42	82..>176	CDD:455733	35/123 (28%)
		leucine-rich repeat	83..104	CDD:275378	6/20 (30%)
		leucine-rich repeat	105..126	CDD:275378	10/20 (50%)
		leucine-rich repeat	127..148	CDD:275378	8/50 (16%)
		leucine-rich repeat	149..162	CDD:275378	5/12 (42%)
Ppp1r42	NP_663730.1	PPP1R42	27..246	CDD:411060	55/239 (23%)
		LRR 1	29..50		6/20 (30%)
		leucine-rich repeat	31..51	CDD:275380	5/19 (26%)
		LRR 2	51..72		7/20 (35%)
		LRR 3	73..94		10/20 (50%)
		leucine-rich repeat	74..95	CDD:275380	10/20 (50%)
		LRR 4	95..116		8/20 (40%)
		leucine-rich repeat	96..147	CDD:275380	8/50 (16%)
		LRR 5	117..138		0/20 (0%)
		LRR 6	147..168		6/20 (30%)
		leucine-rich repeat	148..169	CDD:275380	6/20 (30%)
		LRR 7	169..190		2/20 (10%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	329..357		2/8 (25%)