Protein Alignment Ppr-Y and Ppp1r42

DIOPT Version :10

• Sequence 1: NP_001015502.3
• Gene: Ppr-Y / 3355180
• FlyBaseID: FBgn0046697
• Length: 569
• Species: Drosophila melanogaster
• Sequence 2: NP_001121041.1
• Gene: Ppp1r42 / 683514
• RGDID: 1585679
• Length: 355
• Species: Rattus norvegicus
• Alignment Length: 322
• Identity: 69/322 - (21%)
• Similarity: 123/322 - (38%)
• Gaps: 91/322 - (28%)

  Fly    58 LEQILTMRLEFNNILRIDHLWILPNLTKLCLNCNKIETIENIEMLTNLKDLNLSFNFIEKIENLD 122
            |::|..:.....||..||.|.:..||:.|.|..|:|..:.|:...|||..|.|..|.|..||||.
  Rat    27 LKKITHINFSDRNIDSIDDLSLCKNLSVLYLYDNRISQVTNLNYTTNLTHLYLQNNCISCIENLS 91

  Fly   123 TLVNLEVLSLFSNKIEAIENID------------------------------MLTMLVIISLGNN 157
            :|..||.|.|..|.|..:|.::                              :...|..:::.||
  Rat    92 SLKKLEKLYLGGNYIAVVEGLEGLEELRELHVESQRLPLGEKLLFDPRTLRSLAKSLSTLNISNN 156

  Fly   158 LIDTVEGIERFRFMNNLKII-----------------------NLEGNPIAKRTNFCLL-KYISA 198
            .||.::.:|....:|:|..:                       :|.|||:      ||. ||...
  Rat   157 NIDDIKDLEMLENLNHLIAVDNQLMHVKDLEVLLRKLMKLWKMDLNGNPV------CLKPKYRDR 215

  Fly   199 ILPKLNYYEYTFIKSELRAEACNLYYREIREIED------KQEKEIQARKFLEREQSEAKRLASS 257
            ::......|:             |..:||:.:|.      |..||  |:|..::.::.::...:|
  Rat   216 LILMSKSLEF-------------LDGKEIKNLERQFLMNWKASKE--AKKISKKRRNRSEDQNNS 265

  Fly   258 FVEHLDG-HQLFDSLWRGDEDGRVLML------VGTQAQELADEYDKDIFELTQEIYKLGLE 312
            ::.:.:. |.:....:......:|:..      :|..:.:.:.|   |...:|::|..|.|:
  Rat   266 YISNFETIHHIVPVYYPQVGKPKVVFFSDVQRYLGKASSKFSQE---DKTTITEDIGNLSLK 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ppr-Y	NP_001015502.3	leucine-rich repeat	63..82	CDD:275378	5/18 (28%)
		LRR	<80..313	CDD:443914	62/300 (21%)
		PPP1R42	82..>176	CDD:455733	34/123 (28%)
		leucine-rich repeat	83..104	CDD:275378	6/20 (30%)
		leucine-rich repeat	105..126	CDD:275378	10/20 (50%)
		leucine-rich repeat	127..148	CDD:275378	7/50 (14%)
		leucine-rich repeat	149..162	CDD:275378	5/12 (42%)
Ppp1r42	NP_001121041.1	PPP1R42	27..246	CDD:411060	55/237 (23%)
		leucine-rich repeat	30..51	CDD:275380	6/20 (30%)
		leucine-rich repeat	74..95	CDD:275380	10/20 (50%)
		leucine-rich repeat	96..147	CDD:275380	7/50 (14%)
		leucine-rich repeat	148..169	CDD:275380	6/20 (30%)
		leucine-rich repeat	170..195	CDD:275380	2/24 (8%)