DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ppr-Y and lrguk

DIOPT Version :10

Sequence 1:NP_001015502.3 Gene:Ppr-Y / 3355180 FlyBaseID:FBgn0046697 Length:569 Species:Drosophila melanogaster
Sequence 2:XP_068076856.1 Gene:lrguk / 559670 ZFINID:ZDB-GENE-050419-232 Length:739 Species:Danio rerio


Alignment Length:437 Identity:103/437 - (23%)
Similarity:178/437 - (40%) Gaps:72/437 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    39 LKHVHRGEGRRLHQLEPVVLEQILTMRLEFNNILRIDHLWILPNLTKLCLNCNKIETIENIEMLT 103
            ||.|:....:.....:......:..:.|:.|:...|..|.....|:.|.|..|.|..|..::.|.
Zfish   105 LKEVNFSHNQMTAMKDLSAYSSLTKLILDHNSFSVIRGLEKCKRLSHLSLAHNNISRIRGLDHLP 169

  Fly   104 NLKDLNLSFNFIEKIENLDTLVNLEVLSLFSNKIEAIENIDMLTMLVIISLGNNLIDTVEGIERF 168
             |::|.|:.|.|.|||||.||.||:||.|..|:|:::..:..|..|..::|.:|||..::.....
Zfish   170 -LRELCLAGNMINKIENLQTLHNLQVLDLSCNRIQSLTGLQNLRFLGTVNLESNLITEIKEAAHL 233

  Fly   169 RFMNNLKIINLEGNPIAKRTNFCLLKYISAILPKLNYYEYTFIKSELRAEACNLYYREIREIEDK 233
            ..:..|:.|||..||:....::.:.  :..:|..|...:...:.:|.:..|.|.|        |.
Zfish   234 HDLILLREINLLKNPVQDHDDYRIA--VIFLLQHLILLDKQTVTAEEKVAAVNKY--------DP 288

  Fly   234 QEKEIQARKFLEREQSEAKRLASSFVEHLDGHQ-LFDS-LWRGDEDGRVLMLVGTQA-------- 288
            ..:.:.||..:           :..|..|...| :||| |...|....:|:|.|.||        
Zfish   289 PLEVVAARDHM-----------THLVYQLMQPQVIFDSTLPSLDAPYPMLVLTGPQACGKRELAH 342

  Fly   289 ---QELADEYDKDIFELTQEIY---KLGLERFTERDEEIRDFFNNLFDGQEELQILGQNEIEWFL 347
               ||.:|.:.......|:..|   :.||:.....:||    |:|:....:.:|.: |....|:.
Zfish   343 KLCQEFSDYFAYGACHTTRGPYFGEEDGLDYHFVTEEE----FHNMIQMGQFIQTM-QYGGHWYG 402

  Fly   348 QFREIIFEEARIRL-----LKLE-----QNSMHGEDEDTPENLKLSDALDKL-----------NI 391
            ..||.|...||..|     ::||     :||..    :....|.:...:|..           |.
Zfish   403 LSRESIERVAREGLACCVHMELEGVFSLKNSYF----EPRYVLLIPSVVDNYVLFLKARGFYSNA 463

  Fly   392 QFEDAIN--DLWQALMAQELYLHESI--QESTINFHRKIAELMSKFV 434
            |.|.|::  ||:..:..:.....:||  .:.....:|.:.:|:.:::
Zfish   464 QMETAVSRIDLYARINRERPGFFDSIIPCDDRAEAYRSLKQLVKEYL 510

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ppr-YNP_001015502.3 leucine-rich repeat 63..82 CDD:275378 4/18 (22%)
LRR <80..313 CDD:443914 67/248 (27%)
PPP1R42 82..>176 CDD:455733 33/93 (35%)
leucine-rich repeat 83..104 CDD:275378 7/20 (35%)
leucine-rich repeat 105..126 CDD:275378 12/20 (60%)
leucine-rich repeat 127..148 CDD:275378 7/20 (35%)
leucine-rich repeat 149..162 CDD:275378 5/12 (42%)
lrgukXP_068076856.1 PPP1R42 <61..118 CDD:455733 3/12 (25%)
leucine-rich repeat 61..82 CDD:275380
leucine-rich repeat 83..104 CDD:275380
leucine-rich repeat 105..126 CDD:275380 3/20 (15%)
PPP1R42 108..279 CDD:455733 46/173 (27%)
leucine-rich repeat 127..148 CDD:275380 4/20 (20%)
leucine-rich repeat 149..168 CDD:275380 6/18 (33%)
leucine-rich repeat 170..191 CDD:275380 12/20 (60%)
leucine-rich repeat 192..210 CDD:275380 6/17 (35%)
leucine-rich repeat 211..238 CDD:275380 6/26 (23%)
GMPK 326..449 CDD:238026 30/131 (23%)
PHA03307 520..>739 CDD:223039
Blue background indicates that the domain is not in the aligned region.

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