DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ppr-Y and lrrc61

DIOPT Version :9

Sequence 1:	NP_001015502.3	Gene:	Ppr-Y / 3355180	FlyBaseID:	FBgn0046697	Length:	569	Species:	Drosophila melanogaster
Sequence 2:	NP_001036219.1	Gene:	lrrc61 / 553439	ZFINID:	ZDB-GENE-060616-245	Length:	260	Species:	Danio rerio

Alignment Length:	286	Identity:	64/286 - (22%)
Similarity:	110/286 - (38%)	Gaps:	67/286 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 SLIESSYLKHVHRGEGRRLHQLEPVVLEQILTMRLEFNNILRIDHLWILPNLTKLCLNCNKIETI 96
            |.|.:..||. |.||         ..||.||.::|:...|..:..:....||.:|.|:.|.|..:
Zfish    13 SKITTMLLKS-HTGE---------FDLESILFLKLKNLGIYDLGCIGECINLERLDLSGNNITNL 67

  Fly    97 ENIEMLTNLKDLNLSFNFIEKIENLDTLVNLEVLSLFSNKIEAIENIDMLTMLVIISLGNNLIDT 161
            ..:..|..|..||||.|.|..:|.|.|..:|:.|::..|.|.:::|:..|..|
Zfish    68 GPLSPLRRLLSLNLSANRISNLEPLATCESLQSLNVAGNVISSVDNLHSLKSL------------ 120

  Fly   162 VEGIERFRFMNNLKIINLEGNPIAKRTNFCLLKYISAILPKLNYYEYTFI---KSELRAEACNLY 223
             ..:|..|..:|.....   ||:.|..::..|  |..|.|.:...:...:   .|:|
Zfish   121 -RRLENIRLKDNTYNFT---NPVCKNPSYRPL--ILEIFPNMKVLDGERVVGRGSDL-------- 171

  Fly   224 YREIREIEDKQEKEIQARKFLEREQSEAKRLASSFVEHLDGHQLFDSLWRGDEDGRVLM------ 282
            |:..::|:|    .|:|..:...:..|. |....:|:        ||.|........::
Zfish   172 YQLCKDIDD----SIKAGMYKNGQLLEV-RETEPWVD--------DSFWEIKRSNNAIVDEAYKQ 223

  Fly   283 ---------LVGTQAQELADEYDKDI 299
                     |:.::|..|..:.:::|
Zfish   224 FSDVLHECRLLNSRAGHLISQNERNI 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ppr-Y	NP_001015502.3	leucine-rich repeat	63..82	CDD:275378	2/18 (11%)
		LRR_8	81..137	CDD:290566	20/55 (36%)
		LRR_4	81..121	CDD:289563	15/39 (38%)
		leucine-rich repeat	83..104	CDD:275378	6/20 (30%)
		LRR_4	103..143	CDD:289563	14/39 (36%)
		leucine-rich repeat	105..126	CDD:275378	10/20 (50%)
		LRR_8	126..184	CDD:290566	11/57 (19%)
		LRR_4	126..166	CDD:289563	7/39 (18%)
		leucine-rich repeat	127..148	CDD:275378	6/20 (30%)
		leucine-rich repeat	149..162	CDD:275378	1/12 (8%)
lrrc61	NP_001036219.1	leucine-rich repeat	54..81	CDD:275378	8/26 (31%)
lrrc61	NP_001036219.1	leucine-rich repeat	98..122	CDD:275378	7/36 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579426
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840