DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ppr-Y and Lrrc43

DIOPT Version :10

Sequence 1:NP_001015502.3 Gene:Ppr-Y / 3355180 FlyBaseID:FBgn0046697 Length:569 Species:Drosophila melanogaster
Sequence 2:NP_001028633.1 Gene:Lrrc43 / 381741 MGIID:2685907 Length:667 Species:Mus musculus


Alignment Length:444 Identity:97/444 - (21%)
Similarity:163/444 - (36%) Gaps:116/444 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    14 PLVDEVIYPDIEP-----GIINRSLIESSYLKHVHRGEGRRLHQL---EPVVLEQILTMRLEFNN 70
            |..:|.:.|:.|.     |::..:....:.||.. ..|.|.|.:|   .|::::.  |....:..
Mouse    66 PKEEETLVPEEETVEALLGLVRSNHSPWAMLKDA-SAEDRFLRELAIQNPLMIKD--TFFYSYFR 127

  Fly    71 ILRI----------DHLWILPNLTKLCLNCNKIETIENIEMLTNLKDLNLSFNFIEKIENLDTL- 124
            .||:          |.|..| .|.:|.|:.||||.|:...:...||.|.|..|.|..:|.|.:. 
Mouse   128 SLRVVNKGVSLVDKDLLKFL-KLEELVLSANKIEEIDANNLPPTLKVLELYGNLIASMECLCSAP 191

  Fly   125 -VNLEVLSLFSNK-IEAIENIDMLT----MLVIISLG-NNLIDTVEGIERFRFMNNLKIINLEGN 182
             ..|:.|.|..|| :..:|::.:.:    .||.:.|| |||.|....|.....:.:|:::.|:||
Mouse   192 PPRLQHLGLGHNKLLGPLESLYVTSHNWPQLVSLDLGFNNLTDLQNMILGLSTLRHLRLLVLQGN 256

  Fly   183 PIA-----------KRTNFCLLKYISAILPKLNYYEYTFIKSELRAEACNLYYR--EIREIEDKQ 234
            |::           ...:.|:|..|:....:.:.:....|..:|.|........  .:|.:.|. 
Mouse   257 PLSLVPYYRGFTIDSLAHLCVLDDITVSPNEKHQFRGLNIHGDLLAREAQFVVTIGNVRGVLDS- 320

  Fly   235 EKEIQARKFLEREQ-------SEAKRLASSFVEHLDGHQLFDSLWRGDED--GRVLMLV-GTQAQ 289
                   ..|:.|.       |.:..:...|||              |||  ..|..|| .|...
Mouse   321 -------SILDPEPGPDGPFISYSYYVTYDFVE--------------DEDMERNVSGLVEATHHD 364

  Fly   290 ELADEYDKDIFELTQEIYK----------LGLERF-----TERDEEIRDF----FNNLFDGQEEL 335
            .:.||.||......:|..:          .|.:||     .|..:|:.:|    .:.:.:|..| 
Mouse   365 SVLDEIDKHFSGTDEEDQQEDPLDGRHRHRGRQRFHPGSTEEMSKELSEFIAKEMSQMAEGSVE- 428

  Fly   336 QILGQNEIEWFLQFREIIFEEARIRLLKLEQNSMHGEDEDTPENLKLSDALDKL 389
              .|..|::|                   .:.|:.......|:::..|:.|.||
Mouse   429 --SGITEVDW-------------------SETSISIHSAPLPQSIDSSEELAKL 461

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ppr-YNP_001015502.3 leucine-rich repeat 63..82 CDD:275378 6/28 (21%)
LRR <80..313 CDD:443914 64/273 (23%)
PPP1R42 82..>176 CDD:455733 32/101 (32%)
leucine-rich repeat 83..104 CDD:275378 8/20 (40%)
leucine-rich repeat 105..126 CDD:275378 8/22 (36%)
leucine-rich repeat 127..148 CDD:275378 6/25 (24%)
leucine-rich repeat 149..162 CDD:275378 8/13 (62%)
Lrrc43NP_001028633.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..24
LRR 1 148..169 8/20 (40%)
PPP1R42 154..291 CDD:455733 37/136 (27%)
LRR 2 170..191 8/20 (40%)
leucine-rich repeat 171..194 CDD:275378 8/22 (36%)
LRR 3 194..213 6/18 (33%)
leucine-rich repeat 195..221 CDD:275378 6/25 (24%)
LRR 4 221..242 9/20 (45%)
leucine-rich repeat 222..247 CDD:275378 9/24 (38%)
leucine-rich repeat 248..259 CDD:275378 5/10 (50%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 374..407 4/32 (13%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 533..570
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 616..640
Blue background indicates that the domain is not in the aligned region.

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