Protein Alignment Ppr-Y and dtr

DIOPT Version :10

• Sequence 1: NP_001015502.3
• Gene: Ppr-Y / 3355180
• FlyBaseID: FBgn0046697
• Length: 569
• Species: Drosophila melanogaster
• Sequence 2: NP_724335.2
• Gene: dtr / 318856
• FlyBaseID: FBgn0023090
• Length: 1483
• Species: Drosophila melanogaster
• Alignment Length: 721
• Identity: 151/721 - (20%)
• Similarity: 254/721 - (35%)
• Gaps: 251/721 - (34%)

  Fly    39 LKHVHRGEGRRLHQLEPVVLEQIL-------TMRLEFNNILR--------IDHLWILPNLTKLCL 88
            :.:.:|.|...|:::.|..|:::.       |.||  |::|.        |:.|.....|..|.|
  Fly     1 MSNSNRKEITGLNRMTPKGLKELCKKDKLYQTPRL--NDVLYLHYQGFQCIESLEEYTELKCLWL 63

  Fly    89 NCNKIETIENIEMLTNLKDLNLSFNFIEKIENLDTLVNLEVLSLFSNKIEAIENI--------DM 145
            .||.|..|:.:|.|:.||.|.|..|.|.||||||....|:.|:|.||.|..|:||        :.
  Fly    64 ECNAISEIQGLEKLSKLKCLFLQNNLITKIENLDPCRELDTLNLSSNHIRKIQNIGTNVLPVLNT 128

  Fly   146 LTM-------------------LVIISLGNNLIDTVEGIERFRFMNNLKIINLEGNPIAKRTNFC 191
            ||:                   |.::.|.||.||.:..::.|..|.|||::.|:|||:..|
  Fly   129 LTISSNYLKDSESLSDLIQCKTLSVLDLSNNRIDDILIVKIFEQMLNLKVLVLQGNPVVSR---- 189

  Fly   192 LLKYISAIL---PKLNYYEY--TFIKSELRAEA-----------------------------CNL 222
            |.:|...::   .:|.|.:.  .|.:....|||                             |.:
  Fly   190 LPQYRKTLILACKELTYLDSRPVFPRDRACAEAWKRDGYEGERKENNRWNRAERRKTRESINCTI 254

  Fly   223 YYREIREIEDKQEKEIQ------------ARKFL----------------EREQSEAKRLASSFV 259
            ..|......|:|:..::            |||.:                |:..||....:||.:
  Fly   255 RMRNSHRPPDQQDPLLRSSDSEDDTCAETARKKVALENGCVDDLWEEVSGEQPISEDGTNSSSSL 319

  Fly   260 EHLDGHQLFDSLW------RGDEDGRVLMLVGTQAQEL-ADEYDKDIFE-----------LTQEI 306
            |..||....|.|.      |...:||..:|..|:...: :...|.:|||           ..:.:
  Fly   320 EDNDGTSSQDDLIAEKLSNRRTLEGRPTVLYETEVSNVKSANNDINIFEEGVGKASQIIIEDKPV 384

  Fly   307 YKLGL-----------------------ERFTERDEEIRDF-----FNNLFDGQEELQILGQNEI 343
            .|:.|                       |...:.|.||::.     ..||....|::.
  Fly   385 TKIKLINEPSCMNDKSAMNCTSMGPVVKENDFDEDAEIKNVDDMVPCQNLIKSNEDIN------- 442

  Fly   344 EWFLQFREIIFEEARIRLLKLEQN--------SMHGEDEDTPENLKLSDALDKLNIQFEDAINDL 400
                  .|..|..      ||:|:        ....|.::..|.|.:.::..|       ..|::
  Fly   443 ------SEFGFSS------KLKQDFDQTCTALRNDAECKEFDEELTIKESESK-------PFNEM 488

  Fly   401 WQALMAQELYLHE----SIQESTINFHRKIAELMSKFVEQSQAFFVQLREITLHFSEN-MTEILT 460
            :....|::..|:|    ::.|:|...|          |..:  ||.:..::...:.|: |..:|.
  Fly   489 YDIFAAEDDKLNETLDLNLNETTCPHH----------VHDN--FFSEQNKMPSFYEEDIMINLLP 541

  Fly   461 RFISTKFALQDFDDVPIELRVCVDD---------------RDAILNLIAGMKDYHTLRLD---ER 507
            :  :.:..|.:.|.: ||...|..|               |.:..||| |:....|.|.|   :.
  Fly   542 K--TKEKTLLEKDSI-IENEKCAHDLDEMGRQMEEDLAELRQSTQNLI-GISIDETARTDSETDE 602

  Fly   508 EDTIATR-------TKEFVDNMIDQLNSNEVERHRSKILEIN---------------FFVEMMTD 550
            ||.||.:       .::|.|..:..:.:.|.:.....:.:.|               .|.:::.|
  Fly   603 EDLIAQQDPYSPLLKQQFKDRRMKIMLTEETKAQEESLSDRNIALSNESDQDDKQDQLFAKILDD 667

  Fly   551 AMTSLP 556
            |..::|
  Fly   668 ATENIP 673

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ppr-Y	NP_001015502.3	leucine-rich repeat	63..82	CDD:275378	7/26 (27%)
		LRR	<80..313	CDD:443914	84/362 (23%)
		PPP1R42	82..>176	CDD:455733	42/120 (35%)
		leucine-rich repeat	83..104	CDD:275378	9/20 (45%)
		leucine-rich repeat	105..126	CDD:275378	12/20 (60%)
		leucine-rich repeat	127..148	CDD:275378	10/28 (36%)
		leucine-rich repeat	149..162	CDD:275378	6/12 (50%)
dtr	NP_724335.2	leucine-rich repeat	38..57	CDD:275380	3/18 (17%)
		PPP1R42	39..225	CDD:455733	59/189 (31%)
		leucine-rich repeat	58..79	CDD:275380	9/20 (45%)
		leucine-rich repeat	80..101	CDD:275380	12/20 (60%)
		leucine-rich repeat	102..125	CDD:275380	9/22 (41%)
		leucine-rich repeat	126..147	CDD:275380	2/20 (10%)
		leucine-rich repeat	151..175	CDD:275380	8/23 (35%)