DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ppr-Y and Lrrc23

DIOPT Version :9

Sequence 1:	NP_001015502.3	Gene:	Ppr-Y / 3355180	FlyBaseID:	FBgn0046697	Length:	569	Species:	Drosophila melanogaster
Sequence 2:	NP_001381276.1	Gene:	Lrrc23 / 312707	RGDID:	1304779	Length:	345	Species:	Rattus norvegicus

Alignment Length:	250	Identity:	67/250 - (26%)
Similarity:	122/250 - (48%)	Gaps:	44/250 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 NNSEVQKPLVDEVIYPDIEPGIINRSLIESSYLKHVHRG----EGRRLHQLEPVVLEQILTMRLE 67
            :.::::...::|:.|..|.....|: :.::..:.|...|    :|.|:||:..:..|:
  Rat   123 DGNQLRSARLNELPYLQIASFSYNQ-ITDTEGIIHPRLGSLDLKGNRIHQVTGLDPER------- 179

  Fly    68 FNNILRIDHLWILPNLTKLCLNCNKIETIENIEMLTNLKDLNLSFNFIEKIENLDTLVNLEVLSL 132
                        |.||..|.|..|::||...|. |..||:|.|:.|.::|:|.|:.|.||..|.|
  Rat   180 ------------LTNLHTLELRANQLETTIGIN-LPKLKNLYLAQNLLKKVEGLENLSNLTTLHL 231

  Fly   133 FSNKIEAIENIDM-LTMLVIISLGNNLIDTVEGIERFRFMNNLKIINLEGNPIAKRTNF---CLL 193
            ..|:||.::.... :..|..::|.:|:|..:..:.:.|.:..|:.:.|..||.|..|::   .|:
  Rat   232 RDNQIETLDGFSKEMKSLQYLNLRSNMISDLGELAKLRDLPKLRALVLLDNPCADETDYRQEALV 296

  Fly   194 KYISAILPKLN--YYEYTFIKSELRAEACNLYYREIRE-IEDKQEKEIQARKFLE 245
            :  .|.|.:|:  |||     .|.||||     .|||: ::::||:|:...:.:|
  Rat   297 Q--MAHLERLDKEYYE-----DEDRAEA-----EEIRQRLKEEQEQELDPDQDME 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ppr-Y	NP_001015502.3	leucine-rich repeat	63..82	CDD:275378	1/18 (6%)
		LRR_8	81..137	CDD:290566	23/55 (42%)
		LRR_4	81..121	CDD:289563	16/39 (41%)
		leucine-rich repeat	83..104	CDD:275378	8/20 (40%)
		LRR_4	103..143	CDD:289563	16/39 (41%)
		leucine-rich repeat	105..126	CDD:275378	9/20 (45%)
		LRR_8	126..184	CDD:290566	15/58 (26%)
		LRR_4	126..166	CDD:289563	11/40 (28%)
		leucine-rich repeat	127..148	CDD:275378	6/21 (29%)
		leucine-rich repeat	149..162	CDD:275378	4/12 (33%)
Lrrc23	NP_001381276.1	leucine-rich repeat	75..94	CDD:275380
		PPP1R42	80..306	CDD:411060	52/205 (25%)
		leucine-rich repeat	95..116	CDD:275380
		leucine-rich repeat	117..137	CDD:275380	1/13 (8%)
		leucine-rich repeat	138..158	CDD:275380	3/20 (15%)
		leucine-rich repeat	159..182	CDD:275380	7/41 (17%)
		leucine-rich repeat	183..203	CDD:275380	8/20 (40%)
		leucine-rich repeat	204..225	CDD:275380	9/20 (45%)
		leucine-rich repeat	226..248	CDD:275380	6/21 (29%)
		leucine-rich repeat	249..273	CDD:275380	5/23 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339659
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840