DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ppr-Y and Lrrc49

DIOPT Version :10

Sequence 1:NP_001015502.3 Gene:Ppr-Y / 3355180 FlyBaseID:FBgn0046697 Length:569 Species:Drosophila melanogaster
Sequence 2:NP_001423387.1 Gene:Lrrc49 / 300763 RGDID:1309466 Length:752 Species:Rattus norvegicus


Alignment Length:618 Identity:125/618 - (20%)
Similarity:220/618 - (35%) Gaps:212/618 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly    59 EQILTMRLEFNNILRIDHLWILPNLTKLCLNCNKIETIENIEMLTNLKDLNLSFNFIEKIENLDT 123
            |.:..:..:.|.|.||.::..|..|..|.|..|:||.|..:..|.:|:.|.|..|.|:||.||:.
  Rat   178 EHLRLLNFQHNFITRIQNISNLQRLIFLDLYDNQIEEISGLSTLKSLRVLLLGKNRIKKISNLEN 242

  Fly   124 LVNLEVLSLFSNKIEAIENIDMLTMLVIISLGNNL---IDTVEGIERFRFMN------------- 172
            |.||:||.|..|:|..|||::.|..|.:::|..||   :|.:.|::....:|             
  Rat   243 LKNLDVLDLHGNQITKIENVNHLCDLRVLNLARNLLSHVDNLNGLDSLTELNLRHNQITFVRDVD 307

  Fly   173 ----------------------------NLKIINLEGNPIAKRTNFCLLKYISAILPKLNYYEYT 209
                                        :|..|..:|||||:.                ::|::|
  Rat   308 NLPCLQRLFLSFNNITSFESVSCLAESTSLSDITFDGNPIAQE----------------SWYKHT 356

  Fly   210 FIKSELRAEACNLYYREIREIEDKQEKEIQARKFLEREQ--------SEAKRLASSFVE------ 260
            .:::.::....::  :.|.| |:::...:.|:|..|:::        .|.|||..:.|.      
  Rat   357 VLQNMMQLRQLDM--KRITE-EERRVASVVAKKEEEKKRESHKQSLLKEKKRLTINNVARKWDLQ 418

  Fly   261 -----------------------HLDGHQL-------------FDSLWRG---------DEDGRV 280
                                   .:||..:             ..|..:|         :.||..
  Rat   419 QRVANIAIIQDRKDSESPPQESCQIDGGTISAFPEEAGSLDAGLSSALQGLSVTETHLVELDGET 483

  Fly   281 LMLVGTQAQELAD-------------------EYDKDIFELTQEIYKLGLE-------RFTERDE 319
            |.|.|:.|.|..|                   |:|    |:.|.:.||.::       :|.|.:.
  Rat   484 LSLYGSGALECLDRNWSVQTAGMVTTVSFTFIEFD----EIVQVLPKLKMKFPNSLHLKFRETNL 544

  Fly   320 EIRDFFNNLFDGQEELQILGQNEIE-------------WFLQFREIIFEEARIRLLKLEQNSM-- 369
            .:...||.|    .:|:.:.|..|:             :::.||...|...:|...::.||.|  
  Rat   545 VMLQQFNAL----AQLRRVDQLTIDPQGNPVVNFTLWKYYVLFRLSHFSMQKINGTEVTQNDMIM 605

  Fly   370 ---------HGEDEDTPENLKLSDALDKLNIQFEDAIND-------LWQALMAQELYLHESIQES 418
                     |....:.|:...:|...|....||...:.:       |.:.....:..:.|:...:
  Rat   606 AERLFGILAHVASSELPQYRMISILGDARKKQFRYLLENKCKKPGILCEETSDSKRLMGENTNRA 670

  Fly   419 TIN------FHRKIAELMSKFVEQSQAFFVQLREITLHFSENMTEILTRFISTKFALQD-FDDVP 476
            |:|      :|.|:.|:..|            ::....:.|::.:..|.......|||. :..:.
  Rat   671 TLNYTTREFYHEKLEEIKDK------------KKFCRLYVEDLVKEATAINMKNEALQKLWPQMF 723

  Fly   477 IELRVCVDDRDAILNLIAGMKDYHTLRLDERED 509
            |||     .|||::. |.....|..|.|.:..|
  Rat   724 IEL-----VRDAVIE-IRSKDSYMKLCLQQITD 750

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ppr-YNP_001015502.3 leucine-rich repeat 63..82 CDD:275378 5/18 (28%)
LRR <80..313 CDD:443914 75/361 (21%)
PPP1R42 82..>176 CDD:455733 37/137 (27%)
leucine-rich repeat 83..104 CDD:275378 8/20 (40%)
leucine-rich repeat 105..126 CDD:275378 10/20 (50%)
leucine-rich repeat 127..148 CDD:275378 10/20 (50%)
leucine-rich repeat 149..162 CDD:275378 5/15 (33%)
Lrrc49NP_001423387.1 leucine-rich repeat 160..177 CDD:275380
leucine-rich repeat 180..201 CDD:275380 5/20 (25%)
PPP1R42 183..378 CDD:455733 53/213 (25%)
leucine-rich repeat 202..223 CDD:275380 8/20 (40%)
leucine-rich repeat 224..245 CDD:275380 10/20 (50%)
leucine-rich repeat 246..267 CDD:275380 10/20 (50%)
leucine-rich repeat 268..289 CDD:275380 6/20 (30%)
leucine-rich repeat 290..311 CDD:275380 1/20 (5%)
leucine-rich repeat 312..336 CDD:275380 0/23 (0%)
Blue background indicates that the domain is not in the aligned region.

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