Protein Alignment Ppr-Y and Lrrc43

DIOPT Version :10

• Sequence 1: NP_001015502.3
• Gene: Ppr-Y / 3355180
• FlyBaseID: FBgn0046697
• Length: 569
• Species: Drosophila melanogaster
• Sequence 2: NP_001163867.1
• Gene: Lrrc43 / 288751
• RGDID: 1561461
• Length: 681
• Species: Rattus norvegicus
• Alignment Length: 446
• Identity: 102/446 - (22%)
• Similarity: 171/446 - (38%)
• Gaps: 105/446 - (23%)

  Fly    14 PLVDEVIYPDIEP-----GIINRSLIESSYLKHVHRGEGRRLHQL---EPVVLEQILTMRLEFNN 70
            |..:|.:.|:.|.     |::..|....:.||. ...|.|.|.:|   .|:.::.  |....:..
  Rat    64 PKEEETVGPEEETVEALLGLVRSSHSPWAMLKD-SSAEDRFLRELAIQNPLTIKD--TFFYSYFR 125

  Fly    71 ILRI----------DHLWILPNLTKLCLNCNKIETIENIEMLTNLKDLNLSFNFIEKIENL--DT 123
            .||:          :.|..| .|.:|.|:.|||:.|:...:...||.|.|..|.|..:|.|  ..
  Rat   126 CLRVVDKGVSLVDKEILKFL-KLEELVLSANKIKDIDANNLPPTLKVLELYGNLIASMECLCSPP 189

  Fly   124 LVNLEVLSLFSNK-IEAIENIDMLT----MLVIISLG-NNLIDTVEGIERFRFMNNLKIINLEGN 182
            ..||:.|.|..|| :..:|::.:.:    :||.:.|| |:|.|....|.....:..|:::.|:||
  Rat   190 PPNLQHLGLGHNKLLGPLESLYVTSNNWPLLVSLDLGFNDLTDLQSMILGLSTLKCLRLLVLQGN 254

  Fly   183 PIAKRTNFCLLKYISAILPKLNYYEYTFIKSELRAEACNL-----------YYREIREIEDKQEK 236
            |:             |::|   ||....:.|  .|..|.|           .:|.:....|...:
  Rat   255 PL-------------ALVP---YYRGFTVDS--LARLCVLDDITVSPSEKHQFRGLNSHGDLLAR 301

  Fly   237 EIQARKFLEREQSEAKRLASSFVEHLDG----------HQLFDSLWRGDEDGRVLMLVGTQAQEL 291
            |.|   |:....:....|.||.::...|          :..:|.:...:::|....:.......:
  Rat   302 EAQ---FVVTIGNVRGVLDSSILDPEPGPDGPFISYSYYVTYDFVEDEEKEGITSGMEELHPDSV 363

  Fly   292 ADEYDKDIFELTQEIYKLGLERFTERDEEIRDFFNNLFDGQEELQILGQNEIEWFLQFR----EI 352
            .||.||....:.:|      |...|.:||.|....::|..|...:.:.|....   :||    |:
  Rat   364 LDEIDKPSSGMDEE------EEEEEEEEEDRQEVLSVFQSQAHHRPVRQGGRH---RFRPESPEV 419

  Fly   353 IFEEARIRLLKLEQNSM---HGE------DED----------TPENLKLSDALDKL 389
            :..|....::| |.|.|   .||      ||.          .|:::..|:.|.||
  Rat   420 MSRELSEYIVK-EMNQMAEDSGESGITEVDESETSISIHSAPLPQSIDSSEELAKL 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ppr-Y	NP_001015502.3	leucine-rich repeat	63..82	CDD:275378	5/28 (18%)
		LRR	<80..313	CDD:443914	60/261 (23%)
		PPP1R42	82..>176	CDD:455733	31/101 (31%)
		leucine-rich repeat	83..104	CDD:275378	7/20 (35%)
		leucine-rich repeat	105..126	CDD:275378	8/22 (36%)
		leucine-rich repeat	127..148	CDD:275378	6/25 (24%)
		leucine-rich repeat	149..162	CDD:275378	7/13 (54%)
Lrrc43	NP_001163867.1	leucine-rich repeat	147..168	CDD:275378	7/20 (35%)
		PPP1R42	150..289	CDD:455733	42/156 (27%)
		leucine-rich repeat	169..192	CDD:275378	8/22 (36%)
		leucine-rich repeat	193..219	CDD:275378	6/25 (24%)
		leucine-rich repeat	220..245	CDD:275378	8/24 (33%)