Protein Alignment Ppr-Y and Lrrcc1

DIOPT Version :10

• Sequence 1: NP_001015502.3
• Gene: Ppr-Y / 3355180
• FlyBaseID: FBgn0046697
• Length: 569
• Species: Drosophila melanogaster
• Sequence 2: NP_001094115.3
• Gene: Lrrcc1 / 266808
• RGDID: 628722
• Length: 1025
• Species: Rattus norvegicus
• Alignment Length: 676
• Identity: 141/676 - (20%)
• Similarity: 230/676 - (34%)
• Gaps: 219/676 - (32%)

  Fly    50 LHQLEPVVLEQIL-TMRLEFNNILR---IDHLWILPNLTKLCLNCNKIETIENIEMLTNLKDLNL 110
            ||.:..:.|:..| .:.|..|||.:   |||:|   ||..|.|:.|:|..||.:..||.|..|||
  Rat    28 LHSISELSLDSSLHAINLHCNNISKITSIDHIW---NLRHLDLSSNQISQIEGLNTLTKLCTLNL 89

  Fly   111 SFNFIEKIENLDTLVNLEVLSLFSNKIEAIENI----DMLTMLVIISLGNNLIDTVEGIER---- 167
            |.|.|.::|.|:.||||..|:|..|.|..:..:    .:...|..|.|.:|.||::..:.:
  Rat    90 SCNLITRVEGLEALVNLTRLNLSYNHISDLSGLIPLHGLKYKLRYIDLHSNYIDSIHHLLQCTVG 154

  Fly   168 FRFMNNLKIINL--EGNPIAKRTNFCLLK-YISAILPKLNYYEYTFIKSELRAEACNLYYREIRE 229
            ..|:.|| |:..  |||||      ||:. |.:.||..|         .:||...|...:.|...
  Rat   155 LHFLTNL-ILEKDGEGNPI------CLVPGYRAIILQTL---------PQLRILDCKNIFGEPVS 203

  Fly   230 IEDKQEKEIQARKFL-----------------------------------------EREQSEAKR 253
            :|:.....:|..:.|                                         |...:....
  Rat   204 LEEMNSSHLQCFEGLLDNLVSSDSPLNISEDEVVDNMSAPPIDVLPPLEEFTSTPEENVLTSLLS 268

  Fly   254 LASSFVEHLDGHQLFDSLWRGDE-DGRVLMLVGTQAQELADEY-DKDI-----FELTQE------ 305
            ..||..|.::....|.:..:..: |.::|.|:......|.|.. :||:     .::|.|
  Rat   269 ACSSEPEKINHENNFQNEMKLQKLDDQILQLLNETNNSLIDNVPEKDLRPKRDTDITSESDYGNR 333

  Fly   306 --------------IYKLGLERFTE---------------RDEEIRDFF--------NNLFDGQE 333
                          .|...::....               |...:||.:        |||.:..|
  Rat   334 KECSRKVSRRTKIPYYTRTIQSIKHHNKNNGAFVSCNRKMRQPYLRDLYVRSSLVNCNNLREVDE 398

  Fly   334 EL---------------------QILGQNEIEW--------FLQFREIIFEEARIRLLKLEQNSM 369
            :.                     |:..:.|:.|        .:.:.:.:.::|.      |:..:
  Rat   399 QKNGMIKVDKSASNDNTYRSLVEQLDQEREMRWKAEQTEKKLMDYIDELHKQAN------EKKDV 457

  Fly   370 HGEDEDTPENLKLSDALDK---LNIQFEDAINDLWQAL--MAQELYLHESIQESTINFHRKIAEL 429
            |.:...|.:.||  ||:.|   ...|.|..::.|...:  :..||......||..|...|.:...
  Rat   458 HSQAIITTDRLK--DAIFKERHCKAQLEVIVHRLQNEIKKLTIELMKARDQQEDHIRHLRTLERA 520

  Fly   430 MSKF----VEQSQAFFVQLREITLHFSENMTEILTRFISTKFALQDFDDVPIELRVCVDDRDAIL 490
            :.|.    .:|.||   |:|.|.                           .:||:....||:  :
  Rat   521 LEKMEKQKAQQQQA---QMRLIQ---------------------------EVELKASAADRE--I 553

  Fly   491 NL-----------IAGMKDYHTLRLDEREDTIATR----TKEFVDNMIDQLNSNEVERHRSKILE 540
            ||           :..:.|...|:..|....|.||    ..||.|.:..:| |.|..:|..::.|
  Rat   554 NLLRTSLRQEKEQVQQLHDLLALKEQEHRQEIETREFFNDAEFQDALTKRL-SKEERKHEQEVKE 617

  Fly   541 INFFVEMMTDAMTSLPHDVRDELIAE 566
            ....:.::......|.::.|..|..|
  Rat   618 YQEKINILNQQYLDLENEFRIALTVE 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ppr-Y	NP_001015502.3	leucine-rich repeat	63..82	CDD:275378	8/21 (38%)
		LRR	<80..313	CDD:443914	70/311 (23%)
		PPP1R42	82..>176	CDD:455733	36/101 (36%)
		leucine-rich repeat	83..104	CDD:275378	8/20 (40%)
		leucine-rich repeat	105..126	CDD:275378	10/20 (50%)
		leucine-rich repeat	127..148	CDD:275378	5/24 (21%)
		leucine-rich repeat	149..162	CDD:275378	6/12 (50%)
Lrrcc1	NP_001094115.3	PPP1R42	25..197	CDD:455733	63/187 (34%)
		leucine-rich repeat	40..61	CDD:275378	9/23 (39%)
		leucine-rich repeat	62..83	CDD:275378	8/20 (40%)
		leucine-rich repeat	84..105	CDD:275378	10/20 (50%)
		leucine-rich repeat	106..131	CDD:275378	5/24 (21%)
		leucine-rich repeat	132..145	CDD:275378	6/12 (50%)
		leucine-rich repeat	158..188	CDD:275380	14/45 (31%)
		GumC	<407..>639	CDD:442439	50/272 (18%)
		SMC_prok_B	543..>912	CDD:274008	24/104 (23%)
		CwlO1	830..>1024	CDD:443091