DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ppr-Y and Lrrc23

DIOPT Version :9

Sequence 1:	NP_001015502.3	Gene:	Ppr-Y / 3355180	FlyBaseID:	FBgn0046697	Length:	569	Species:	Drosophila melanogaster
Sequence 2:	XP_006505721.1	Gene:	Lrrc23 / 16977	MGIID:	1315192	Length:	370	Species:	Mus musculus

Alignment Length:	251	Identity:	59/251 - (23%)
Similarity:	119/251 - (47%)	Gaps:	46/251 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 NNSEVQKPLVDEVIYPDIEPGIINRSLIESSYLKHVHRG----EGRRLHQ---LEPVVLEQILTM 64
            :.::::...::|:.|..|.....|: :|::..:.|...|    :|.|:||   |:|..|..:.|:
Mouse   148 DGNQLRSARMNELPYLQIASFSYNQ-IIDTEGIFHPRLGSLDLKGNRIHQVTGLDPERLSSLHTL 211

  Fly    65 RLEFNNILRIDHLWILPNLTKLCLNCNKIETIENIEMLTNLKDLNLSFNFIEKIENLDTLVNLEV 129
            .                      |..|::|:.:.| .|..||:|.|:.|.::|:|.|:.|.||..
Mouse   212 E----------------------LRGNQLESTKGI-YLPKLKNLYLAQNLLKKVEGLENLSNLTT 253

  Fly   130 LSLFSNKIEAIENIDM-LTMLVIISLGNNLIDTVEGIERFRFMNNLKIINLEGNPIAKRTNF--- 190
            |.|..|:||.:..... :..|..::|.:|:|..:..:.:.|.:..|:.:.|..||.|..|::
Mouse   254 LHLRDNQIETLNGFSQEMKSLQYLNLRSNMISDLAELAKLRDLPKLRALVLLDNPCADETDYRQE 318

  Fly   191 CLLKYISAILPKLNYYEYTFIKSELRAEACNLYYREIRE-IEDKQEKEIQARKFLE 245
            .|::     :..|...:..|.:.:.||||     .|||: ::::|::::...:.:|
Mouse   319 ALVQ-----MAHLERLDKEFYEDDDRAEA-----EEIRQRLKEEQDQDLDPDQDME 364

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ppr-Y	NP_001015502.3	leucine-rich repeat	63..82	CDD:275378	1/18 (6%)
		LRR_8	81..137	CDD:290566	19/55 (35%)
		LRR_4	81..121	CDD:289563	12/39 (31%)
		leucine-rich repeat	83..104	CDD:275378	5/20 (25%)
		LRR_4	103..143	CDD:289563	16/39 (41%)
		leucine-rich repeat	105..126	CDD:275378	9/20 (45%)
		LRR_8	126..184	CDD:290566	15/58 (26%)
		LRR_4	126..166	CDD:289563	11/40 (28%)
		leucine-rich repeat	127..148	CDD:275378	6/21 (29%)
		leucine-rich repeat	149..162	CDD:275378	4/12 (33%)
Lrrc23	XP_006505721.1	leucine-rich repeat	100..119	CDD:275380
		internalin_A	105..>311	CDD:380193	45/186 (24%)
		leucine-rich repeat	120..141	CDD:275380
		leucine-rich repeat	142..162	CDD:275380	1/13 (8%)
		leucine-rich repeat	163..183	CDD:275380	4/20 (20%)
		leucine-rich repeat	184..207	CDD:275380	8/22 (36%)
		leucine-rich repeat	208..228	CDD:275380	6/42 (14%)
		leucine-rich repeat	229..250	CDD:275380	9/20 (45%)
		leucine-rich repeat	251..273	CDD:275380	6/21 (29%)
		leucine-rich repeat	274..298	CDD:275380	5/23 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836018
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930