DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ppr-Y and LRRC23

DIOPT Version :9

Sequence 1:NP_001015502.3 Gene:Ppr-Y / 3355180 FlyBaseID:FBgn0046697 Length:569 Species:Drosophila melanogaster
Sequence 2:NP_001128689.1 Gene:LRRC23 / 10233 HGNCID:19138 Length:343 Species:Homo sapiens


Alignment Length:259 Identity:66/259 - (25%)
Similarity:111/259 - (42%) Gaps:42/259 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    21 YPDIEPGIINRSLIESSYLKHV--HRGEGRRLHQLEPVVLEQILTMRLEFNNIL---RIDHLWIL 80
            |.||....:. .|...:||.|:  .:.:|.||...:...|..:......:|.|.   .|.|    
Human    95 YVDISENHLT-DLSPLNYLTHLLWLKADGNRLRSAQMNELPYLQIASFAYNQITDTEGISH---- 154

  Fly    81 PNLTKLCLNCNKIETIENI--EMLTNLKDLNLSFNFIEKIENLDTLVNLEVLSLFSNKIEAIENI 143
            |.|..|.|..|.|..:..:  |.|.:|..:.|..|.:|....:: |..|:.|.|..|.::.:|.:
Human   155 PRLETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLESTLGIN-LPKLKNLYLAQNMLKKVEGL 218

  Fly   144 DMLTMLVIISLGNNLIDTVEGIERFRFMNNLKIINLEGNPIAKRTNFCLLKYISAI--------- 199
            :.|:.|..:.|.:|.|||:.|..  |.|.:|:.:||.||.:|.......|:.:..:         
Human   219 EDLSNLTTLHLRDNQIDTLSGFS--REMKSLQYLNLRGNMVANLGELAKLRDLPKLRALVLLDNP 281

  Fly   200 --------------LPKLNYYEYTFIKSELRAEACNLYYREIREIEDKQEKEIQARKFLEREQS 249
                          :|.|...:..|.:.|.||||..:..|    :::::|:|.:.::.||.|||
Human   282 CTDETSYRQEALVQMPYLERLDKEFYEEEERAEADVIRQR----LKEEKEQEPEPQRDLEPEQS 341

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ppr-YNP_001015502.3 leucine-rich repeat 63..82 CDD:275378 4/21 (19%)
LRR_8 81..137 CDD:290566 17/57 (30%)
LRR_4 81..121 CDD:289563 12/41 (29%)
leucine-rich repeat 83..104 CDD:275378 7/22 (32%)
LRR_4 103..143 CDD:289563 10/39 (26%)
leucine-rich repeat 105..126 CDD:275378 5/20 (25%)
LRR_8 126..184 CDD:290566 20/57 (35%)
LRR_4 126..166 CDD:289563 13/39 (33%)
leucine-rich repeat 127..148 CDD:275378 6/20 (30%)
leucine-rich repeat 149..162 CDD:275378 5/12 (42%)
LRRC23NP_001128689.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..47
LRR 1 92..113 5/18 (28%)
leucine-rich repeat 93..114 CDD:275380 6/19 (32%)
LRR 2 114..134 4/19 (21%)
leucine-rich repeat 115..135 CDD:275380 4/19 (21%)
LRR 3 135..155 4/23 (17%)
leucine-rich repeat 136..156 CDD:275380 4/23 (17%)
LRR 4 156..177 5/20 (25%)
leucine-rich repeat 157..180 CDD:275380 7/22 (32%)
LRR 5 180..200 4/20 (20%)
leucine-rich repeat 181..201 CDD:275380 5/20 (25%)
LRR_8 200..255 CDD:290566 18/56 (32%)
LRR_4 200..241 CDD:289563 13/40 (33%)
LRR 6 201..222 5/20 (25%)
leucine-rich repeat 202..223 CDD:275380 6/20 (30%)
LRR_4 223..265 CDD:289563 15/43 (35%)
LRR 7 223..244 8/22 (36%)
leucine-rich repeat 224..246 CDD:275380 9/23 (39%)
LRR 8 246..267 6/20 (30%)
leucine-rich repeat 247..271 CDD:275380 7/23 (30%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 318..343 8/28 (29%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165145940
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.930

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