Protein Alignment ORY and Ccdc110

DIOPT Version :10

• Sequence 1: NP_001015498.5
• Gene: ORY / 3355174
• FlyBaseID: FBgn0046323
• Length: 914
• Species: Drosophila melanogaster
• Sequence 2: XP_038950822.1
• Gene: Ccdc110 / 290755
• RGDID: 1564538
• Length: 878
• Species: Rattus norvegicus
• Alignment Length: 963
• Identity: 189/963 - (19%)
• Similarity: 345/963 - (35%)
• Gaps: 280/963 - (29%)

  Fly    92 NEVLRPQILSSEKKLRLALELTSTSEEAMQKLKDLLGDAWKESDASALREQLVQE-KLQEVLIKC 155
            ::.:..:|||...:..|.   :|:|.:|      :||        |...:.||:| .:..:|:..
  Rat    13 DQTVGKEILSDRNEPGLP---SSSSPKA------VLG--------SVPEKHLVEEDDVDSILLSA 60

  Fly   156 EGLADRNSGTTD---DTAEFGHLAKYKNIILRERDRLAGEVV--DLEKRLATNRYYSENLEYIIR 215
            ..:.:.:.|..:   ...|:|..::.:|.|   :.:.|.:|:  .||...|......:|:..:..
  Rat    61 SKILNASEGVKESGGSEPEYGCASEPENQI---QPQSALKVLQHQLESFQALRMQTLQNVSMVQS 122

  Fly   216 NNEDAMSKMASRAKFAEGERLNVESKLRALM--------KTMEE----QKEAHGKTMMKLDIANR 268
            ...:.::|....   .|..:||.|..|...|        ||.||    :|..|.:....|.....
  Rat   123 EISEILNKSIVE---VENPQLNSEKNLIFSMHPEKDLPNKTQEEILCTKKSNHFENPKTLHSMEE 184

  Fly   269 ELSETT-RKLSQKIS----------------------------------DYDRQRVH-------- 290
            ..|..: ..|||.|:                                  .:.|:..|
  Rat   185 NFSSNSGTDLSQSINIPPQTQVKDVVAVESLRTTAGNSPPSKAVNTSEQPHTRKGFHFYQFLPLP 249

  Fly   291 ------------LDKYRSEVNALNKAMHKNEDDISDLTKN-----QKNNEE---MIKQLRLIEKE 335
                        |||..:.|..|.....:|.|||....|:     ||:|::   :..:|...:.:
  Rat   250 PQTAVPQAAPMILDKSTTTVPFLKHEFCENLDDICHSIKHMKEELQKSNDQELALTNELHNFQMD 314

  Fly   336 K--------------SNAVSQLTSRLKKSIEDQNNATTRMYKLNRKVMMLNSEILRLKNNINSLE 386
            .              |..:|.:.....|....:::.:.|:.:|...|    |::|.|::.::.|.
  Rat   315 GRTHSHHKHELFPICSAKLSFIPEENTKGNLSEDSKSKRISELEALV----SKLLPLRDTVSKLH 375

  Fly   387 KDVLNANGRTDDIRRIKETLQRERDSLRSDIIKLNNTMADLKHDMMLKANMISSLNLDMNKLNVK 451
               :|...:...:.| .|..:.::.....||...:..:.|||.......:.:|.|:...:|:..|
  Rat   376 ---VNFCRKCKKLSR-SEICRGKKSEKNKDIPITSKNIIDLKFHSRAPRHTLSVLDPGKHKIKDK 436

  Fly   452 LDEAYILKSKAEKERDEMAQEMETLHER-------IENY---------------QDQISLKTSQV 494
            ..:|:|:..:.....:|...:.:.:.|:       ::||               .:.::|:| ::
  Rat   437 EGQAFIISQEPVTFENEKTPKDKCVPEQCVAKIQYLQNYLKESLQYQKKMTELENENLALRT-KM 500

  Fly   495 NDLTEKLHEKQREVHSYKKQLESVHSEKMMLQRNLENTTQERDNFRILQAKSGHQIQQLTTEISA 559
            ..|........::..:::|||:|:..||..||..|....:|..:.          :::|.|.||.
  Rat   501 KPLVFTAQSLIQKAETHEKQLKSLTEEKSSLQSQLTKAEEENKDC----------LRELKTLIST 555

  Fly   560 NEV----------KINSLNLK-------IEHLNNYIKELQSDLKNKEN-------LVAALRKDMR 600
            ..|          |.:.|:|:       |:||.......|||:...:|       .:.|::..|.
  Rat   556 YNVLQGQHKMLEEKNSQLSLEKQQMLETIDHLKGKEHRTQSDMAALQNENGRMTIEIEAMKTSML 620

  Fly   601 EMKAKNEMLAKTISNDELKFMKMGHELEEMRKERNLVGLQMVRRNDEIVVIKEKLQIAQNALDNG 665
            ..:.:.|||.|    |..:.:|....||...||..|          ||:.:|||.::|
  Rat   621 LTRDEREMLEK----DMYQLLKDKGTLEGDLKESKL----------EILQLKEKEELA------- 664

  Fly   666 TTQYNQRVEDIRLLKKEISNLHTESECLKHAIKSTADMRKEIVRLQRALNQEHIRIRALTEDART 730
                                 |.|.|.|.|.:.:.   :.|.:||:..| ||....|.:.|  |.
  Rat   665 ---------------------HAEQESLLHILDAA---KAEKLRLEATL-QESASARQMLE--RE 702

  Fly   731 PTGVHRWRILKGEDPKKFELLEKLQLLQKRSLKQSIENSNLKNKLCEAQKTNETLKRMLSHMPTV 795
            ...:..:|          ..:|:..|...:|.|.  |.|..||.|.|..|..|.|.:|:     :
  Rat   703 LVEIQTYR----------SAVEEKFLKDIKSAKS--ETSIYKNNLAEISKECEVLSKMV-----M 750

  Fly   796 EIKHKLVVQQRINRQMAKKLKTLAAERSLDMVELKSRQCIINSFAGKISEIGELSILSDGKNEIK 860
            |||        .:.|:.|:             |||........|...||.:.|..:|.:  |.::
  Rat   751 EIK--------ADNQILKE-------------ELKKHSQENTKFENSISRLTEDKVLLE--NYVR 792

  Fly   861 SAILDVKNEIS--KSNMSLVPQEYMECGLFSDADTKTSTMCAKLTDILNSEVF 911
            |    ::||.:  :..|..:.::|:.   .|:..:..:...:|.|.|...|.|
  Rat   793 S----IENERNTLEFEMRTLQRDYIN---LSEKVSGQNNSASKSTYISRREKF 838

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ORY	NP_001015498.5	SMC_N	<111..435	CDD:481474	74/418 (18%)
		DR0291	290..>417	CDD:441187	28/168 (17%)
		SMC_prok_B	<363..686	CDD:274008	71/368 (19%)
Ccdc110	XP_038950822.1	Smc	<518..>811	CDD:440809	91/394 (23%)