DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pp1-Y2 and PPZ2

DIOPT Version :9

Sequence 1:	NP_001015497.4	Gene:	Pp1-Y2 / 3355173	FlyBaseID:	FBgn0046698	Length:	313	Species:	Drosophila melanogaster
Sequence 2:	NP_010724.1	Gene:	PPZ2 / 852046	SGDID:	S000002844	Length:	710	Species:	Saccharomyces cerevisiae

Alignment Length:	318	Identity:	180/318 - (56%)
Similarity:	235/318 - (73%)	Gaps:	12/318 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 TLTELN--------NIDQLILRIID----TRRLKQLNLTETDIRLLCNRSREVFMSQPMLLELSA 59
            |:.|:.        :||::|.|::|    .:|.|.:.|..::|..:|:::||:|::||.|||||.
Yeast   383 TMVEMKRKKPVRPVDIDEIIQRLLDAGYAAKRTKNVCLKNSEIIQICHKARELFLAQPALLELSP 447

  Fly    60 PVKICGDIHGQFTDLLRLFDYGGYPPASNYLFLGDYVDRGKQSIETMCLLLAYKIKYPENFFLLR 124
            .|||.||:|||:.||||||...|:||.:|||||||||||||||:||:.|||.|||||||||||||
Yeast   448 SVKIVGDVHGQYADLLRLFTKCGFPPMANYLFLGDYVDRGKQSLETILLLLCYKIKYPENFFLLR 512

  Fly   125 GNHESAGINRIYGFYDECKRRYTIKLWRTFVDCYSCMPVSAIVDEKIFCCHGGLSPDLLNMNQIG 189
            ||||.|.:.|:||||||||||..||:|:||||.::.:|::|||..||||.||||||.|.:|::|.
Yeast   513 GNHECANVTRVYGFYDECKRRCNIKIWKTFVDTFNTLPLAAIVTGKIFCVHGGLSPVLNSMDEIR 577

  Fly   190 QLARPCDVPDKGLLCDLLWSDPDPKIMGWSDNDRGVSVTFGADIVGKFVHRHKFDLICRAHQVVE 254
            .::||.||||.||:.|||||||......|.||:||||..:....:.||:::..|||:||||.|||
Yeast   578 HVSRPTDVPDFGLINDLLWSDPTDSSNEWEDNERGVSFCYNKVAINKFLNKFGFDLVCRAHMVVE 642

  Fly   255 DGYEFFAKRQLITIFSAPNYCGEFDNAGAMMSVDETLMCSFYVLKPSKKPGLRKIHSK 312
            ||||||..|.|:|:||||||||||||.||:|:|.|.|:|||.:|.|.....|:::..|
Yeast   643 DGYEFFNDRSLVTVFSAPNYCGEFDNWGAVMTVSEGLLCSFELLDPLDSTALKQVMKK 700

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pp1-Y2	NP_001015497.4	PTZ00480	10..303	CDD:185658	177/304 (58%)
Pp1-Y2	NP_001015497.4	MPP_PP1_PPKL	13..300	CDD:277359	175/290 (60%)
PPZ2	NP_010724.1	MPP_PP1_PPKL	397..688	CDD:277359	175/290 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S19
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100222
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.760