Protein Alignment Pp1-Y2 and PPP3CB

DIOPT Version :10

• Sequence 1: NP_001015497.4
• Gene: Pp1-Y2 / 3355173
• FlyBaseID: FBgn0046698
• Length: 313
• Species: Drosophila melanogaster
• Sequence 2: XP_047281382.1
• Gene: PPP3CB / 5532
• HGNCID: 9315
• Length: 534
• Species: Homo sapiens
• Alignment Length: 312
• Identity: 110/312 - (35%)
• Similarity: 172/312 - (55%)
• Gaps: 24/312 - (7%)

  Fly     2 SLQMTTLTELNNIDQLILRIIDTRRLKQLNLTETDIRLLCNRSREVFMSQPMLLELSAPVKICGD 66
            |.::..|..:..:|.|...::...|:.:    |..:|:: |....:...:..::|:.||:.:|||
Human    40 SEEVFDLDGIPRVDVLKNHLVKEGRVDE----EIALRII-NEGAAILRREKTMIEVEAPITVCGD 99

  Fly    67 IHGQFTDLLRLFDYGGYPPASNYLFLGDYVDRGKQSIETMCLLLAYKIKYPENFFLLRGNHESAG 131
            |||||.||::||:.||.|..:.|||||||||||..|||.:..|...||.||...||||||||...
Human   100 IHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRH 164

  Fly   132 INRIYGFYDECKRRYTIKLWRTFVDCYSCMPVSAIVDEKIFCCHGGLSPDLLNMNQIGQLARPCD 196
            :...:.|..|||.:|:.:::...::.:..:|::|:::::..|.||||||::..::.|.:|.|..:
Human   165 LTEYFTFKQECKIKYSERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKE 229

  Fly   197 VPDKGLLCDLLWSDPDPKIMG------WSDND-RGVSVTFGADIVGKFVHRHKFDLICRAHQVVE 254
            .|..|.:||||||||......      :|.|. ||.|..:....|.:|:..:....|.|||:..:
Human   230 PPAFGPMCDLLWSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQD 294

  Fly   255 DGYEFFAKRQ------LITIFSAPNYCGEFDNAGAMMSVDETLM------CS 294
            .||..:.|.|      ||||||||||...::|..|::..:..:|      ||
Human   295 AGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCS 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pp1-Y2	NP_001015497.4	MPP_PP1_PPKL	13..300	CDD:277359	108/301 (36%)
PPP3CB	XP_047281382.1	MPP_PP2B	50..354	CDD:277361	108/302 (36%)