Protein Alignment Pp1-Y2 and PPP4C

DIOPT Version :10

• Sequence 1: NP_001015497.4
• Gene: Pp1-Y2 / 3355173
• FlyBaseID: FBgn0046698
• Length: 313
• Species: Drosophila melanogaster
• Sequence 2: NP_002711.1
• Gene: PPP4C / 5531
• HGNCID: 9319
• Length: 307
• Species: Homo sapiens
• Alignment Length: 311
• Identity: 131/311 - (42%)
• Similarity: 198/311 - (63%)
• Gaps: 24/311 - (7%)

  Fly     8 LTELNNIDQLILRIIDTRRLKQLN----LTETDIRLLCNRSREVFMSQPMLLELSAPVKICGDIH 68
            :.|::::|         |:::||.    :.|::::.||.::||:.:.:..:..:.:||.:|||||
Human     1 MAEISDLD---------RQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIH 56

  Fly    69 GQFTDLLRLFDYGGYPPASNYLFLGDYVDRGKQSIETMCLLLAYKIKYPENFFLLRGNHESAGIN 133
            |||.||..||..||..|.:||||:||:||||..|:||..||||.|::||:...|:||||||..|.
Human    57 GQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQIT 121

  Fly   134 RIYGFYDECKRRY-TIKLWRTFVDCYSCMPVSAIVDEKIFCCHGGLSPDLLNMNQIGQLARPCDV 197
            ::|||||||.|:| ::.:||...:.:..:.:|||:|.||||.||||||.:..::||..:.|..:|
Human   122 QVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEV 186

  Fly   198 PDKGLLCDLLWSDPDPKIMGWSDNDRGVSVTFGADIVGKFVHRHKFDLICRAHQVVEDGYEFFAK 262
            |..|.:||||||||: ...||..:.||....||:|:|.:|...:..|:||||||:|.:||::...
Human   187 PHDGPMCDLLWSDPE-DTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFN 250

  Fly   263 RQLITIFSAPNYCGEFDNAGAMMSVDETLMCSFYVLK---------PSKKP 304
            ..::|::||||||....|..|::.:||.|...|.:.:         |||||
Human   251 ETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQETRGIPSKKP 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pp1-Y2	NP_001015497.4	MPP_PP1_PPKL	13..300	CDD:277359	125/300 (42%)
PPP4C	NP_002711.1	MPP_PP2A_PP4_PP6	6..290	CDD:277360	125/293 (43%)