DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pp1-Y2 and rdgC

DIOPT Version :9

Sequence 1:	NP_001015497.4	Gene:	Pp1-Y2 / 3355173	FlyBaseID:	FBgn0046698	Length:	313	Species:	Drosophila melanogaster
Sequence 2:	NP_536738.3	Gene:	rdgC / 40224	FlyBaseID:	FBgn0265959	Length:	746	Species:	Drosophila melanogaster

Alignment Length:	318	Identity:	106/318 - (33%)
Similarity:	160/318 - (50%)	Gaps:	33/318 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 NNIDQLILRIIDTRRLKQLNLTETDIRLLCNRSREVFMSQ-----PMLLELSAPVKICGDIHGQF 71
            |:||.|    ||..|.|:.|........|..|.....:.|     |:...:|..|.:|||:||:.
  Fly   188 NHIDLL----IDVFRKKRGNRLHPKYVALILREAAKSLKQLPNISPVSTAVSQQVTVCGDLHGKL 248

  Fly    72 TDLLRLFDYGGYPPASN-YLFLGDYVDRGKQSIETMCLLLAYKIKYPENFFLLRGNHESAGINRI 135
            .|||.:....|.|.:|| |:|.||:|||||:.:|.:.|||:..:.:|...||.|||||.:.:|..
  Fly   249 DDLLVVLHKNGLPSSSNPYVFNGDFVDRGKRGLEVLLLLLSLYLAFPNAVFLNRGNHEDSVMNAR 313

  Fly   136 YGFYDECKRRY--TIKLWRTFVD-CYSCMPVSAIVDEKIFCCHGGLSPDLLNMNQIGQLAR---- 193
            |||..|.:.:|  ..|....|:| .|..:|:.::::.::...|||.| |..:::.|..:.|
  Fly   314 YGFIREVESKYPRNHKRILAFIDEVYRWLPLGSVLNSRVLIVHGGFS-DSTSLDLIKSIDRGKYV 377

  Fly   194 -----------PCDVPDKGLLCDLLWSDPDPKIMGWSDND-RGVSVTFGADIVGKFVHRHKFDLI 246
                       |.|..:...:.|::||||. ..||...|. ||..|.||.|:...|:.||:...:
  Fly   378 SILRPPLTDGEPLDKTEWQQIFDIMWSDPQ-ATMGCVPNTLRGAGVWFGPDVTDNFLQRHRLSYV 441

  Fly   247 CRAHQVVEDGYEFFAKRQLITIFSAPNYCGEFDNAGAMMSVDETLMCSF--YVLKPSK 302
            .|:|:...:|:||....::||||||.||.....|.||.:.::..||..|  |:...|:
  Fly   442 IRSHECKPNGHEFMHDNKIITIFSASNYYAIGSNKGAYIRLNNQLMPHFVQYISAASQ 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pp1-Y2	NP_001015497.4	PTZ00480	10..303	CDD:185658	106/318 (33%)
Pp1-Y2	NP_001015497.4	MPP_PP1_PPKL	13..300	CDD:277359	104/313 (33%)
rdgC	NP_536738.3	IQ	89..111	CDD:197470
		MPP_RdgC	184..494	CDD:277364	104/311 (33%)
		EFh	616..681	CDD:238008
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438731
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.840