DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pp1-Y2 and Ppef1

DIOPT Version :9

Sequence 1:	NP_001015497.4	Gene:	Pp1-Y2 / 3355173	FlyBaseID:	FBgn0046698	Length:	313	Species:	Drosophila melanogaster
Sequence 2:	XP_038955765.1	Gene:	Ppef1 / 317498	RGDID:	1562772	Length:	664	Species:	Rattus norvegicus

Alignment Length:	393	Identity:	105/393 - (26%)
Similarity:	169/393 - (43%)	Gaps:	83/393 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SLQMTTLTELNNIDQ-LILRIIDTRRLK----------------------QLNLTETDIRLLCN- 42
            |..:...|..:..|. |:.|:.:..||:                      |..||.|||.||..
  Rat    88 SFMLENYTNTHKEDSALVSRLFENTRLESKDREEYVGLIDVPDSYDGPRLQFPLTFTDINLLLQA 152

  Fly    43 -----------------RSREVFMSQPMLLELSA-PVK---ICGDIHGQFTDLLRLFDYGGYPPA 86
                             .:|::....|....:.. |.|   ||||:||:..||:.:|...|.|..
  Rat   153 FKQQQTLHAHYVLEVLFEARKILKQMPNFTRIQTFPAKEITICGDLHGKLDDLMLIFYKNGLPSE 217

  Fly    87 SN-YLFLGDYVDRGKQSIETMCLLLAYKIKYPENFFLLRGNHESAGINRIYGFYDECKRRYTI-- 148
            .| |:|.||:||||..|:|.:.:||...:.||.:..|.|||||...:|..|||..|..::|.:
  Rat   218 KNPYVFNGDFVDRGNNSMEILMILLVSFLVYPTDLHLNRGNHEDFMMNLRYGFTKEILQKYKLHG 282

  Fly   149 -KLWRTFVDCYSCMPVSAIVDEKIFCCHGGLSPDLLNMNQIGQLAR---------------PCDV 197
             |:.:...:.|:.:|:..|:|.:|...|||:| :..::|.:.||.|               .|::
  Rat   283 KKILQVLEELYTWLPIGTIIDNEILVIHGGIS-ESTDLNILQQLQRNKMKSVLMPPMSTNQECNI 346

  Fly   198 PDKGL------------------LCDLLWSDPDPKIMGWSDNDRGVSVTFGADIVGKFVHRHKFD 244
            .....                  :.|||||||..|...:.:..||....||.|:..|.:::::..
  Rat   347 KKNKAGPSEQSASEQLTKLEWEQIIDLLWSDPRGKKGCYPNTSRGGGCYFGPDVTSKVLNKNQLK 411

  Fly   245 LICRAHQVVEDGYEFFAKRQLITIFSAPNYCGEFDNAGAMMSVDETLMCSFYVLKPSKKPGLRKI 309
            ::.|:|:...||||.....::||:|||.||..|..|.||.:.:.......|:..:.:....|..:
  Rat   412 MVIRSHECKPDGYEICHDGKVITVFSASNYYEEGSNRGAYIRLSYGTSPQFFQYQVTSTSCLNPL 476

  Fly   310 HSK 312
            :.:
  Rat   477 YQR 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pp1-Y2	NP_001015497.4	PTZ00480	10..303	CDD:185658	102/374 (27%)
Pp1-Y2	NP_001015497.4	MPP_PP1_PPKL	13..300	CDD:277359	102/368 (28%)
Ppef1	XP_038955765.1	IQ	40..>57	CDD:197470
		MPP_RdgC	140..466	CDD:277364	96/326 (29%)
		PTZ00183	505..647	CDD:185503
		EF-hand_7	582..650	CDD:404394
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910