DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pp1-Y2 and Ppp1ca

DIOPT Version :9

Sequence 1:	NP_001015497.4	Gene:	Pp1-Y2 / 3355173	FlyBaseID:	FBgn0046698	Length:	313	Species:	Drosophila melanogaster
Sequence 2:	NP_114074.1	Gene:	Ppp1ca / 19045	MGIID:	103016	Length:	330	Species:	Mus musculus

Alignment Length:	316	Identity:	226/316 - (71%)
Similarity:	266/316 - (84%)	Gaps:	15/316 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 TELNNIDQLILRIID---TRRLKQLNLTETDIRLLCNRSREVFMSQPMLLELSAPVKICGDIHGQ 70
            :|..|:|.:|.|:::   :|..|.:.|||.:||.||.:|||:|:|||:||||.||:|||||||||
Mouse     4 SEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQ 68

  Fly    71 FTDLLRLFDYGGYPPASNYLFLGDYVDRGKQSIETMCLLLAYKIKYPENFFLLRGNHESAGINRI 135
            :.||||||:|||:||.||||||||||||||||:||:||||||||:|||||||||||||.|.||||
Mouse    69 YYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIRYPENFFLLRGNHECASINRI 133

  Fly   136 YGFYDECKRRYTIKLWRTFVDCYSCMPVSAIVDEKIFCCHGGLSPDLLNMNQIGQLARPCDVPDK 200
            |||||||||||.||||:||.||::|:|::||||||||||||||||||.:|.||.::.||.||||:
Mouse   134 YGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQ 198

  Fly   201 GLLCDLLWSDPDPKIMGWSDNDRGVSVTFGADIVGKFVHRHKFDLICRAHQVVEDGYEFFAKRQL 265
            ||||||||||||..:.||.:||||||.||||::|.||:|:|..||||||||||||||||||||||
Mouse   199 GLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQL 263

  Fly   266 ITIFSAPNYCGEFDNAGAMMSVDETLMCSFYVLKPSKK------------PGLRKI 309
            :|:|||||||||||||||||||||||||||.:|||:.|            ||.|.|
Mouse   264 VTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPI 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pp1-Y2	NP_001015497.4	PTZ00480	10..303	CDD:185658	221/295 (75%)
Pp1-Y2	NP_001015497.4	MPP_PP1_PPKL	13..300	CDD:277359	218/289 (75%)
Ppp1ca	NP_114074.1	PTZ00480	6..308	CDD:185658	221/301 (73%)
		MPP_PP1_PPKL	8..298	CDD:277359	218/289 (75%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	306..330		4/14 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S19
OMA	1	1.010	-	-		QHG53795
OrthoDB	1	1.010	-	-		D327461at33208
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100222
Panther	1	1.100	-	-	O	PTHR11668
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.880