DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pp1-Y2 and F49E11.7

DIOPT Version :9

Sequence 1:	NP_001015497.4	Gene:	Pp1-Y2 / 3355173	FlyBaseID:	FBgn0046698	Length:	313	Species:	Drosophila melanogaster
Sequence 2:	NP_502500.3	Gene:	F49E11.7 / 186051	WormBaseID:	WBGene00009893	Length:	384	Species:	Caenorhabditis elegans

Alignment Length:	317	Identity:	114/317 - (35%)
Similarity:	169/317 - (53%)	Gaps:	38/317 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 MTTLTELNNIDQLILRIIDTR---RLKQLNLTETDIRLLCNRSREVFMSQPMLLELSAPVKICGD 66
            ||...::.:|::.:.|.:..:   ..:|.:.|:.::..|.............|.::|.||.|.||
Worm     1 MTDDKKMFDINEFLKRHLFVKNWVNYRQQSYTKYELMQLIESVEAALSVDDTLAKISPPVTIVGD 65

  Fly    67 IHGQFTDLLRLF-------------DYGGYPPASNYLFLGDYVDRGKQSIETMCLLLAYKIKYPE 118
            ||||:.||:|:.             .||..  .|.::|||||||||..|||.:.|:.|.|:.||.
Worm    66 IHGQYPDLVRVLCNQNSKEDAKKKAAYGFC--NSRFVFLGDYVDRGHHSIECISLVFALKVVYPT 128

  Fly   119 NFFLLRGNHESAGINRIYGFYDECKRRY----TIKLWRTFVDCYSCMPVSAIVDEKIFCCHGGLS 179
            |:.|||||||:..||..|||.:|...|.    ..::|..|...:|.||::.:|..||.|.|||:|
Worm   129 NYILLRGNHETKSINYTYGFREELVNRLGPIDGFEIWERFNVAFSWMPLACLVGHKILCMHGGIS 193

  Fly   180 PDLLNMNQIGQLARPCD--VPDKGLLCDLLWSDP-----------DPKIMGWSDNDRGVSVTFGA 231
            |.|.::.:|.::.||..  :|| .|..||||:||           .|:.:  .:..||:|..|..
Worm   194 PKLHSLKEINEIDRPVAEILPD-SLAQDLLWADPADGQGAMTVRSTPEYV--PNGVRGLSFIFNE 255

  Fly   232 DIVGKFVHRHKFDLICRAHQVVEDGYEFFAKRQLITIFSAPNYCGEFDNAGAMMSVD 288
            ..|.....|...:||.||||::.:|::|||.::|:||||||.|..|.||.||.:.|:
Worm   256 AAVRDTCKRLNINLIVRAHQMIPEGFKFFADQKLLTIFSAPRYMNETDNHGATLRVE 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pp1-Y2	NP_001015497.4	PTZ00480	10..303	CDD:185658	112/312 (36%)
Pp1-Y2	NP_001015497.4	MPP_PP1_PPKL	13..300	CDD:277359	112/309 (36%)
F49E11.7	NP_502500.3	PP2Ac	31..326	CDD:197547	109/287 (38%)
F49E11.7	NP_502500.3	MPP_PPP_family	61..311	CDD:277316	102/254 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53795
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11668
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.020