DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pp1-Y2 and R13A5.11

DIOPT Version :9

Sequence 1:	NP_001015497.4	Gene:	Pp1-Y2 / 3355173	FlyBaseID:	FBgn0046698	Length:	313	Species:	Drosophila melanogaster
Sequence 2:	NP_001299879.1	Gene:	R13A5.11 / 176075	WormBaseID:	WBGene00020053	Length:	459	Species:	Caenorhabditis elegans

Alignment Length:	314	Identity:	122/314 - (38%)
Similarity:	186/314 - (59%)	Gaps:	7/314 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSLQMTTLTELNNIDQL--ILRIIDTRRLKQLNLTETDIRLLCNRSREVFMSQPMLLELSAPVKI 63
            |:.|..|...::.:|.|  ..::|.. .:.::..|:.:...:...::.:|.|:..|:::..|..:
Worm   132 MTAQNRTQERIDFVDFLDRHYQVIQA-GVHKIQYTKEEFENVIYEAQTIFSSEKALVDIDPPCVV 195

  Fly    64 CGDIHGQFTDLLRLFDYGGYPPASNYLFLGDYVDRGKQSIETMCLLLAYKIKYPENFFLLRGNHE 128
            .||:||||.||:.:|...|.||.:.|:|.|||||||..|:|.:.||..|||.||||..|||||||
Worm   196 VGDLHGQFNDLINMFILLGRPPETVYVFTGDYVDRGMMSLECIMLLFTYKICYPENIVLLRGNHE 260

  Fly   129 SAGINRIYGFYDECKR---RYTIKLWRTFVDCYSCMPVSAIVDEKIFCCHGGLSPDLLNMNQIGQ 190
            .|.:|:.||||:||..   :...::|..|..|::.:|:||::..||.|.||||||.|..::::..
Worm   261 IARVNKKYGFYEECVTSIPKCGEEIWALFQRCFNNLPISALIATKILCMHGGLSPALTCLDELRN 325

  Fly   191 LARPCDVPDKGLLCDLLWSDPDPKIMGWSDNDRGVSVTFGADIVGKFVHRHKFDLICRAHQVVED 255
            ..:|...|.:|::.|:||:||||.:..|..:.||...|||.:::.....|...:||.||||:..|
Worm   326 HPKPIRNPFRGIVNDMLWADPDPSVFEWKASSRGSGFTFGTNVIDDVCKRLGVELIIRAHQMCFD 390

  Fly   256 GYEFFAKRQLITIFSAPNYCGEFDNAGAMMSVDETLMCSFYVLKPSKKPGLRKI 309
            ||...:.|:||||||||.||..:.|||.::.|||||........|:.: .:.||
Worm   391 GYWVLSGRKLITIFSAPMYCNFYKNAGCVLKVDETLGIQMIAFVPASE-NIEKI 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pp1-Y2	NP_001015497.4	PTZ00480	10..303	CDD:185658	117/297 (39%)
Pp1-Y2	NP_001015497.4	MPP_PP1_PPKL	13..300	CDD:277359	116/291 (40%)
R13A5.11	NP_001299879.1	PP2Ac	164..437	CDD:197547	114/272 (42%)
R13A5.11	NP_001299879.1	MPP_PPP_family	194..422	CDD:277316	103/227 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D327461at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11668
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020