Protein Alignment FucTC and Pofut3

DIOPT Version :10

• Sequence 1: NP_001036320.3
• Gene: FucTC / 3355171
• FlyBaseID: FBgn0044872
• Length: 425
• Species: Drosophila melanogaster
• Sequence 2: NP_001012535.1
• Gene: Pofut3 / 171167
• MGIID: 2384748
• Length: 481
• Species: Mus musculus
• Alignment Length: 450
• Identity: 107/450 - (23%)
• Similarity: 159/450 - (35%)
• Gaps: 134/450 - (29%)

  Fly    42 LLLLVLLGVLVVLHKVTQSPLLNQNKILQD----------HLR--GQHERYIQSTRT-------- 86
            :.|:|.|.|:|.|.|..:..|.:.|  :||          ||.  .:.|....:.||
Mouse    20 VFLMVTLQVVVELGKFERKKLKDSN--VQDGHRDVEGEPKHLEPFPEKEALALAGRTKVDAGSYP 82

  Fly    87 ILLW-------TEFFGDSRWKLSWDTLGPQELRDELHCPV------YQCEISNQNAFLPAVELYD 138
            |:||       |...|.......:.|:.    |...|.|:      |..:.:..:..||....:|
Mouse    83 IVLWWSPLTGETGRLGQCGADACFFTIN----RTFQHHPMTRAFLFYGTDFNIDSLPLPREAHHD 143

  Fly   139 AIVFHAAEMFPLLRPVPSQRSPHQVYVFALMEPPGETKHRLDDEQGFYNLTMTYRIDSDVFWPYG 203
            ..:||             :.||...|  .|...|..|         .:|.|.|:...|.
Mouse   144 WALFH-------------EESPKNNY--KLFHKPVIT---------LFNHTATFSRHSH------ 178

  Fly   204 QLLDITADAVVAPSVKPPWR-KPPVAFNDSLVWDLWSGKTKTAAWFVSHCETLSKREVLANRLQE 267
              |.:|...:....|....| ..|:...::|     ..|.....:..|.|:..|.|:.....|..
Mouse   179 --LPLTTQYLEGVDVLKSLRYLVPLQAKNNL-----RQKLAPLVYVQSDCDPPSDRDSYVRELMA 236

  Fly   268 FFEVDIYGNC---GTLSCTRGDPHCAEMLDTD--------YFFYLAFENSLCDDYVTEKLFDALE 321
            :.|||.||.|   ..|.....:|   ..:|.|        |.|.|||||::||||:|||.:..|:
Mouse   237 YIEVDSYGECLQNRDLPQQLKNP---ASMDADAFYRVIAQYKFILAFENAVCDDYITEKFWRPLK 298

  Fly   322 RTVIPVVFGGADYSRILPPH-SYVDANRFMSVEGLAQYMKLVVADPDLYVSYFWWR-----SHYR 380
            ..|:||.:|....:..||.: |.:..:.|.....||.:::.:..|..||.:|..|:     |:.|
Mouse   299 LGVVPVYYGSPTIADWLPSNRSAILVSEFSHPRELASFIRRLDYDDGLYETYVEWKLKGKISNQR 363

  Fly   381 L-----------------TYSSPF-CDLCARLHDPSFGHKTQFYHDIQSWWFNSCRLQSR 422
            |                 .|...| |.:|.|:                  |.|| |||.:
Mouse   364 LLTALNEREWGVQDINQDNYIDSFECMVCRRV------------------WANS-RLQEQ 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FucTC	NP_001036320.3	Glyco_tran_10_N	82..203	CDD:465336	27/141 (19%)
		Glyco_transf_10	238..412	CDD:459962	54/208 (26%)
Pofut3	NP_001012535.1	Glyco_tran_10_N	82..177	CDD:465336	24/122 (20%)
		Glyco_transf_10	219..>354	CDD:459962	44/137 (32%)