Protein Alignment FucTC and FUT9

DIOPT Version :10

• Sequence 1: NP_001036320.3
• Gene: FucTC / 3355171
• FlyBaseID: FBgn0044872
• Length: 425
• Species: Drosophila melanogaster
• Sequence 2: NP_006572.2
• Gene: FUT9 / 10690
• HGNCID: 4020
• Length: 359
• Species: Homo sapiens
• Alignment Length: 416
• Identity: 106/416 - (25%)
• Similarity: 176/416 - (42%)
• Gaps: 99/416 - (23%)

  Fly    37 RGAL--LLLLLVLLG----VLVVLHKVTQ----SPLLNQNKILQ-DHLRGQHERYIQSTRTILLW 90
            :|.|  .|::.::||    .|::..|.|.    ||:.:.:.:|: .:.......|...| |||:|
Human     6 KGILRPFLIVCIILGCFMACLLIYIKPTNSWIFSPMESASSVLKMKNFFSTKTDYFNET-TILVW 69

  Fly    91 TEFFGDSRWKLSWDTLGPQELRDELHCPVYQCEISNQNAFLPAVELYD---AIVFHAAEMFPLLR 152
            ...||.     ::|....|.:.:     :..|.::...:      ||:   |::.|..::...|.
Human    70 VWPFGQ-----TFDLTSCQAMFN-----IQGCHLTTDRS------LYNKSHAVLIHHRDISWDLT 118

  Fly   153 PVPSQ-RSPHQVYVFALMEPPGETKHRLDDEQGFYNLTMTYRIDSDVFWPYGQLLDITADAVV-- 214
            .:|.| |.|.|.:::..:|.|..|..:...|. .:|||:|||.|||:..||| .|.::.:..|
Human   119 NLPQQARPPFQKWIWMNLESPTHTPQKSGIEH-LFNLTLTYRRDSDIQVPYG-FLTVSTNPFVFE 181

  Fly   215 APSVKPPWRKPPVAFNDSLVWDLWSGKTKTAAWFVSHCETLSKREVLANRLQEFFEVDIYGNC-- 277
            .||                       |.|...|.||:......|....|.|.:..|:..||..
Human   182 VPS-----------------------KEKLVCWVVSNWNPEHARVKYYNELSKSIEIHTYGQAFG 223

  Fly   278 ---------GTLSCTRGDPHCAEMLDTDYFFYLAFENSLCDDYVTEKLFDALERTVIPVVFGGA- 332
                     .|:|..:              |||:||||:..||:||||::|.....:|||.|.:
Human   224 EYVNDKNLIPTISTCK--------------FYLSFENSIHKDYITEKLYNAFLAGSVPVVLGPSR 274

  Fly   333 -DYSRILPPHSYVDANRFMSVEGLAQYMKLVVADPDLYVSYFWWRSHYRLT----YSSPFCDLCA 392
             :|...:|..|::....:.|...||:|:|.|..:..||:|||.||..:.:.    :.|..|..|.
Human   275 ENYENYIPADSFIHVEDYNSPSELAKYLKEVDKNNKLYLSYFNWRKDFTVNLPRFWESHACLACD 339

  Fly   393 RLHDPSFGHKTQFYH---DIQSWWFN 415
            .:      .:.|.|.   :::.|::|
Human   340 HV------KRHQEYKSVGNLEKWFWN 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FucTC	NP_001036320.3	Glyco_tran_10_N	82..203	CDD:465336	34/124 (27%)
		Glyco_transf_10	238..412	CDD:459962	52/193 (27%)
FUT9	NP_006572.2	Glyco_tran_10_N	62..169	CDD:465336	34/124 (27%)
		Acceptor-binding. /evidence=ECO:0000269|PubMed:37202521	63..168		33/122 (27%)
		Donor-binding. /evidence=ECO:0000269|PubMed:37202521	169..326		52/194 (27%)
		Glyco_transf_10	182..356	CDD:459962	54/216 (25%)
		Acceptor-binding. /evidence=ECO:0000269|PubMed:37202521	327..359		6/37 (16%)