Protein Alignment CG40485 and ORA1

DIOPT Version :10

• Sequence 1: NP_001036313.1
• Gene: CG40485 / 3355165
• FlyBaseID: FBgn0069973
• Length: 247
• Species: Drosophila melanogaster
• Sequence 2: NP_013953.1
• Gene: ORA1 / 855266
• SGDID: S000004839
• Length: 267
• Species: Saccharomyces cerevisiae
• Alignment Length: 263
• Identity: 77/263 - (29%)
• Similarity: 137/263 - (52%)
• Gaps: 32/263 - (12%)

  Fly     2 ERWHNCVAVVTGASSGIGAAITRKLISAG---VMVVALARRMDRLEQLREELPQD-RRSRLRIMQ 62
            ||......::||||:|||.|...:.:.|.   :.::..|||:::||:|::.:.|: ..:::.:.|
Yeast     9 ERLAKKTVLITGASAGIGKATALEYLEASNGDMKLILAARRLEKLEELKKTIDQEFPNAKVHVAQ 73

  Fly    63 CDVSDVSSVNAVFDAVQGDLGNVDILINNAGKLSG----GQLLTMSVDTVQQMLQTNVMGVVYCT 123
            .|::....:....:.:..:..::|||:|||||..|    ||:.|   :.:|.:..|||..::..|
Yeast    74 LDITQAEKIKPFIENLPQEFKDIDILVNNAGKALGSDRVGQIAT---EDIQDVFDTNVTALINIT 135

  Fly   124 QRAFESMRQRQSKGHVVLINSIVGHYIFNPLPGSQQELNMYPATKHAITALTELFRQEMRDFKTK 188
            | |...:.|.::.|.:|.:.||.|...:.  .||     :|.|:|.|:.|.|:..|:|:  ..||
Yeast   136 Q-AVLPIFQAKNSGDIVNLGSIAGRDAYP--TGS-----IYCASKFAVGAFTDSLRKEL--INTK 190

  Fly   189 VKVTSISPGLVDTELVPLDYKG-----------LPMLQAEDVANAIMYVLSTPPHVQVHELTIKP 242
            ::|..|:||||:||...:.|:|           ...|.|:|||:.|:|..|...:..:.:..|.|
Yeast   191 IRVILIAPGLVETEFSLVRYRGNEEQAKNVYKDTTPLMADDVADLIVYATSRKQNTVIADTLIFP 255

  Fly   243 LGE 245
            ..:
Yeast   256 TNQ 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG40485	NP_001036313.1	Rossmann-fold NAD(P)(+)-binding proteins	1..242	CDD:473865	76/258 (29%)
ORA1	NP_013953.1	SDR_c5	14..266	CDD:187604	75/258 (29%)