Protein Alignment CG40485 and Dhrs1

DIOPT Version :10

• Sequence 1: NP_001036313.1
• Gene: CG40485 / 3355165
• FlyBaseID: FBgn0069973
• Length: 247
• Species: Drosophila melanogaster
• Sequence 2: NP_081095.2
• Gene: Dhrs1 / 52585
• MGIID: 1196314
• Length: 313
• Species: Mus musculus
• Alignment Length: 262
• Identity: 72/262 - (27%)
• Similarity: 108/262 - (41%)
• Gaps: 61/262 - (23%)

  Fly     8 VAVVTGASSGIGAAITRKLISAGVMVVALARRMDRLEQLREELPQDRRSRLRIMQCDVSDVSSVN 72
            |.||||||.|||..|..:|..||..|....|.:|.|....:| .|....|...:.||.|..|.|.
Mouse     9 VCVVTGASRGIGRGIALQLCKAGATVYITGRHLDTLRATAQE-AQSLGGRCVPVVCDSSQESEVK 72

  Fly    73 AVFDAVQGD-LGNVDILINNAGKLSGGQLLTMSVDTVQQMLQTNVMGVVYCTQRAF--------E 128
            ::|:.|..: .|.:|:|:|||  .:|          ||.:|.|        |.::|        :
Mouse    73 SLFEQVDREQKGRLDVLVNNA--YAG----------VQAILNT--------TNKSFWEVPASIWD 117

  Fly   129 SMRQRQSKGHVVLINSIVGHYIFNPL----------PGSQQEL-NM-YPATKHAITALTELFRQE 181
            .:.....:||.:.  |:.|..:..|.          ||..|.: |: |...|.|...|......|
Mouse   118 DINNVGLRGHYLC--SVYGARLMVPAGKGLIVIVSSPGGLQHMFNVPYGVGKAACDRLAADCAHE 180

  Fly   182 MRDFKTKVKVTSISPGLVDTELV------------PLDYKGLP---MLQAEDVANAIMYVLSTPP 231
            :|  :..|...|:.||||.||:|            ||..|..|   ..::.:::...:..|:|.|
Mouse   181 LR--RHGVSYVSLWPGLVQTEMVKEFMAKEDTPEDPLFKKMKPDFSSAESPEMSGKCVVALATDP 243

  Fly   232 HV 233
            ::
Mouse   244 NI 245

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG40485	NP_001036313.1	Rossmann-fold NAD(P)(+)-binding proteins	1..242	CDD:473865	72/262 (27%)
Dhrs1	NP_081095.2	DHRS1-like_SDR_c	5..271	CDD:187664	72/262 (27%)