Protein Alignment CG40485 and HSD11B1L

DIOPT Version :10

• Sequence 1: NP_001036313.1
• Gene: CG40485 / 3355165
• FlyBaseID: FBgn0069973
• Length: 247
• Species: Drosophila melanogaster
• Sequence 2: NP_001254797.1
• Gene: HSD11B1L / 374875
• HGNCID: 30419
• Length: 333
• Species: Homo sapiens
• Alignment Length: 219
• Identity: 49/219 - (22%)
• Similarity: 92/219 - (42%)
• Gaps: 11/219 - (5%)

  Fly    10 VVTGASSGIGAAITRKLISAGVMVVALARRMDRLEQLREELPQDRRSRLRIMQCDVSDVSSVNAV 74
            ::|||::|:|..:.......|..:|..|.....|:::.....:....::..:..|::...:..:|
Human    80 LLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIAADMASPEAPESV 144

  Fly    75 FDAVQGDLGNVDILI-NNAGKLSGGQLLTMSVDTVQQMLQTNVMGVVYCTQRAFESMRQRQSKGH 138
            .......||.:|.|: |:.|....| ....|....:.::|.|.:..|..|.||..|:  ..|||.
Human   145 VQFALDKLGGLDYLVLNHIGGAPAG-TRARSPQATRWLMQVNFVSYVQLTSRALPSL--TDSKGS 206

  Fly   139 VVLINSIVGHYIFNPLPGSQQELNMYPATKHAITALTELFRQEMRDFKTKVKVTSISPGLVDTEL 203
            :|:::|::|.     :|.|..  ..|.|.|.|:.......|:|:......|.:|....||.|...
Human   207 LVVVSSLLGR-----VPTSFS--TPYSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRAS 264

  Fly   204 VPLDYKGLPMLQAEDVANAIMYVL 227
            .....:|:..::|.....|.:.|:
Human   265 AAEAVRGVTRVKAAPGPKAALAVI 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG40485	NP_001036313.1	Rossmann-fold NAD(P)(+)-binding proteins	1..242	CDD:473865	49/219 (22%)
HSD11B1L	NP_001254797.1	Rossmann-fold NAD(P)(+)-binding proteins	74..302	CDD:473865	49/219 (22%)