DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG40485 and HSD11B1L

DIOPT Version :9

Sequence 1:NP_001036313.1 Gene:CG40485 / 3355165 FlyBaseID:FBgn0069973 Length:247 Species:Drosophila melanogaster
Sequence 2:NP_001254797.1 Gene:HSD11B1L / 374875 HGNCID:30419 Length:333 Species:Homo sapiens


Alignment Length:219 Identity:49/219 - (22%)
Similarity:92/219 - (42%) Gaps:11/219 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 VVTGASSGIGAAITRKLISAGVMVVALARRMDRLEQLREELPQDRRSRLRIMQCDVSDVSSVNAV 74
            ::|||::|:|..:.......|..:|..|.....|:::.....:....::..:..|::...:..:|
Human    80 LLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIAADMASPEAPESV 144

  Fly    75 FDAVQGDLGNVDILI-NNAGKLSGGQLLTMSVDTVQQMLQTNVMGVVYCTQRAFESMRQRQSKGH 138
            .......||.:|.|: |:.|....| ....|....:.::|.|.:..|..|.||..|:  ..|||.
Human   145 VQFALDKLGGLDYLVLNHIGGAPAG-TRARSPQATRWLMQVNFVSYVQLTSRALPSL--TDSKGS 206

  Fly   139 VVLINSIVGHYIFNPLPGSQQELNMYPATKHAITALTELFRQEMRDFKTKVKVTSISPGLVDTEL 203
            :|:::|::|.     :|.|..  ..|.|.|.|:.......|:|:......|.:|....||.|...
Human   207 LVVVSSLLGR-----VPTSFS--TPYSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRAS 264

  Fly   204 VPLDYKGLPMLQAEDVANAIMYVL 227
            .....:|:..::|.....|.:.|:
Human   265 AAEAVRGVTRVKAAPGPKAALAVI 288

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG40485NP_001036313.1 YdfG 1..247 CDD:226674 49/219 (22%)
NADB_Rossmann 1..242 CDD:304358 49/219 (22%)
HSD11B1LNP_001254797.1 GVQW 3..>26 CDD:290611
NADB_Rossmann 74..302 CDD:304358 49/219 (22%)
PRK08251 78..302 CDD:181324 49/219 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1205
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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