Protein Alignment CG40485 and HSD11B1

DIOPT Version :9

• Sequence 1: NP_001036313.1
• Gene: CG40485 / 3355165
• FlyBaseID: FBgn0069973
• Length: 247
• Species: Drosophila melanogaster
• Sequence 2: NP_001193670.1
• Gene: HSD11B1 / 3290
• HGNCID: 5208
• Length: 292
• Species: Homo sapiens
• Alignment Length: 221
• Identity: 53/221 - (23%)
• Similarity: 92/221 - (41%)
• Gaps: 37/221 - (16%)

  Fly    10 VVTGASSGIGAAITRKLISAGVMVVALARRMDRLEQLREELPQDRRSRLRIMQCDVSDVSSVNAV 74
            :|||||.|||..:...|...|..||..||..:.|:::             :..|.....:|.:.:
Human    38 IVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKV-------------VSHCLELGAASAHYI 89

  Fly    75 FDAVQGDLGNVDILINNAGKLSGG--------------QLLTMSVDTVQQMLQTNVMGVVYCTQR 125
            ...:: |:...:..:..||||.||              .|....:..|::.::.|.:..|..|..
Human    90 AGTME-DMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVA 153

  Fly   126 AFESMRQRQSKGHVVLINSIVGHYIFNPLPGSQQELNMYPATKHAITALTELFRQEMRDFKTKVK 190
            |...:  :||.|.:|:::|:.|...: |:..:      |.|:|.|:.......|:|....:..|.
Human   154 ALPML--KQSNGSIVVVSSLAGKVAY-PMVAA------YSASKFALDGFFSSIRKEYSVSRVNVS 209

  Fly   191 VTSISPGLVDTELVPLDYKGLPMLQA 216
            :|....||:|||.......|:..:||
Human   210 ITLCVLGLIDTETAMKAVSGIVHMQA 235

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG40485	NP_001036313.1	YdfG	1..247	CDD:226674	53/221 (24%)
		NADB_Rossmann	1..242	CDD:304358	53/221 (24%)
HSD11B1	NP_001193670.1	11beta-HSD1_like_SDR_c	32..279	CDD:187593	53/221 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1205
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900