DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG40485 and CG9360

DIOPT Version :9

Sequence 1:	NP_001036313.1	Gene:	CG40485 / 3355165	FlyBaseID:	FBgn0069973	Length:	247	Species:	Drosophila melanogaster
Sequence 2:	NP_572746.1	Gene:	CG9360 / 32128	FlyBaseID:	FBgn0030332	Length:	251	Species:	Drosophila melanogaster

Alignment Length:	254	Identity:	124/254 - (48%)
Similarity:	175/254 - (68%)	Gaps:	14/254 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MERWHNCVAVVTGASSGIGAAITRKLISAGVMVVALARRMDRLEQLREELPQDRRSRLRIMQCDV 65
            |:||.|.||||||||||||||..:.|:|.|::||.||||.|||::|:..||.|:.||....:|||
  Fly     1 MDRWLNRVAVVTGASSGIGAACCKDLVSKGLVVVGLARREDRLQELKASLPADQASRFHGRKCDV 65

  Fly    66 SDVSSVNAVFDAVQGDLGNVDILINNAGKLSGGQLLTMSVD--TVQQMLQTNVMGVVYCTQRAFE 128
            |....|...|..:...||..|:|:||||.:..|..:|...:  .::.:|.|||:||.:||:.||:
  Fly    66 SQEQEVIDAFAWIDATLGGADVLVNNAGIVRLGVGITHEGNGADLRAILDTNVLGVSWCTREAFK 130

  Fly   129 SMRQRQ-SKGHVVLINSIVGHYIFNPLPGSQQELNMYPATKHAITALTELFRQEMRDFKTKVKVT 192
            |:::|. :.||::::||:.||.:.|. ||.  .:.||..:|:|:|||||:.|||..:.||:.|:|
  Fly   131 SLKRRNVNDGHILIVNSVAGHRVINN-PGI--TMGMYSPSKYAVTALTEVLRQEFHNNKTQTKIT 192

  Fly   193 SISPGLVDTELVPLDYKGL------PMLQAEDVANAIMYVLSTPPHVQVHELTIKPLGE 245
            |||||.||||::  |.:.|      |||::||||:||.|.:.|||:||:|||||||:||
  Fly   193 SISPGAVDTEII--DKEALVGIPDFPMLRSEDVADAISYCIQTPPNVQIHELTIKPVGE 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG40485	NP_001036313.1	YdfG	1..247	CDD:226674	124/254 (49%)
CG40485	NP_001036313.1	NADB_Rossmann	1..242	CDD:304358	120/249 (48%)
CG9360	NP_572746.1	YdfG	1..250	CDD:226674	124/254 (49%)
CG9360	NP_572746.1	NADB_Rossmann	1..246	CDD:304358	120/249 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442641
Domainoid	1	1.000	86	1.000	Domainoid score	I2775
eggNOG	1	0.900	-	-		E2759_KOG1205
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	87	1.000	Inparanoid score	I2312
Isobase	1	0.950	-	0	Normalized mean entropy	S2090
OMA	1	1.010	-	-		QHG45743
OrthoDB	1	1.010	-	-		D101130at6960
OrthoFinder	1	1.000	-	-		FOG0000588
OrthoInspector	1	1.000	-	-		mtm6354
orthoMCL	1	0.900	-	-		OOG6_100320
Panther	1	1.100	-	-	P	PTHR43115
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1880
SonicParanoid	1	1.000	-	-		X367
	13	12.880