DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG40485 and CG10962

DIOPT Version :9

Sequence 1:	NP_001036313.1	Gene:	CG40485 / 3355165	FlyBaseID:	FBgn0069973	Length:	247	Species:	Drosophila melanogaster
Sequence 2:	NP_788887.1	Gene:	CG10962 / 31824	FlyBaseID:	FBgn0030073	Length:	249	Species:	Drosophila melanogaster

Alignment Length:	250	Identity:	124/250 - (49%)
Similarity:	175/250 - (70%)	Gaps:	4/250 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MERWHNCVAVVTGASSGIGAAITRKLISAGVMVVALARRMDRLEQLREELPQDRRSRLRIMQCDV 65
            |:||.|.|||::|||||||||..|.|::||:.||.||||.|||||||:.||.::|.|....:|||
  Fly     1 MDRWQNRVAVISGASSGIGAACARLLVAAGLQVVGLARRTDRLEQLRQSLPAEQRMRFHQHKCDV 65

  Fly    66 SDVSSVNAVFDAVQGDLGNVDILINNAGKLSGGQLLTMSVDTVQQMLQTNVMGVVYCTQRAFESM 130
            |....|:..|:.::.:||.:|:||||||.:.||||:.|....:..:||||:||.:|||:.|..||
  Fly    66 SQELQVDTAFEWIEKELGGIDVLINNAGIVLGGQLIDMPTKDINNILQTNLMGSIYCTKLAASSM 130

  Fly   131 RQRQSKGHVVLINSIVGHYIFNPLPGSQQELNMYPATKHAITALTELFRQEMRDFKTKVKVTSIS 195
            |:||..||::.:||..|...:.|.| :.:.||.|..:|.|:||:.|:.|||:.:..:|:|.|||:
  Fly   131 RRRQVAGHLIFVNSTAGVAGYKPDP-ADESLNAYTPSKFALTAVQEICRQELINQGSKIKTTSIN 194

  Fly   196 PGLVDTELVPLDYK---GLPMLQAEDVANAIMYVLSTPPHVQVHELTIKPLGEPF 247
            ||.|.||:||.:.|   |..:|||:|||.|::|.||||||.||.::|::.:||.|
  Fly   195 PGWVATEIVPDETKAKLGEVILQADDVAQAVLYALSTPPHTQVEQITLRAVGEYF 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG40485	NP_001036313.1	YdfG	1..247	CDD:226674	123/248 (50%)
CG40485	NP_001036313.1	NADB_Rossmann	1..242	CDD:304358	121/243 (50%)
CG10962	NP_788887.1	YdfG	1..249	CDD:226674	123/248 (50%)
CG10962	NP_788887.1	NADB_Rossmann	1..243	CDD:304358	121/242 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442628
Domainoid	1	1.000	86	1.000	Domainoid score	I2775
eggNOG	1	0.900	-	-		E2759_KOG1205
Homologene	1	1.000	-	-		H41560
Inparanoid	1	1.050	87	1.000	Inparanoid score	I2312
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45743
OrthoDB	1	1.010	-	-		D101130at6960
OrthoFinder	1	1.000	-	-		FOG0000588
OrthoInspector	1	1.000	-	-		mtm6354
orthoMCL	1	0.900	-	-		OOG6_100320
Panther	1	1.100	-	-	P	PTHR43115
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X367
	12	11.900