Protein Alignment CG40485 and Dhrs7b

DIOPT Version :10

• Sequence 1: NP_001036313.1
• Gene: CG40485 / 3355165
• FlyBaseID: FBgn0069973
• Length: 247
• Species: Drosophila melanogaster
• Sequence 2: NP_663403.1
• Gene: Dhrs7b / 216820
• MGIID: 2384931
• Length: 323
• Species: Mus musculus
• Alignment Length: 262
• Identity: 83/262 - (31%)
• Similarity: 124/262 - (47%)
• Gaps: 35/262 - (13%)

  Fly     6 NCVAVVTGASSGIGAAITRKLISAGVMVVALARRMDRLEQLREEL---PQDRRSRLRIMQCDVSD 67
            |.|.|||||:||:|....:...:||..:|...|.:..||:|..||   .|.:..:..::..|::|
Mouse    52 NAVVVVTGATSGLGRECAKVFHAAGAKLVLCGRNVKALEELSRELAGSSQGQTHQPFVVTFDLAD 116

  Fly    68 VSSVNAVFDAVQGDLGNVDILINNAGKLSGGQLLTMSVDTVQQMLQTNVMGVVYCTQRAFESMRQ 132
            ..::.|....:....|.||:||||||....|.:....||..:::::.|..|.|..|:....||.:
Mouse   117 PGTIAAAAAEILQCFGYVDVLINNAGISYRGTISDTIVDVDRKVMEINYFGPVALTKALLPSMVE 181

  Fly   133 RQSKGHVVLINSIVGHYIFNPLPGSQQELNMYPATKHAITALTELFRQEMRDFKTKVKVTSISPG 197
            |: :||:|.|:||.|. |..|...:      |.|:|||..|..:..|.||.:  ..:|||.||||
Mouse   182 RK-QGHIVAISSIQGK-ISIPFRSA------YSASKHATQAFFDCLRAEMEE--ANIKVTVISPG 236

  Fly   198 LVDTEL----VPLDYKGLPMLQ------------AEDVANAI----MYVLSTP--PHVQVHELTI 240
            .:.|.|    |..|......|.            |:||.:|:    ..||.|.  |.:.|:..|:
Mouse   237 YIHTNLSVNAVTADGSRYGALDKNTAQGRSAAEVAQDVFDAVGKKKKDVLLTDFVPSMAVYIRTL 301

  Fly   241 KP 242
            .|
Mouse   302 AP 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG40485	NP_001036313.1	Rossmann-fold NAD(P)(+)-binding proteins	1..242	CDD:473865	82/260 (32%)
Dhrs7b	NP_663403.1	11beta-HSD1_like_SDR_c	50..309	CDD:187593	83/262 (32%)