Protein Alignment CG40485 and DHRS7C

DIOPT Version :10

• Sequence 1: NP_001036313.1
• Gene: CG40485 / 3355165
• FlyBaseID: FBgn0069973
• Length: 247
• Species: Drosophila melanogaster
• Sequence 2: NP_001207422.1
• Gene: DHRS7C / 201140
• HGNCID: 32423
• Length: 312
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 68/265 - (25%)
• Similarity: 117/265 - (44%)
• Gaps: 38/265 - (14%)

  Fly     6 NCVAVVTGASSGIGAAITRKLISAGVMVVALARRMDRLEQLREEL-----PQDRRSRLRIMQCDV 65
            |.|.|:|.|.||:|....|...:.|..:|...:..:|||.|.:.|     |..:....:::..|:
Human    37 NKVVVITDAISGLGKECARVFHTGGARLVLCGKNWERLENLYDALISVADPSKQTFTPKLVLLDL 101

  Fly    66 SDVSSVNAVFDAVQGDLGNVDILINNAGKLSGGQLLTMSVDTVQQMLQTNVMGVVYCTQRAFESM 130
            ||:|.|..|...|....|.||||||||.....|....:|::..::::..|..|.:..|:....:|
Human   102 SDISCVPDVAKEVLDCYGCVDILINNASVKVKGPAHKISLELDKKIMDANYFGPITLTKALLPNM 166

  Fly   131 RQRQSKGHVVLINSIVGHYIFNPLPGSQQELNMYPATKHAITALTELFRQEMRDFKTKVKVTSIS 195
            ..|:: |.:||:|:|.|.:   .:|..    ..|.|:|||.....:..|.|:.::  .|.::::|
Human   167 ISRRT-GQIVLVNNIQGKF---GIPFR----TTYAASKHAALGFFDCLRAEVEEY--DVVISTVS 221

  Fly   196 PGLVDTELV-----------------PLDYKGLPMLQAEDVANAI------MYVLSTPPHVQVHE 237
            |..:.:..|                 .|.|...|:..||:|...:      :::.:..|...|:.
Human   222 PTFIRSYHVYPEQGNWEASIWKFFFRKLTYGVHPVEVAEEVMRTVRRKKQEVFMANPIPKAAVYV 286

  Fly   238 LTIKP 242
            .|..|
Human   287 RTFFP 291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG40485	NP_001036313.1	Rossmann-fold NAD(P)(+)-binding proteins	1..242	CDD:473865	67/263 (25%)
DHRS7C	NP_001207422.1	11beta-HSD1_like_SDR_c	35..297	CDD:187593	68/265 (26%)