DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG40485 and Rdh1

DIOPT Version :9

Sequence 1:	NP_001036313.1	Gene:	CG40485 / 3355165	FlyBaseID:	FBgn0069973	Length:	247	Species:	Drosophila melanogaster
Sequence 2:	NP_536684.2	Gene:	Rdh1 / 107605	MGIID:	1195275	Length:	317	Species:	Mus musculus

Alignment Length:	190	Identity:	54/190 - (28%)
Similarity:	88/190 - (46%)	Gaps:	19/190 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 VTGASSGIGAAITRKLISAGVMVVALARRMDRLEQLREELPQDRRSRLRIMQCDVSDVSSVNAVF 75
            :||..||.|..:.|:|...|:.|:|..    ..|:..|||......||..:..||:...|:.|..
Mouse    34 ITGCDSGFGNLLARQLDRRGMRVLAAC----LTEKGAEELRNKTSDRLETVILDVTKTESIVAAT 94

  Fly    76 DAVQGDLGNVDI--LINNAG-KLSGGQLLTMSVDTVQQMLQTNVMGVVYCTQRAFESMRQRQSKG 137
            ..|:..:||..:  |:|||| ....|....|......::|..|::|::..|......:  |:::|
Mouse    95 QWVKERVGNRGLWGLVNNAGISTPSGPNEWMKKQDFARVLDVNLLGMIEVTLSMLPLV--RKARG 157

  Fly   138 HVVLINSIVGHYIFNPLPGSQQELNMYPATKHAITALTELFRQEMRDFKTKVKVTSISPG 197
            .||.::|::|...|  ..|.      |..:|:.:.|.::..|:|:..|  .|||..|.||
Mouse   158 RVVNVSSVMGRMSF--FGGG------YCISKYGVEAFSDSLRRELSYF--GVKVAIIEPG 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG40485	NP_001036313.1	YdfG	1..247	CDD:226674	54/190 (28%)
CG40485	NP_001036313.1	NADB_Rossmann	1..242	CDD:304358	54/190 (28%)
Rdh1	NP_536684.2	type2_17beta_HSD-like_SDR_c	30..306	CDD:187665	54/190 (28%)
Rdh1	NP_536684.2	adh_short	30..211	CDD:278532	54/190 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1880
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030