Protein Alignment Rab21 and RAB2B

DIOPT Version :10

• Sequence 1: NP_001036321.2
• Gene: Rab21 / 3355163
• FlyBaseID: FBgn0039966
• Length: 222
• Species: Drosophila melanogaster
• Sequence 2: NP_116235.2
• Gene: RAB2B / 84932
• HGNCID: 20246
• Length: 216
• Species: Homo sapiens
• Alignment Length: 214
• Identity: 74/214 - (34%)
• Similarity: 125/214 - (58%)
• Gaps: 11/214 - (5%)

  Fly    14 FKAVLLGEGCVGKTSLVLRYMEDRFNAQHLSTLQASFVSRKMSLEDGRRAQLNIWDTAGQERFHA 78
            ||.:::|:..|||:.|:|::.:.||...|..|:...|.:|.::: ||::.:|.||||||||.|.:
Human     7 FKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNI-DGKQIKLQIWDTAGQESFRS 70

  Fly    79 LGPIYYRGSDGALLVYDITDRDSFQKVKSWVRELRQMRGTEIALIIVGNKTDLEEQRAVTHDEAL 143
            :...||||:.|||||||||.|::|..:.||:.:.||...:.:.::::|||:|||.:|.|..:|..
Human    71 ITRSYYRGAAGALLVYDITRRETFNHLTSWLEDARQHSSSNMVIMLIGNKSDLESRRDVKREEGE 135

  Fly   144 QYARTVGAQYVETSAKENEGVAELFELLTQLMLEQLSQR----QPDASPLRL---QNPDTDNLNN 201
            .:||..|..::|||||....|.|.|....:.:..::.|.    ..:|:.:::   |:..|....:
Human   136 AFAREHGLIFMETSAKTACNVEEAFINTAKEIYRKIQQGLFDVHNEANGIKIGPQQSISTSVGPS 200

  Fly   202 SDDSEAPDPGDPAGQRSCC 220
            :....:.|.|..:|   ||
Human   201 ASQRNSRDIGSNSG---CC 216

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab21	NP_001036321.2	Rab21	14..176	CDD:133323	65/161 (40%)
RAB2B	NP_116235.2	PLN03108	1..216	CDD:178655	72/212 (34%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P61106	37..42		1/4 (25%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P61106	63..72		5/8 (63%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	189..216		5/29 (17%)