DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab21 and rab21

DIOPT Version :9

Sequence 1:	NP_001036321.2	Gene:	Rab21 / 3355163	FlyBaseID:	FBgn0039966	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_001016319.1	Gene:	rab21 / 549073	XenbaseID:	XB-GENE-486436	Length:	221	Species:	Xenopus tropicalis

Alignment Length:	219	Identity:	120/219 - (54%)
Similarity:	153/219 - (69%)	Gaps:	23/219 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 TLNFKAVLLGEGCVGKTSLVLRYMEDRFNAQHLSTLQASFVSRKMSLEDGRRAQLNIWDTAGQER 75
            |.:||.|||||||||||||||||.|::||.:|::||||||:::|::: .|:|..|.|||||||||
Frog    15 TYSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNI-GGKRVNLAIWDTAGQER 78

  Fly    76 FHALGPIYYRGSDGALLVYDITDRDSFQKVKSWVRELRQMRGTEIALIIVGNKTDLEEQRAVTHD 140
            ||||||||||.|:||:|||||||.|||||||:||:|||:|.|.||.|.|||||.|||::|.|:..
Frog    79 FHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKMLGNEICLCIVGNKVDLEKERHVSVQ 143

  Fly   141 EALQYARTVGAQYVETSAKENEGVAELFELLTQLMLE--QLSQR-------QPDASPLRLQNPDT 196
            ||..||.:|||::..||||:|:|:.|||..|.:.|:|  |..:|       |...|...:|..|
Frog   144 EAETYAESVGAKHYHTSAKQNKGIEELFLDLCKRMIETAQTDERAKGNGPSQSGTSRRGVQIVD- 207

  Fly   197 DNLNNSDDSEAPDPGDPAGQRSCC 220
                  |:.:|...|      .||
Frog   208 ------DEPQAQSTG------GCC 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab21	NP_001036321.2	Rab21	14..176	CDD:133323	106/161 (66%)
Rab21	NP_001036321.2	Ras	15..177	CDD:278499	106/161 (66%)
rab21	NP_001016319.1	Rab21	18..179	CDD:133323	106/161 (66%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	215	1.000	Domainoid score	I2673
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H8991
Inparanoid	1	1.050	222	1.000	Inparanoid score	I3447
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1226895at2759
OrthoFinder	1	1.000	-	-		FOG0006095
OrthoInspector	1	1.000	-	-		oto104387
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4390
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.060