Protein Alignment Rab21 and RAB19

DIOPT Version :10

• Sequence 1: NP_001036321.2
• Gene: Rab21 / 3355163
• FlyBaseID: FBgn0039966
• Length: 222
• Species: Drosophila melanogaster
• Sequence 2: NP_001008749.2
• Gene: RAB19 / 401409
• HGNCID: 19982
• Length: 217
• Species: Homo sapiens
• Alignment Length: 193
• Identity: 62/193 - (32%)
• Similarity: 107/193 - (55%)
• Gaps: 13/193 - (6%)

  Fly    14 FKAVLLGEGCVGKTSLVLRYMEDRFNAQHLSTLQASFVSRKMSLEDGRRAQLNIWDTAGQERFHA 78
            ||.:|:|:..||||.:|..:....:.....:|:...|..|.:.: ||::.::.:|||||||||..
Human    18 FKIILIGDSNVGKTCVVQHFKSGVYTETQQNTIGVDFTVRSLDI-DGKKVKMQVWDTAGQERFRT 81

  Fly    79 LGPIYYRGSDGALLVYDITDRDSFQKVKSWVRELRQMRGTEIALIIVGNKTDLEEQRAVTHDEAL 143
            :...|||.:..|::.||:|.|.:|:.:..|:.|:.:.....:.::::|||.||.|:|.|..::|.
Human    82 ITQSYYRSAHAAIIAYDLTRRSTFESIPHWIHEIEKYGAANVVIMLIGNKCDLWEKRHVLFEDAC 146

  Fly   144 QYARTVGAQYV-ETSAKENEGVAELFELLTQLMLEQ----------LSQRQPDASP-LRLQNP 194
            ..|...|...| ||||||::.:.|:|.|:.:.::.:          |:....|:|| |..|.|
Human   147 TLAEKYGLLAVLETSAKESKNIEEVFVLMAKELIARNSLHLYGESALNGLPLDSSPVLMAQGP 209

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab21	NP_001036321.2	Rab21	14..176	CDD:133323	55/162 (34%)
RAB19	NP_001008749.2	Rab19	15..179	CDD:133267	55/161 (34%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:Q9H0U4	39..54		1/14 (7%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:Q9H0U4	74..89		8/14 (57%)