Protein Alignment Rab21 and RAB12

DIOPT Version :10

• Sequence 1: NP_001036321.2
• Gene: Rab21 / 3355163
• FlyBaseID: FBgn0039966
• Length: 222
• Species: Drosophila melanogaster
• Sequence 2: NP_001020471.3
• Gene: RAB12 / 201475
• HGNCID: 31332
• Length: 340
• Species: Homo sapiens
• Alignment Length: 227
• Identity: 75/227 - (33%)
• Similarity: 122/227 - (53%)
• Gaps: 23/227 - (10%)

  Fly     5 RTRNGP--TLNFK--AVLLGEGCVGKTSLVLRYMEDRFNAQHLSTLQASFVSRKMSLEDGRRAQL 65
            |.|..|  ..:||  .:::|...||||||:.|:.:|.|.....||:...|..:.:.|. |::.:|
Human   126 RRRKQPPRPADFKLQVIIIGSRGVGKTSLMERFTDDTFCEACKSTVGVDFKIKTVELR-GKKIRL 189

  Fly    66 NIWDTAGQERFHALGPIYYRGSDGALLVYDITDRDSFQKVKSWVRELRQMRGTEIALIIVGNKTD 130
            .||||||||||:::...|||.:.|.:||||||.:::|..:..|::.:.:....:..|::||||.|
Human   190 QIWDTAGQERFNSITSAYYRSAKGIILVYDITKKETFDDLPKWMKMIDKYASEDAELLLVGNKLD 254

  Fly   131 LEEQRAVTHDEALQYARTV-GAQYVETSAKENEGVAELFELLTQLMLEQLSQRQPDASPLRLQNP 194
            .|..|.:|..:..::|:.: |.::.|.|||:|..|.|:|..|...:|:::        ||.:..
Human   255 CETDREITRQQGEKFAQQITGMRFCEASAKDNFNVDEIFLKLVDDILKKM--------PLDILR- 310

  Fly   195 DTDNLNNSDDSEAPDP------GDPAGQRSCC 220
              :.|:||..|..|:|      ..|.....||
Human   311 --NELSNSILSLQPEPEIPPELPPPRPHVRCC 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab21	NP_001036321.2	Rab21	14..176	CDD:133323	60/164 (37%)
RAB12	NP_001020471.3	Rab12	139..340	CDD:206699	68/212 (32%)