Protein Alignment CG40486 and CBR1

DIOPT Version :10

• Sequence 1: NP_001036311.2
• Gene: CG40486 / 3355162
• FlyBaseID: FBgn0263830
• Length: 247
• Species: Drosophila melanogaster
• Sequence 2: NP_001748.1
• Gene: CBR1 / 873
• HGNCID: 1548
• Length: 277
• Species: Homo sapiens
• Alignment Length: 244
• Identity: 65/244 - (26%)
• Similarity: 106/244 - (43%)
• Gaps: 63/244 - (25%)

  Fly     8 VAVVTGASSGIGAAVARHL--VSAGVIVVGLARRVDRMKAIKEQLPPE-LQGRLHAIHCDVEDLD 69
            ||:|||.:.|||.|:.|.|  :.:|.:|: .||.|.|.:|..:||..| |..|.|.:  |::||.
Human     7 VALVTGGNKGIGLAIVRDLCRLFSGDVVL-TARDVTRGQAAVQQLQAEGLSPRFHQL--DIDDLQ 68

  Fly    70 SVTAAFDWIEEQLGGCDILVNNAGCL------NPGQLLTLELEQLQQVLNVNLMGV-VICTRRAF 127
            |:.|..|::.::.||.|:||||||..      .|..:      |.:..:..|..|. .:||
Human    69 SIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHI------QAEVTMKTNFFGTRDVCT---- 123

  Fly   128 RSMQQREVDGHVILINSLTGRNIINPPGDELQ---------------VLN--------------- 162
            ..:...:..|.|:.::|:.....:.....|||               ::|
Human   124 ELLPLIKPQGRVVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDTKKGVHQKEG 188

  Fly   163 ----MYPLTKHGVTAMLEV----LRQELRGFKTKIKVTSITPGVTDTEI 203
                .|.:||.|||.:..:    |.::.:|  .||.:.:..||...|::
Human   189 WPSSAYGVTKIGVTVLSRIHARKLSEQRKG--DKILLNACCPGWVRTDM 235

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG40486	NP_001036311.2	Rossmann-fold NAD(P)(+)-binding proteins	1..242	CDD:473865	65/244 (27%)
CBR1	NP_001748.1	carb_red_PTCR-like_SDR_c	6..277	CDD:187585	65/244 (27%)