Protein Alignment CG40486 and DHRS11

DIOPT Version :9

• Sequence 1: NP_001036311.2
• Gene: CG40486 / 3355162
• FlyBaseID: FBgn0263830
• Length: 247
• Species: Drosophila melanogaster
• Sequence 2: NP_077284.2
• Gene: DHRS11 / 79154
• HGNCID: 28639
• Length: 260
• Species: Homo sapiens
• Alignment Length: 259
• Identity: 108/259 - (41%)
• Similarity: 154/259 - (59%)
• Gaps: 26/259 - (10%)

  Fly     1 MERWHDRVAVVTGASSGIGAAVARHLVSAGVIVVGLARRVDRMKAIKEQLPPELQ-----GRLHA 60
            ||||.||:|:|||||.||||||||.||..|:.|||.||.|..:    |:|..|.:     |.|..
Human     6 MERWRDRLALVTGASGGIGAAVARALVQQGLKVVGCARTVGNI----EELAAECKSAGYPGTLIP 66

  Fly    61 IHCDVEDLDSVTAAFDWIEEQLGGCDILVNNAGCLNPGQLLTLELEQLQQVLNVNLMGVVICTRR 125
            ..||:.:.:.:.:.|..|..|..|.||.:||||...|..||:......:.:.|||::.:.||||.
Human    67 YRCDLSNEEDILSMFSAIRSQHSGVDICINNAGLARPDTLLSGSTSGWKDMFNVNVLALSICTRE 131

  Fly   126 AFRSMQQREV-DGHVILINSLTGRNIINPPGDELQVLNMYPLTKHGVTAMLEVLRQELRGFKTKI 189
            |::||::|.| |||:|.|||::|..::     .|.|.:.|..||:.|||:.|.||||||..:|.|
Human   132 AYQSMKERNVDDGHIININSMSGHRVL-----PLSVTHFYSATKYAVTALTEGLRQELREAQTHI 191

  Fly   190 KVTSITPGVTDT-----------EILPSGYGILPMLKPDDIAAGIMYVLGTPAHVQVHELTIKP 242
            :.|.|:|||.:|           |...:.|..:..|||:|:|..::|||.||||:|:.::.::|
Human   192 RATCISPGVVETQFAFKLHDKDPEKAAATYEQMKCLKPEDVAEAVIYVLSTPAHIQIGDIQMRP 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG40486	NP_001036311.2	YdfG	1..247	CDD:226674	108/259 (42%)
		NADB_Rossmann	1..242	CDD:304358	107/257 (42%)
DHRS11	NP_077284.2	Mgc4172-like_SDR_c	6..256	CDD:187601	108/259 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143376
Domainoid	1	1.000	154	1.000	Domainoid score	I4257
eggNOG	1	0.900	-	-		E2759_KOG1205
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41560
Inparanoid	1	1.050	188	1.000	Inparanoid score	I3916
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45743
OrthoDB	1	1.010	-	-		D1190834at2759
OrthoFinder	1	1.000	-	-		FOG0000588
OrthoInspector	1	1.000	-	-		otm40752
orthoMCL	1	0.900	-	-		OOG6_100320
Panther	1	1.100	-	-	O	PTHR43115
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X367
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	14	13.810