Protein Alignment CG40486 and Dhrs7

DIOPT Version :10

• Sequence 1: NP_001036311.2
• Gene: CG40486 / 3355162
• FlyBaseID: FBgn0263830
• Length: 247
• Species: Drosophila melanogaster
• Sequence 2: NP_079798.2
• Gene: Dhrs7 / 66375
• MGIID: 1913625
• Length: 338
• Species: Mus musculus
• Alignment Length: 212
• Identity: 60/212 - (28%)
• Similarity: 99/212 - (46%)
• Gaps: 18/212 - (8%)

  Fly     4 WH--DRVAVVTGASSGIGAAVARHLVSAGVIVVGLARRVDRMKAIKEQLPPELQGRLH-----AI 61
            |.  |.|..|||||||||..:|..|...||.:|..|||...::.:|.:...  .|.|.     .:
Mouse    46 WELTDMVVWVTGASSGIGEELAFQLSKLGVSLVLSARRAQELERVKRRCLE--NGNLKEKDILVL 108

  Fly    62 HCDVEDLDSVTAAFDWIEEQLGGCDILVNNAGCLNPGQLLTLELEQLQQVLNVNLMGVVICTRRA 126
            ..|:.|..|..||...:.::.|..||||||.|......:|...|:..::::|:|.:|.|..|:..
Mouse   109 PLDLTDTSSHEAATKAVLQEFGKIDILVNNGGRSQRSLVLETNLDVFKELINLNYIGTVSLTKCV 173

  Fly   127 FRSMQQREVDGHVILINSLTGRNIINPPGDELQVLNMYPLTKHGVTAMLEVLRQELRGFKTKIKV 191
            ...|.:|: .|.::.:||:.|...::       :.:.|..:||.:......|..|| |....|..
Mouse   174 LPHMIERK-QGKIVTVNSIAGIASVS-------LSSGYCASKHALRGFFNALHSEL-GQYPGITF 229

  Fly   192 TSITPGVTDTEILPSGY 208
            .::.||...::|:.:.:
Mouse   230 CNVYPGPVQSDIVKNAF 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG40486	NP_001036311.2	Rossmann-fold NAD(P)(+)-binding proteins	1..242	CDD:473865	60/212 (28%)
Dhrs7	NP_079798.2	11beta-HSD1_like_SDR_c	48..308	CDD:187593	59/210 (28%)