Protein Alignment CG40486 and Dhrs1

DIOPT Version :10

• Sequence 1: NP_001036311.2
• Gene: CG40486 / 3355162
• FlyBaseID: FBgn0263830
• Length: 247
• Species: Drosophila melanogaster
• Sequence 2: NP_081095.2
• Gene: Dhrs1 / 52585
• MGIID: 1196314
• Length: 313
• Species: Mus musculus
• Alignment Length: 235
• Identity: 63/235 - (26%)
• Similarity: 97/235 - (41%)
• Gaps: 44/235 - (18%)

  Fly     7 RVAVVTGASSGIGAAVARHLVSAGVIVVGLARRVDRMKAIKEQLPPELQGRLHAIHCDVEDLDSV 71
            :|.||||||.|||..:|..|..||..|....|.:|.::|..:: ...|.||...:.||......|
Mouse     8 QVCVVTGASRGIGRGIALQLCKAGATVYITGRHLDTLRATAQE-AQSLGGRCVPVVCDSSQESEV 71

  Fly    72 TAAFDWIE-EQLGGCDILVNNA-----GCLNPGQLLTLELEQ--LQQVLNVNLMGVVICTRRAFR 128
            .:.|:.:: ||.|..|:|||||     ..||.......|:..  ...:.||.|.|..:|:....|
Mouse    72 KSLFEQVDREQKGRLDVLVNNAYAGVQAILNTTNKSFWEVPASIWDDINNVGLRGHYLCSVYGAR 136

  Fly   129 SMQQREVDGHVILINSLTG-RNIINPP-------GDELQVLNMYPLTKHGVTAMLEVLRQELRGF 185
            .|.... .|.:::::|..| :::.|.|       .|.|.....:.|.:|||:
Mouse   137 LMVPAG-KGLIVIVSSPGGLQHMFNVPYGVGKAACDRLAADCAHELRRHGVS------------- 187

  Fly   186 KTKIKVTSITPGVTDTEILPSGYG--------ILPMLKPD 217
                 ..|:.||:..||::.....        :...:|||
Mouse   188 -----YVSLWPGLVQTEMVKEFMAKEDTPEDPLFKKMKPD 222

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG40486	NP_001036311.2	Rossmann-fold NAD(P)(+)-binding proteins	1..242	CDD:473865	63/235 (27%)
Dhrs1	NP_081095.2	DHRS1-like_SDR_c	5..271	CDD:187664	63/235 (27%)